iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090732

UUCD1 version

UUC-PaT-00467

Ensembl Protein ID

ENSPTRP00000040554.4

UniProt Accession

H2R0D4; H2R0D4_PANTR

Genbank Protein ID

JAA05314.1; JAA16916.1; JAA22597.1; JAA35196.1

Protein Name

Myosin regulatory light chain interacting protein

Genbank Nucleotide ID

AACZ03046916; GABF01005229; GABD01010503; GABE01009543

Gene Name

MYLIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000023743.4	ENSPTRT00000043466.4	ENSPTRP00000040554.4

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.78	0.00e+00	867.00	IUUC-Hsa-046869

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MLCYVTRPDA VLMEVEVEAK ANGEDCLNQV CRRLGIIEVD YFGLQFTGSK GESLWLNLRN 60
RISQQMDGLA PYRLKLRVKF FVEPHLILQE QTRHIFFLHI KEALLAGHLL CSPEQAVELS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTGGGCTG CTGGAGTGCG GCGCCACCGC GGAGGACAGG GGGAGCTGGC GGGCAGCGGG 60
TGAGGGGGTG GCGGGGACGC GAGTGGCGGC CGCGGGGCTC CGGACAAGGG TCCGCAGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR019749--Band_41_domain
IPR001370--BIR_rpt
IPR000798--Ez/rad/moesin-like
IPR014352--FERM/acyl-CoA-bd_prot_3-hlx
IPR019748--FERM_central
IPR000299--FERM_domain
IPR018979--FERM_N
IPR018980--FERM_PH-like_C
IPR011993--PH_dom-like
IPR029071--Ubiquitin-rel_dom
IPR001841--Znf_RING

