iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062986

UUCD1 version

UUC-MoD-00750

Ensembl Protein ID

ENSMODP00000023892.3

UniProt Accession

F7EC98; F7EC98_MONDO

Protein Name

Uncharacterized protein

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000019143.3	ENSMODT00000024316.3	ENSMODP00000023892.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	81.54	2.00e-169	592.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MISSGNGFGV PSCRNWRELA FCLGNVMKQA KPGLTMWATC CNWFCQDGHS EEIQLPQGAR 60
TQAYSNPGYS SFPSPTGSEP SCKSCGAHFG STTRKHTCLD CKKNFCISCS SQVGSGACLC 120

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Nucleotide Sequence
(Fasta)

CACTTTTCCT GAAAGCTGCT GCAATTGGTT CCTGAGATGA TCTCATCTGG AAATGGCTTT 60
GGTGTCCCCA GCTGCAGGAA TTGGAGGGAG CTCGCTTTCT GCTTGGGCAA TGTTATGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

mdo:100018074

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	77.81	1.00e-155	542.00
IUUC-Apl-004124	Anas platyrhynchos	67.30	4.00e-125	441.00
IUUC-Aly-005548	Arabidopsis lyrata	35.90	5.00e-09	56.60
IUUC-Ame-011616	Astyanax mexicanus	57.49	8.00e-104	370.00
IUUC-Bta-012374	Bos taurus	78.36	1.00e-160	558.00
IUUC-Cja-019780	Callithrix jacchus	79.95	2.00e-166	578.00
IUUC-Cfa-021252	Canis familiaris	78.63	4.00e-155	540.00
IUUC-Cpo-022047	Cavia porcellus	78.47	2.00e-162	565.00
IUUC-Csa-023161	Chlorocebus sabaeus	81.54	1.00e-177	615.00
IUUC-Cho-024316	Choloepus hoffmanni	80.86	2.00e-134	471.00
IUUC-Dre-028596	Danio rerio	56.95	4.00e-110	390.00
IUUC-Dno-029333	Dasypus novemcinctus	82.92	1.00e-165	575.00
IUUC-Ete-033163	Echinops telfairi	76.31	3.00e-148	517.00
IUUC-Eca-033994	Equus caballus	78.90	5.00e-164	570.00
IUUC-Eeu-035162	Erinaceus europaeus	75.67	2.00e-108	384.00
IUUC-Fca-036418	Felis catus	79.84	3.00e-175	607.00
IUUC-Fal-037427	Ficedula albicollis	68.22	3.00e-135	474.00
IUUC-Gga-041053	Gallus gallus	69.42	1.00e-135	476.00
IUUC-Ggo-045436	Gorilla gorilla	81.54	6.00e-178	616.00
IUUC-Hsa-045798	Homo sapiens	81.54	6.00e-178	616.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	75.69	9.00e-164	569.00
IUUC-Lch-050639	Latimeria chalumnae	61.98	1.00e-121	429.00
IUUC-Laf-053355	Loxodonta africana	79.89	9.00e-157	546.00
IUUC-Mcc-055222	Macaca mulatta	80.72	2.00e-164	571.00
IUUC-Meu-056692	Macropus eugenii	90.63	0.00e+00	629.00
IUUC-Mga-059298	Meleagris gallopavo	68.77	4.00e-135	474.00
IUUC-Mmr-061792	Microcebus murinus	78.24	6.00e-158	550.00
IUUC-Mmu-063356	Mus musculus	76.38	5.00e-171	593.00
IUUC-Mpu-066273	Mustela putorius furo	77.93	8.00e-171	592.00
IUUC-Mlu-066953	Myotis lucifugus	79.73	3.00e-168	584.00
IUUC-Nle-070075	Nomascus leucogenys	80.27	7.00e-177	612.00
IUUC-Opr-070838	Ochotona princeps	79.61	3.00e-162	564.00
IUUC-Ont-071967	Oreochromis niloticus	49.04	6.00e-87	313.00
IUUC-Ocu-074807	Oryctolagus cuniculus	78.63	4.00e-171	593.00
IUUC-Obr-076159	Oryza brachyantha	36.49	2.00e-08	51.20
IUUC-Ola-086903	Oryzias latipes	46.45	1.00e-88	319.00
IUUC-Oga-088536	Otolemur garnettii	78.79	9.00e-155	539.00
IUUC-Oar-089838	Ovis aries	76.16	1.00e-154	539.00
IUUC-Ptr-090962	Pan troglodytes	81.82	4.00e-178	617.00
IUUC-Pan-092853	Papio anubis	80.72	3.00e-176	610.00
IUUC-Psi-093164	Pelodiscus sinensis	67.40	7.00e-129	453.00
IUUC-Pma-094104	Petromyzon marinus	44.69	1.00e-54	206.00
IUUC-Pab-098304	Pongo abelii	81.10	4.00e-178	617.00
IUUC-Pca-100316	Procavia capensis	81.27	6.00e-154	536.00
IUUC-Ppe-101490	Prunus persica	38.57	2.00e-08	53.90
IUUC-Pva-102612	Pteropus vampyrus	68.04	2.00e-133	468.00
IUUC-Rno-105449	Rattus norvegicus	79.89	3.00e-164	571.00
IUUC-Sha-107578	Sarcophilus harrisii	90.62	0.00e+00	640.00
IUUC-Sit-110649	Setaria italica	36.25	1.00e-09	55.50
IUUC-Sar-113638	Sorex araneus	76.03	2.00e-149	521.00
IUUC-Ssc-116401	Sus scrofa	79.08	3.00e-172	597.00
IUUC-Tru-118765	Takifugu rubripes	49.45	2.00e-82	298.00
IUUC-Tsy-118850	Tarsius syrichta	76.57	5.00e-127	446.00
IUUC-Tbe-128086	Tupaia belangeri	73.28	2.00e-154	538.00
IUUC-Ttr-128249	Tursiops truncatus	62.81	2.00e-119	422.00
IUUC-Vpa-130816	Vicugna pacos	79.07	4.00e-36	144.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence