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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046830
UUCD1 version UUC-HoS-00741
Ensembl Protein ID ENSP00000274811.4
UniProt Accession Q7L0R7; B4DYE0; Q8ND05; Q9UPQ2; RNF44_HUMAN
Genbank Protein ID BAA83052.2; BAG63702.1; AAH39833.1; AAH63297.1; CAD39147.2
Protein Name RING finger protein 44
Genbank Nucleotide ID AB029023; AK302385; AC010316; BC063297; AL834489
Gene Name RNF44; KIAA1100
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000146083.11 ENST00000274811.8 ENSP00000274811.4
ENSG00000146083.11 ENST00000506378.1 ENSP00000425253.1
ENSG00000146083.11 ENST00000513029.5 ENSP00000427604.1
ENSG00000146083.11 ENST00000504160.1 ENSP00000424699.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
miRTarBasemicroRNATRANSFACTargetScan
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
Mentha
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
CPLMPhosphositePlusdbPTMBioGRID
mUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 5.90e-09 38.0 380 421
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +C++df+    ++vlpC+H fh++C+ kw       + + +CP+Cr
   Q: 380  CVVCFSDFEARqlLRVLPCNHEFHTKCVDKW------LKANRTCPICR 421
           ********5545699****************......**********8 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MRPWALAVTR WPPSAPVGQR RFSAGPGSTP GQLWGSPGLE GPLASPPARD ERLPSQQPPS 60
RPPHLPVEER RASAPAGGSP RMLHPATQQS PFMVDLHEQV HQGPVPLSYT VTTVTTQGFP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046830|E3,RING|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGACGTTAGC TCGTTTGCAT GGGTGGTCCG CCATTGGTCT GTTGGGCAAT CTGGGCCGTA 60
CCAGCTTTTT AAAGACGCCG TGTAGTATAA ACAAGGAGAA GTGGGGCGGC CGGGCCATGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046830|E3,RING|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF13639--zf-RING_2
SMART

SM00184--RING
Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
KEGG hsa:22838
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001093 Aegilops tauschii 30.83 1.00e-15 77.80
IUUC-Aml-002180 Ailuropoda melanoleuca 90.97 0.00e+00 669.00
IUUC-Aca-004353 Anolis carolinensis 74.05 4.00e-155 541.00
IUUC-Aly-005825 Arabidopsis lyrata 40.00 6.00e-14 71.60
IUUC-Ath-007389 Arabidopsis thaliana 40.00 6.00e-14 71.60
IUUC-Ame-011569 Astyanax mexicanus 65.78 7.00e-131 460.00
IUUC-Bta-012954 Bos taurus 93.29 0.00e+00 702.00
IUUC-Bol-015622 Brassica oleracea 40.00 2.00e-13 70.10
IUUC-Bra-017837 Brassica rapa 40.00 5.00e-14 71.60
IUUC-Cja-019606 Callithrix jacchus 94.87 4.00e-171 593.00
IUUC-Cfa-020959 Canis familiaris 93.89 0.00e+00 710.00
IUUC-Cpo-022130 Cavia porcellus 91.90 0.00e+00 731.00
IUUC-Cre-022984 Chlamydomonas reinhardtii 33.68 3.00e-12 68.20
IUUC-Csa-024265 Chlorocebus sabaeus 98.15 0.00e+00 733.00
IUUC-Dno-030071 Dasypus novemcinctus 93.94 0.00e+00 693.00
IUUC-Dor-030199 Dipodomys ordii 80.32 5.00e-175 607.00
IUUC-Eca-034105 Equus caballus 95.37 0.00e+00 691.00
IUUC-Fca-036360 Felis catus 95.60 0.00e+00 710.00
IUUC-Fal-037494 Ficedula albicollis 77.65 2.00e-168 585.00
IUUC-Gmo-038772 Gadus morhua 63.15 1.00e-130 459.00
IUUC-Gga-040521 Gallus gallus 77.43 1.00e-167 582.00
IUUC-Gac-041636 Gasterosteus aculeatus 65.84 3.00e-129 455.00
IUUC-Gma-042757 Glycine max 47.22 1.00e-15 77.00
IUUC-Ggo-044732 Gorilla gorilla 95.60 0.00e+00 709.00
IUUC-Itr-048694 Ictidomys tridecemlineatus 95.61 0.00e+00 687.00
IUUC-Lch-050227 Latimeria chalumnae 72.91 4.00e-153 534.00
IUUC-Loc-052302 Lepisosteus oculatus 68.82 1.00e-142 499.00
IUUC-Laf-053419 Loxodonta africana 85.42 0.00e+00 669.00
IUUC-Mcc-054969 Macaca mulatta 98.58 9.00e-179 619.00
IUUC-Meu-056404 Macropus eugenii 82.57 0.00e+00 647.00
IUUC-Mla-058928 Melampsora laricipopulina 39.39 4.00e-10 58.20
IUUC-Mdo-062309 Monodelphis domestica 87.10 3.00e-154 538.00
IUUC-Mmu-063712 Mus musculus 89.84 0.00e+00 671.00
IUUC-Mac-065494 Musa acuminata 49.28 4.00e-15 75.90
IUUC-Mpu-066508 Mustela putorius furo 96.03 0.00e+00 696.00
IUUC-Mlu-068210 Myotis lucifugus 92.38 0.00e+00 642.00
IUUC-Nle-069124 Nomascus leucogenys 96.30 0.00e+00 716.00
IUUC-Opr-071167 Ochotona princeps 91.32 6.00e-160 556.00
IUUC-Ont-072090 Oreochromis niloticus 64.56 1.00e-121 429.00
IUUC-Ocu-074801 Oryctolagus cuniculus 74.72 7.00e-160 556.00
IUUC-Oba-075724 Oryza barthii 34.96 1.00e-15 78.20
IUUC-Obr-076624 Oryza brachyantha 31.71 3.00e-15 76.60
IUUC-Ogl-077689 Oryza glaberrima 34.96 1.00e-15 78.20
IUUC-Ogu-078097 Oryza glumaepatula 37.29 4.00e-17 82.40
IUUC-Oin-079530 Oryza indica 34.96 9.00e-16 78.20
IUUC-Olo-080582 Oryza longistaminata 35.71 9.00e-16 78.20
IUUC-Ome-081876 Oryza meridionalis 34.65 6.00e-16 79.00
IUUC-Oni-082354 Oryza nivara 34.96 1.00e-15 78.20
IUUC-Opu-084138 Oryza punctata 35.64 2.00e-15 77.00
IUUC-Oru-085113 Oryza rufipogon 34.96 1.00e-15 78.20
IUUC-Osa-085539 Oryza sativa 34.96 1.00e-15 78.20
IUUC-Ola-086948 Oryzias latipes 66.59 5.00e-127 447.00
IUUC-Oga-087987 Otolemur garnettii 94.31 0.00e+00 724.00
IUUC-Oar-089245 Ovis aries 89.75 0.00e+00 681.00
IUUC-Ptr-091155 Pan troglodytes 99.54 0.00e+00 746.00
IUUC-Pan-092597 Papio anubis 98.84 0.00e+00 746.00
IUUC-Pfo-096747 Poecilia formosa 67.27 2.00e-126 445.00
IUUC-Pab-098133 Pongo abelii 87.39 8.00e-159 552.00
IUUC-Pca-100961 Procavia capensis 89.81 0.00e+00 682.00
IUUC-Ppe-102055 Prunus persica 38.89 5.00e-16 78.60
IUUC-Pva-102987 Pteropus vampyrus 89.35 0.00e+00 642.00
IUUC-Rno-105434 Rattus norvegicus 93.18 1.00e-164 572.00
IUUC-Sha-107023 Sarcophilus harrisii 75.74 9.00e-172 596.00
IUUC-Sit-109970 Setaria italica 44.00 6.00e-15 75.10
IUUC-Sar-113463 Sorex araneus 82.70 2.00e-131 461.00
IUUC-Sbi-114529 Sorghum bicolor 45.33 1.00e-15 77.40
IUUC-Ssc-115578 Sus scrofa 95.83 0.00e+00 715.00
IUUC-Tgu-117430 Taeniopygia guttata 77.88 5.00e-164 570.00
IUUC-Tru-117715 Takifugu rubripes 67.19 1.00e-131 462.00
IUUC-Tni-119691 Tetraodon nigroviridis 66.74 2.00e-131 462.00
IUUC-Tae-123235 Triticum aestivum 31.90 1.00e-15 77.80
IUUC-Tbe-127519 Tupaia belangeri 87.08 4.00e-142 497.00
IUUC-Ttr-128179 Tursiops truncatus 95.60 0.00e+00 722.00
IUUC-Xtr-132852 Xenopus tropicalis 71.43 1.00e-145 509.00
IUUC-Xma-133465 Xiphophorus maculatus 64.56 4.00e-122 431.00
Created Date 25-Jun-2017

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