iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-018794

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACFV01021205

Gene Name

RNF125

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000020872.1	ENSCJAT00000041022.1	ENSCJAP00000038835.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.10e-09	36.7	37	76
E3 activity/RING/U-box	2.20e-09	38.2	33	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C++Cle + + p+ ++CgHvf+++C+   +      ++++++CP+Cr
   Q: 37   CSVCLEVLHR-PVRTRCGHVFCRSCIaTSL------KNNKWTCPYCR 76
           **********.777***********95555......**********8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawc 69
             f C++ le+ + Pv + +G+++ rs+I+  l++++ tcP +r+ l +  +    + +r+ +++ 
   Q: 33   TSFDCSVCLEVLHRPVRTRCGHVFCRSCIATSLKNNKWTCPYCRAYLPSGGVPATDVAKRMKSEFK 98
           579******************************99999*********9999999999999999885 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MGSVLSSDSG KSAPASATPR ALEHRGDPEL PVTSFDCSVC LEVLHRPVRT RCGHVFCRSC 60
IATSLKNNKW TCPYCRAYLP SGGVPATDVA KRMKSEFKNC TECNTLVCLS EMRAHIRTCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTCTGACT GTGGGGAAAG AGGTTGTGTG GGTGACAGCT TGGAAGGTTT ACTACTGCCT 60
CAATCCTCTT TTCTGCAGTT GAGGTTTCAG GTTTCAATCC TCCCAATACC ACAAGACAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008598--Di19_Zn_binding_dom
IPR034734--ZF_C2HC_RNF
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51803--ZF_C2HC_RNF
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF05605--zf-Di19

SMART

SM00184--RING

Gene Ontology

GO:0000139--C:Golgi membrane
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

cjc:100386104

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001992	Ailuropoda melanoleuca	91.81	2.00e-127	447.00
IUUC-Aca-004839	Anolis carolinensis	62.57	1.00e-66	245.00
IUUC-Bta-012827	Bos taurus	90.95	7.00e-126	442.00
IUUC-Cfa-021234	Canis familiaris	90.95	4.00e-117	413.00
IUUC-Cpo-022412	Cavia porcellus	78.45	3.00e-104	370.00
IUUC-Csa-023406	Chlorocebus sabaeus	93.97	8.00e-129	452.00
IUUC-Cho-024427	Choloepus hoffmanni	75.14	7.00e-74	269.00
IUUC-Dno-030085	Dasypus novemcinctus	91.38	2.00e-126	444.00
IUUC-Dor-030911	Dipodomys ordii	70.26	1.00e-76	279.00
IUUC-Ete-032469	Echinops telfairi	84.91	1.00e-117	415.00
IUUC-Eca-034352	Equus caballus	92.67	1.00e-127	448.00
IUUC-Eeu-034889	Erinaceus europaeus	77.16	5.00e-101	360.00
IUUC-Fca-036116	Felis catus	91.38	5.00e-119	419.00
IUUC-Hsa-046518	Homo sapiens	93.53	8.00e-128	449.00
IUUC-Itr-048344	Ictidomys tridecemlineatus	94.35	5.00e-99	352.00
IUUC-Laf-053363	Loxodonta africana	91.03	1.00e-125	441.00
IUUC-Meu-056101	Macropus eugenii	78.20	9.00e-96	342.00
IUUC-Mdo-062046	Monodelphis domestica	74.68	5.00e-99	353.00
IUUC-Mmu-063184	Mus musculus	84.29	2.00e-58	217.00
IUUC-Mpu-065708	Mustela putorius furo	89.66	3.00e-124	437.00
IUUC-Mlu-067561	Myotis lucifugus	89.27	7.00e-94	335.00
IUUC-Nle-069665	Nomascus leucogenys	92.99	2.00e-117	414.00
IUUC-Opr-070301	Ochotona princeps	78.45	3.00e-104	370.00
IUUC-Ocu-074562	Oryctolagus cuniculus	92.06	2.00e-66	243.00
IUUC-Oga-088958	Otolemur garnettii	91.81	4.00e-127	446.00
IUUC-Oar-089541	Ovis aries	90.96	3.00e-96	343.00
IUUC-Ptr-090989	Pan troglodytes	93.97	8.00e-129	452.00
IUUC-Pan-092372	Papio anubis	93.97	4.00e-129	453.00
IUUC-Pab-098718	Pongo abelii	79.74	5.00e-103	366.00
IUUC-Pca-100453	Procavia capensis	89.22	1.00e-122	431.00
IUUC-Pva-102931	Pteropus vampyrus	91.38	5.00e-118	416.00
IUUC-Rno-105771	Rattus norvegicus	87.26	1.00e-99	355.00
IUUC-Sha-107557	Sarcophilus harrisii	75.54	9.00e-107	379.00
IUUC-Sar-113435	Sorex araneus	92.06	5.00e-67	245.00
IUUC-Ssc-116388	Sus scrofa	93.10	2.00e-128	451.00
IUUC-Tsy-119439	Tarsius syrichta	93.22	9.00e-98	348.00
IUUC-Tbe-127417	Tupaia belangeri	66.67	5.00e-70	256.00
IUUC-Ttr-129212	Tursiops truncatus	93.10	1.00e-128	451.00
IUUC-Vpa-130153	Vicugna pacos	90.52	9.00e-125	438.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence