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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064068
Ensembl Protein ID ENSMUSP00000136867.1
UniProt Accession Q8K3J5; Q3UYZ4; Q80UU7; Q8C8D0; Q9D042; ZN131_MOUSE
Genbank Protein ID AAM18207.1; BAB27867.1; BAC26943.1; BAC33056.1; BAE22067.1; BAE22629.1; BAE37106.1; AAH48839.1; AAH57991.1
Protein Name Zinc finger protein 131
Genbank Nucleotide ID AY092766; AK011832; AK030398; AK047429; AK134257; AK135723; AK162903; BC048839; BC057991
Gene Name Zfp131; Znf131
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000094870.7 ENSMUST00000177916.7 ENSMUSP00000136867.1
ENSMUSG00000094870.7 ENSMUST00000178271.1 ENSMUSP00000136019.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
miRTarBasemicroRNATRANSFACRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
UniProt
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 1.50e-14 55.2 34 95
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +D++l+v+g +f+ahk+vLaa+S++Fy+ f +e+ +   ++ vei++v+  +fr+l++F Yt kl 
   Q: 34   TDITLIVDGHHFKAHKAVLAACSKFFYKFF-QEFTQ---EPLVEIEGVSKMAFRHLIEFTYTAKLM 95
           79****************************.66664...589*********************996 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling (By similarity). Plays a role during development and organogenesis as well as in the function of the adult central nervous system.
 May be involved in transcriptional regulation as a repressor of ESR1/ER-alpha signaling (By similarity). Plays a role during development and organogenesis as well as in the function of the adult central nervous system.
Protein Sequence
(Fasta)
MEAEETMECL QEFPEHHKMI LDRLNEQREQ DRFTDITLIV DGHHFKAHKA VLAACSKFFY 60
KFFQEFTQEP LVEIEGVSKM AFRHLIEFTY TAKLMIQGEE EANDVWKAAE FLQMLEAIKA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064068|E3,BTB_Other|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCCCCGGGC CGCTCCTCCT TCCCTGAGTG AGTGCCGGCC GGGTCGGGGC GGGGGGGGGG 60
GGGGGGTAGA GGAGGGAGAG GCGCCGGAGG GAGAGGCGAC CCGGGGAGTC GTTGTGGGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064068|E3,BTB_Other|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000210--BTB/POZ_dom
IPR027775--C2H2_Znf_fam_sub
IPR023413--GFP-like
IPR011333--SKP1/BTB/POZ
IPR027758--Zfp131
IPR013087--Znf_C2H2_type
PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00651--BTB
SMART

SM00225--BTB
SM00355--ZnF_C2H2
Gene Ontology

GO:0045111--C:intermediate filament cytoskeleton
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0006351--P:transcription, DNA-templated
KEGG mmu:72465
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001514 Ailuropoda melanoleuca 92.06 0.00e+00 1087.00
IUUC-Apl-004058 Anas platyrhynchos 86.18 0.00e+00 689.00
IUUC-Aca-005161 Anolis carolinensis 72.28 0.00e+00 862.00
IUUC-Ame-011414 Astyanax mexicanus 54.99 3.00e-131 462.00
IUUC-Cja-018767 Callithrix jacchus 93.42 0.00e+00 1083.00
IUUC-Cfa-021094 Canis familiaris 92.49 0.00e+00 1093.00
IUUC-Cpo-022314 Cavia porcellus 85.33 0.00e+00 1003.00
IUUC-Csa-023639 Chlorocebus sabaeus 87.96 0.00e+00 1045.00
IUUC-Cho-024503 Choloepus hoffmanni 90.71 0.00e+00 1064.00
IUUC-Dre-028729 Danio rerio 62.42 6.00e-150 524.00
IUUC-Dno-029405 Dasypus novemcinctus 91.87 0.00e+00 1047.00
IUUC-Eca-033617 Equus caballus 86.51 0.00e+00 950.00
IUUC-Fca-036293 Felis catus 85.19 0.00e+00 976.00
IUUC-Fal-037260 Ficedula albicollis 73.29 0.00e+00 816.00
IUUC-Gmo-038585 Gadus morhua 58.23 2.00e-150 525.00
IUUC-Gga-040803 Gallus gallus 80.36 0.00e+00 961.00
IUUC-Gac-041656 Gasterosteus aculeatus 56.78 2.00e-149 522.00
IUUC-Ggo-045484 Gorilla gorilla 93.10 0.00e+00 1102.00
IUUC-Hsa-046829 Homo sapiens 93.26 0.00e+00 1102.00
IUUC-Itr-048719 Ictidomys tridecemlineatus 93.88 0.00e+00 1084.00
IUUC-Lch-049844 Latimeria chalumnae 65.22 0.00e+00 759.00
IUUC-Laf-053393 Loxodonta africana 89.26 0.00e+00 1031.00
IUUC-Mcc-055008 Macaca mulatta 88.12 0.00e+00 1048.00
IUUC-Meu-056284 Macropus eugenii 84.96 0.00e+00 896.00
IUUC-Mmr-060917 Microcebus murinus 81.54 0.00e+00 927.00
IUUC-Mdo-062737 Monodelphis domestica 81.07 0.00e+00 840.00
IUUC-Mpu-066880 Mustela putorius furo 92.96 0.00e+00 1100.00
IUUC-Mlu-067817 Myotis lucifugus 89.23 0.00e+00 1009.00
IUUC-Nle-069781 Nomascus leucogenys 92.94 0.00e+00 1100.00
IUUC-Ont-071713 Oreochromis niloticus 58.73 1.00e-147 516.00
IUUC-Ocu-074381 Oryctolagus cuniculus 87.62 0.00e+00 1032.00
IUUC-Ola-086936 Oryzias latipes 52.90 6.00e-151 527.00
IUUC-Oga-088696 Otolemur garnettii 63.33 2.00e-136 478.00
IUUC-Oar-090187 Ovis aries 93.27 0.00e+00 1096.00
IUUC-Ptr-091077 Pan troglodytes 87.64 0.00e+00 1014.00
IUUC-Pan-091830 Papio anubis 88.12 0.00e+00 1048.00
IUUC-Psi-093902 Pelodiscus sinensis 75.33 0.00e+00 892.00
IUUC-Pma-094410 Petromyzon marinus 40.45 5.00e-103 368.00
IUUC-Pfo-096471 Poecilia formosa 55.33 1.00e-148 520.00
IUUC-Pab-097728 Pongo abelii 87.48 0.00e+00 988.00
IUUC-Pca-100437 Procavia capensis 94.24 1.00e-155 543.00
IUUC-Pva-102195 Pteropus vampyrus 83.79 0.00e+00 927.00
IUUC-Rno-105640 Rattus norvegicus 96.45 0.00e+00 1169.00
IUUC-Sha-107212 Sarcophilus harrisii 80.91 0.00e+00 870.00
IUUC-Ssc-115860 Sus scrofa 100.00 4.00e-45 171.00
IUUC-Tgu-116547 Taeniopygia guttata 79.87 0.00e+00 940.00
IUUC-Tru-117534 Takifugu rubripes 59.06 6.00e-152 530.00
IUUC-Tni-120102 Tetraodon nigroviridis 59.33 4.00e-150 524.00
IUUC-Ttr-128199 Tursiops truncatus 95.87 0.00e+00 1036.00
IUUC-Vpa-130705 Vicugna pacos 95.59 0.00e+00 1038.00
IUUC-Xtr-132306 Xenopus tropicalis 70.00 0.00e+00 711.00
Created Date 25-Jun-2017

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