PROSITE

PS50057--FERM_3
PS50089--ZF_RING_2

Pfam

PF09380--FERM_C
PF00373--FERM_M
PF09379--FERM_N

PRINTS

PR00935--BAND41
PR00661--ERMFAMILY

SMART

SM00295--B41
SM01196--FERM_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019898--C:extrinsic component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042632--P:cholesterol homeostasis
GO:0010989--P:negative regulation of low-density lipoprotein particle clearance
GO:0007399--P:nervous system development
GO:0045732--P:positive regulation of protein catabolic process
GO:0031648--P:protein destabilization
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0032803--P:regulation of low-density lipoprotein particle receptor catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001425	Ailuropoda melanoleuca	95.91	0.00e+00	811.00
IUUC-Apl-003704	Anas platyrhynchos	91.17	0.00e+00	774.00
IUUC-Aca-004645	Anolis carolinensis	89.89	0.00e+00	779.00
IUUC-Ame-011401	Astyanax mexicanus	75.00	0.00e+00	655.00
IUUC-Bta-012752	Bos taurus	94.74	0.00e+00	712.00
IUUC-Cja-019734	Callithrix jacchus	98.43	0.00e+00	858.00
IUUC-Cfa-020145	Canis familiaris	96.05	0.00e+00	738.00
IUUC-Cpo-021436	Cavia porcellus	96.05	0.00e+00	723.00
IUUC-Csa-024248	Chlorocebus sabaeus	99.33	0.00e+00	862.00
IUUC-Cho-024528	Choloepus hoffmanni	84.49	0.00e+00	684.00
IUUC-Cin-025748	Ciona intestinalis	36.33	4.00e-47	181.00
IUUC-Csv-025837	Ciona savignyi	38.56	4.00e-91	328.00
IUUC-Dre-027847	Danio rerio	75.33	0.00e+00	667.00
IUUC-Dno-029860	Dasypus novemcinctus	95.53	0.00e+00	696.00
IUUC-Dor-030664	Dipodomys ordii	83.60	0.00e+00	711.00
IUUC-Dse-031509	Dothistroma septosporum	45.10	8.00e-10	59.30
IUUC-Dme-031990	Drosophila melanogaster	31.53	1.00e-38	154.00
IUUC-Ete-032496	Echinops telfairi	75.81	3.00e-149	521.00
IUUC-Eca-033674	Equus caballus	96.21	0.00e+00	875.00
IUUC-Eeu-035048	Erinaceus europaeus	88.31	0.00e+00	781.00
IUUC-Fca-036547	Felis catus	95.67	0.00e+00	815.00
IUUC-Fal-037504	Ficedula albicollis	91.61	0.00e+00	762.00
IUUC-Fox-037905	Fusarium oxysporum	27.27	9.00e-03	32.70
IUUC-Gmo-038660	Gadus morhua	74.41	6.00e-153	533.00
IUUC-Gga-040123	Gallus gallus	91.91	0.00e+00	809.00
IUUC-Gac-042073	Gasterosteus aculeatus	72.54	0.00e+00	632.00
IUUC-Ggo-045387	Gorilla gorilla	99.78	0.00e+00	867.00
IUUC-Hsa-046869	Homo sapiens	99.78	0.00e+00	874.00
IUUC-Itr-047917	Ictidomys tridecemlineatus	95.06	0.00e+00	838.00
IUUC-Lch-049990	Latimeria chalumnae	82.70	0.00e+00	777.00
IUUC-Lpe-051271	Leersia perrieri	39.62	2.00e-07	54.30
IUUC-Loc-051908	Lepisosteus oculatus	75.89	0.00e+00	676.00
IUUC-Lma-053223	Leptosphaeria maculans	52.50	2.00e-08	55.80
IUUC-Laf-053915	Loxodonta africana	95.28	0.00e+00	837.00
IUUC-Mcc-054865	Macaca mulatta	99.10	0.00e+00	860.00
IUUC-Meu-056826	Macropus eugenii	86.36	2.00e-74	273.00
IUUC-Mga-059827	Meleagris gallopavo	91.21	0.00e+00	731.00
IUUC-Mmr-060734	Microcebus murinus	97.98	0.00e+00	876.00
IUUC-Mdo-062988	Monodelphis domestica	94.83	0.00e+00	860.00
IUUC-Mmu-064415	Mus musculus	96.40	0.00e+00	810.00
IUUC-Mpu-066118	Mustela putorius furo	96.05	0.00e+00	720.00
IUUC-Mlu-067131	Myotis lucifugus	95.73	0.00e+00	833.00
IUUC-Nle-070112	Nomascus leucogenys	99.55	0.00e+00	862.00
IUUC-Opr-071193	Ochotona princeps	93.39	0.00e+00	796.00
IUUC-Ont-072635	Oreochromis niloticus	74.50	0.00e+00	647.00
IUUC-Oan-073266	Ornithorhynchus anatinus	90.62	0.00e+00	758.00
IUUC-Ocu-074903	Oryctolagus cuniculus	94.38	0.00e+00	840.00
IUUC-Ola-087533	Oryzias latipes	71.82	4.00e-177	613.00
IUUC-Oga-087979	Otolemur garnettii	98.43	0.00e+00	887.00
IUUC-Oar-089747	Ovis aries	94.71	0.00e+00	785.00
IUUC-Pan-092032	Papio anubis	99.33	0.00e+00	862.00
IUUC-Psi-093296	Pelodiscus sinensis	91.17	0.00e+00	784.00
IUUC-Pma-094351	Petromyzon marinus	50.28	2.00e-32	131.00
IUUC-Pfo-097183	Poecilia formosa	73.74	6.00e-175	606.00
IUUC-Pab-098177	Pongo abelii	99.55	0.00e+00	865.00
IUUC-Pca-100734	Procavia capensis	93.03	0.00e+00	834.00
IUUC-Ppe-101272	Prunus persica	44.83	3.00e-10	59.70
IUUC-Pva-102778	Pteropus vampyrus	97.12	0.00e+00	822.00
IUUC-Rno-106039	Rattus norvegicus	96.18	0.00e+00	843.00
IUUC-Sha-106869	Sarcophilus harrisii	94.47	0.00e+00	800.00
IUUC-Sar-113587	Sorex araneus	65.14	9.00e-148	516.00
IUUC-Ssc-116212	Sus scrofa	95.96	0.00e+00	841.00
IUUC-Tgu-116871	Taeniopygia guttata	91.37	0.00e+00	759.00
IUUC-Tru-117925	Takifugu rubripes	72.99	0.00e+00	673.00
IUUC-Tsy-118815	Tarsius syrichta	95.67	0.00e+00	792.00
IUUC-Tni-120007	Tetraodon nigroviridis	73.42	0.00e+00	640.00
IUUC-Tbe-127381	Tupaia belangeri	93.75	0.00e+00	661.00
IUUC-Ttr-129025	Tursiops truncatus	81.01	0.00e+00	646.00
IUUC-Vpa-130164	Vicugna pacos	91.44	2.00e-148	518.00
IUUC-Xtr-132800	Xenopus tropicalis	82.70	0.00e+00	742.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence