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Tag Content
iUUCD ID IUUC-Nfi-068411
Ensembl Protein ID CADNFIAP00009077
UniProt Accession A1DBH2; MYO1_NEOFI
Genbank Protein ID EAW20212.1
Protein Name Myosin-1; Class I unconventional myosin; Type I myosin
Genbank Nucleotide ID DS027694
Gene Name NFIA_098420; myoA
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
CADNFIAG00009291 CADNFIAT00009291 CADNFIAP00009077
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 5.10e-12 44.7 1080 1134
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           + +vlyd+++q+++eL++k+G++v+++   ++ +gW+ + + ++  +G  Pe + e+
   Q: 1080 TAKVLYDFNSQQSNELSIKAGEIVQIV--SKEGNGWWLCMNMTTSAQGWTPEAYLEE 1134
           679************************..67788******************99875 PP
   
Organism Neosartorya fischeri
Functional Description
(View)

Functional Description


     Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity).
 Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity).
Protein Sequence
(Fasta)
MGHSRRPAGG EKKSRGFGRS KAAADVGDGR QTGGKPQVKK ATFESTKKKE IGVSDLTLLS 60
KISNEAINDN LKLRFEHDEI YTYIGHVLVS VNPFQDLGIY TDNVLQSYRG KNRLEVPPHV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Nfi-068411|UBD,SH3|Neosartorya fischeri
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGTATGTC TACAATTAAC CCACACAATC AGCTTCAGAG GAAATTGTTC TTGATTCAGA 60
AATTGTTTTT CTAACTCCGC GCTTTCTTCT AGGGACACTC ACGACGTCCT GCTGGCGGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Nfi-068411|UBD,SH3|Neosartorya fischeri
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0009--Actin-binding
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0378--Hydrolase
KW-0505--Motor protein
KW-0518--Myosin
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain
Interpro

IPR001609--Myosin_head_motor_dom
IPR010926--Myosin_TH1
IPR027417--P-loop_NTPase
IPR001452--SH3_domain
PROSITE

PS51456--MYOSIN_MOTOR
PS50002--SH3
PS51757--TH1
Pfam

PF00063--Myosin_head
PF06017--Myosin_TH1
PF00018--SH3_1
PRINTS

PR00193--MYOSINHEAVY
SMART

SM00242--MYSc
SM00326--SH3
Gene Ontology

GO:0030479--C:actin cortical patch
GO:0016459--C:myosin complex
GO:0005524--F:ATP binding
GO:0003774--F:motor activity
KEGG nfi:NFIA_098420
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002158 Ailuropoda melanoleuca 43.77 0.00e+00 750.00
IUUC-Apl-003803 Anas platyrhynchos 43.82 0.00e+00 757.00
IUUC-Aca-004926 Anolis carolinensis 42.51 0.00e+00 711.00
IUUC-Acl-008168 Aspergillus clavatus 92.67 0.00e+00 2113.00
IUUC-Afl-008552 Aspergillus flavus 86.79 0.00e+00 2040.00
IUUC-Afu-008958 Aspergillus fumigatus 96.56 0.00e+00 2201.00
IUUC-Ang-009818 Aspergillus niger 92.41 0.00e+00 1899.00
IUUC-Aor-009891 Aspergillus oryzae 86.63 0.00e+00 2036.00
IUUC-Ate-010325 Aspergillus terreus 91.27 0.00e+00 1881.00
IUUC-Ame-011036 Astyanax mexicanus 40.41 0.00e+00 780.00
IUUC-Bta-012409 Bos taurus 43.28 0.00e+00 761.00
IUUC-Cel-018582 Caenorhabditis elegans 40.68 0.00e+00 701.00
IUUC-Cja-019330 Callithrix jacchus 38.78 0.00e+00 734.00
IUUC-Cfa-020409 Canis familiaris 43.33 0.00e+00 754.00
IUUC-Cpo-021332 Cavia porcellus 43.79 0.00e+00 769.00
IUUC-Csa-023357 Chlorocebus sabaeus 43.29 0.00e+00 736.00
IUUC-Dre-027800 Danio rerio 44.79 0.00e+00 761.00
IUUC-Dno-029858 Dasypus novemcinctus 39.74 0.00e+00 743.00
IUUC-Dor-030253 Dipodomys ordii 40.41 6.00e-170 590.00
IUUC-Dse-031169 Dothistroma septosporum 45.10 5.00e-09 56.20
IUUC-Eca-034303 Equus caballus 43.17 0.00e+00 698.00
IUUC-Eeu-034561 Erinaceus europaeus 37.76 2.00e-49 189.00
IUUC-Fca-036174 Felis catus 40.91 0.00e+00 674.00
IUUC-Fal-037393 Ficedula albicollis 43.41 0.00e+00 751.00
IUUC-Gmo-038566 Gadus morhua 40.77 0.00e+00 660.00
IUUC-Ggr-040112 Gaeumannomyces graminis 32.69 2.00e-05 43.50
IUUC-Gga-040323 Gallus gallus 44.42 0.00e+00 761.00
IUUC-Gac-042415 Gasterosteus aculeatus 43.92 0.00e+00 716.00
IUUC-Ggo-044547 Gorilla gorilla 42.99 0.00e+00 737.00
IUUC-Hsa-045712 Homo sapiens 43.93 0.00e+00 764.00
IUUC-Itr-048108 Ictidomys tridecemlineatus 42.65 0.00e+00 732.00
IUUC-Lch-050042 Latimeria chalumnae 39.19 0.00e+00 717.00
IUUC-Loc-052303 Lepisosteus oculatus 44.02 0.00e+00 764.00
IUUC-Laf-054148 Loxodonta africana 39.32 0.00e+00 738.00
IUUC-Mcc-054773 Macaca mulatta 43.18 0.00e+00 765.00
IUUC-Meu-056504 Macropus eugenii 39.60 2.00e-83 302.00
IUUC-Mor-057154 Magnaporthe oryzae 30.77 7.00e-05 41.60
IUUC-Mpo-057499 Magnaporthe poae 34.62 8.00e-06 44.70
IUUC-Mga-059294 Meleagris gallopavo 30.77 2.00e-15 75.10
IUUC-Mmr-061357 Microcebus murinus 45.56 0.00e+00 760.00
IUUC-Mdo-062467 Monodelphis domestica 42.51 0.00e+00 756.00
IUUC-Mmu-063711 Mus musculus 43.21 0.00e+00 761.00
IUUC-Mpu-066658 Mustela putorius furo 43.78 0.00e+00 764.00
IUUC-Mlu-067569 Myotis lucifugus 41.51 9.00e-09 54.30
IUUC-Ncr-068956 Neurospora crassa 32.69 3.00e-05 42.70
IUUC-Nle-070144 Nomascus leucogenys 43.12 0.00e+00 736.00
IUUC-Ont-071404 Oreochromis niloticus 42.96 0.00e+00 726.00
IUUC-Oan-073284 Ornithorhynchus anatinus 28.73 6.00e-23 100.00
IUUC-Ola-087396 Oryzias latipes 39.96 0.00e+00 768.00
IUUC-Oga-088985 Otolemur garnettii 44.64 0.00e+00 761.00
IUUC-Oar-089527 Ovis aries 39.02 0.00e+00 719.00
IUUC-Ptr-090485 Pan troglodytes 42.99 0.00e+00 736.00
IUUC-Pan-092029 Papio anubis 43.18 0.00e+00 765.00
IUUC-Psi-094016 Pelodiscus sinensis 33.40 1.00e-135 476.00
IUUC-Pma-094458 Petromyzon marinus 43.76 0.00e+00 750.00
IUUC-Pfo-096486 Poecilia formosa 43.01 0.00e+00 730.00
IUUC-Pab-098517 Pongo abelii 42.71 0.00e+00 721.00
IUUC-Pca-100128 Procavia capensis 34.56 1.00e-68 253.00
IUUC-Pva-102994 Pteropus vampyrus 41.84 0.00e+00 693.00
IUUC-Rno-105992 Rattus norvegicus 43.47 0.00e+00 763.00
IUUC-Sha-107424 Sarcophilus harrisii 42.43 0.00e+00 748.00
IUUC-Ssc-115400 Sus scrofa 43.93 0.00e+00 766.00
IUUC-Tgu-116572 Taeniopygia guttata 39.35 0.00e+00 696.00
IUUC-Tru-117568 Takifugu rubripes 42.80 0.00e+00 721.00
IUUC-Tni-120087 Tetraodon nigroviridis 39.59 0.00e+00 744.00
IUUC-Tre-122048 Trichoderma reesei 65.59 0.00e+00 1477.00
IUUC-Tbe-127462 Tupaia belangeri 35.80 9.00e-106 376.00
IUUC-Ttr-128783 Tursiops truncatus 39.93 0.00e+00 735.00
IUUC-Vda-130020 Verticillium dahliae 67.99 0.00e+00 1457.00
IUUC-Xtr-131936 Xenopus tropicalis 42.58 0.00e+00 728.00
IUUC-Xma-133052 Xiphophorus maculatus 44.16 0.00e+00 719.00
Created Date 25-Jun-2017

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