iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106740

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01197652

Gene Name

TRIM24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000005348.1	ENSSHAT00000006200.1	ENSSHAP00000006146.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.70e-09	37.2	725	769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C+vC++gge    l++CekC ++fH +C+ ++   ++p+ e wiC+ Cr
   Q: 725  DWCAVCQNGGE----LLCCEKCPKVFHLTCHVPT-LMNFPSGE-WICTFCR 769
           79*********....*******************.*******8.******8 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MTVRSAPVST NSFNVGVIRC PVCSQECAER HIIDNFFVKD TTEVPSSTVE KSNQVCTSCE 60
DNAEANGFCV ECVEWLCKTC IRAHQRVKFT KDHTVRQKEE VSPEAVGVTS QRPVFCPYHK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCAAATCG ATCCTCCTAT GCCAGACATA TGGGTGTCCT GTCGGAATCT TTGGCCAATG 60
ACTGCGCCAG TTGGCAGCTC TAATGACCGT ACGATCTGCA CCCGTGTCTA CCAACTCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR019786--Zinc_finger_PHD-type_CS
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box

PRINTS

PR00503--BROMODOMAIN

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005719--C:nuclear euchromatin
GO:0005654--C:nucleoplasm
GO:0005726--C:perichromatin fibrils
GO:0003682--F:chromatin binding
GO:0034056--F:estrogen response element binding
GO:0004672--F:protein kinase activity
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0055074--P:calcium ion homeostasis
GO:0071391--P:cellular response to estrogen stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0046777--P:protein autophosphorylation
GO:0030163--P:protein catabolic process
GO:0042981--P:regulation of apoptotic process
GO:0031647--P:regulation of protein stability
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0070562--P:regulation of vitamin D receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001838	Ailuropoda melanoleuca	86.51	0.00e+00	1417.00
IUUC-Apl-003697	Anas platyrhynchos	78.66	0.00e+00	1274.00
IUUC-Ath-006656	Arabidopsis thaliana	48.15	5.00e-12	67.00
IUUC-Bta-013282	Bos taurus	86.31	0.00e+00	1417.00
IUUC-Cja-018920	Callithrix jacchus	85.67	0.00e+00	1423.00
IUUC-Cfa-020984	Canis familiaris	86.74	0.00e+00	1425.00
IUUC-Cpo-022035	Cavia porcellus	85.45	0.00e+00	1457.00
IUUC-Csa-024208	Chlorocebus sabaeus	86.42	0.00e+00	1431.00
IUUC-Dno-029145	Dasypus novemcinctus	86.46	0.00e+00	1474.00
IUUC-Dor-030396	Dipodomys ordii	82.55	0.00e+00	1097.00
IUUC-Ete-032414	Echinops telfairi	79.09	0.00e+00	811.00
IUUC-Eca-033489	Equus caballus	86.63	0.00e+00	1423.00
IUUC-Eeu-034654	Erinaceus europaeus	82.68	0.00e+00	628.00
IUUC-Fca-035844	Felis catus	83.58	0.00e+00	1312.00
IUUC-Fal-036735	Ficedula albicollis	77.78	0.00e+00	1290.00
IUUC-Gga-041124	Gallus gallus	76.84	0.00e+00	1248.00
IUUC-Ggo-044542	Gorilla gorilla	86.52	0.00e+00	1431.00
IUUC-Hsa-046785	Homo sapiens	86.52	0.00e+00	1430.00
IUUC-Itr-048262	Ictidomys tridecemlineatus	86.63	0.00e+00	1429.00
IUUC-Laf-054279	Loxodonta africana	85.04	0.00e+00	1424.00
IUUC-Mcc-055668	Macaca mulatta	86.52	0.00e+00	1432.00
IUUC-Meu-056195	Macropus eugenii	80.77	0.00e+00	853.00
IUUC-Mga-059272	Meleagris gallopavo	77.48	0.00e+00	1258.00
IUUC-Mmr-060936	Microcebus murinus	86.20	0.00e+00	1423.00
IUUC-Mdo-062848	Monodelphis domestica	91.17	0.00e+00	1533.00
IUUC-Mmu-063598	Mus musculus	85.58	0.00e+00	1394.00
IUUC-Mpu-066272	Mustela putorius furo	86.52	0.00e+00	1417.00
IUUC-Mlu-067958	Myotis lucifugus	84.31	0.00e+00	1414.00
IUUC-Nle-069375	Nomascus leucogenys	86.52	0.00e+00	1432.00
IUUC-Opr-070836	Ochotona princeps	73.09	8.00e-158	551.00
IUUC-Oan-073393	Ornithorhynchus anatinus	80.08	0.00e+00	983.00
IUUC-Ocu-074873	Oryctolagus cuniculus	85.32	0.00e+00	1428.00
IUUC-Oga-088692	Otolemur garnettii	85.45	0.00e+00	1387.00
IUUC-Oar-090160	Ovis aries	86.23	0.00e+00	1418.00
IUUC-Ptr-090756	Pan troglodytes	86.52	0.00e+00	1430.00
IUUC-Pan-091719	Papio anubis	86.42	0.00e+00	1430.00
IUUC-Psi-093433	Pelodiscus sinensis	79.16	0.00e+00	1332.00
IUUC-Pab-098599	Pongo abelii	85.03	0.00e+00	1402.00
IUUC-Pca-100540	Procavia capensis	79.59	0.00e+00	862.00
IUUC-Pva-102478	Pteropus vampyrus	79.47	0.00e+00	1261.00
IUUC-Sar-113615	Sorex araneus	84.73	0.00e+00	1236.00
IUUC-Tgu-117368	Taeniopygia guttata	77.46	0.00e+00	1288.00
IUUC-Tsy-118904	Tarsius syrichta	86.30	0.00e+00	1430.00
IUUC-Tbe-127354	Tupaia belangeri	82.01	3.00e-157	549.00
IUUC-Ttr-128983	Tursiops truncatus	83.61	0.00e+00	1043.00
IUUC-Vpa-130420	Vicugna pacos	84.48	0.00e+00	1384.00
IUUC-Vvi-131561	Vitis vinifera	47.17	4.00e-12	66.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence