iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073409

UUCD1 version

UUC-OrA-00013

Ensembl Protein ID

ENSOANP00000001475.1

UniProt Accession

F6PJK3; F6PJK3_ORNAN

Protein Name

Uncharacterized protein

Gene Name

RFWD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000000942.2	ENSOANT00000001476.2	ENSOANP00000001475.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.80e-06	26.4	1	38
E3 adaptor/Cullin RING/DCX/DWD	6.50e-22	76.9	334	363

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 2    aiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           +iC++++++  + + CgH f+ +C+++          + rCP C+
   Q: 1    PICFDMIEE-AYMTKCGHSFCYKCIHQS------LEDNNRCPKCN 38
           8******99.888***********9555......999999****6 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +++++c+++     +ll+s+ + gt+ +WD
   Q: 334  NSKISCISWssYHkNLLASSDYEGTVILWD 363
           689******9622599************** PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

PICFDMIEEA YMTKCGHSFC YKCIHQSLED NNRCPKCNYV VDNIDHLYPN FLVNELILKQ 60
KQRFEEKRFK LDHSVSSTNG HRWQIFQDLL GTDQDNLDLA NVNLMLELLV QKKKQLEAES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTAGAAACA TGCCTCTGAT TTTTTCATTT TTTCATTTCC TTTCAGCCCC ATCTGTTTTG 60
ACATGATCGA GGAAGCATAC ATGACGAAAT GTGGCCACAG CTTCTGGTAA GATGGTTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR002469--Peptidase_S9B_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00400--WD40

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000885	Aegilops tauschii	39.58	5.00e-120	424.00
IUUC-Aml-001265	Ailuropoda melanoleuca	98.80	0.00e+00	1161.00
IUUC-Atr-002460	Amborella trichopoda	37.88	5.00e-116	410.00
IUUC-Apl-003796	Anas platyrhynchos	98.63	0.00e+00	1154.00
IUUC-Aca-005078	Anolis carolinensis	97.42	0.00e+00	1127.00
IUUC-Aly-006014	Arabidopsis lyrata	39.61	9.00e-122	430.00
IUUC-Ath-007636	Arabidopsis thaliana	39.52	3.00e-121	428.00
IUUC-Ame-011176	Astyanax mexicanus	96.69	1.00e-69	256.00
IUUC-Bta-012595	Bos taurus	98.80	0.00e+00	1161.00
IUUC-Bdi-014152	Brachypodium distachyon	38.72	1.00e-120	426.00
IUUC-Bol-016380	Brassica oleracea	40.26	1.00e-122	433.00
IUUC-Bra-017690	Brassica rapa	39.07	2.00e-118	419.00
IUUC-Cja-018926	Callithrix jacchus	98.45	0.00e+00	1155.00
IUUC-Cfa-021088	Canis familiaris	98.45	0.00e+00	1160.00
IUUC-Cpo-022442	Cavia porcellus	96.79	0.00e+00	1154.00
IUUC-Cre-022579	Chlamydomonas reinhardtii	33.33	1.00e-32	132.00
IUUC-Csa-024119	Chlorocebus sabaeus	96.66	0.00e+00	1161.00
IUUC-Cho-024883	Choloepus hoffmanni	86.15	1.00e-86	313.00
IUUC-Cin-025375	Ciona intestinalis	55.93	0.00e+00	637.00
IUUC-Cme-027350	Cyanidioschyzon merolae	45.30	2.00e-73	270.00
IUUC-Dre-028453	Danio rerio	87.24	0.00e+00	1014.00
IUUC-Dno-029887	Dasypus novemcinctus	97.94	0.00e+00	1151.00
IUUC-Dor-031110	Dipodomys ordii	78.65	0.00e+00	885.00
IUUC-Ete-033016	Echinops telfairi	82.99	0.00e+00	944.00
IUUC-Eca-034403	Equus caballus	98.96	0.00e+00	1153.00
IUUC-Eeu-034690	Erinaceus europaeus	83.85	0.00e+00	952.00
IUUC-Fca-036475	Felis catus	98.28	0.00e+00	1155.00
IUUC-Fal-037189	Ficedula albicollis	98.28	0.00e+00	1155.00
IUUC-Gmo-039245	Gadus morhua	86.15	0.00e+00	1000.00
IUUC-Gga-040806	Gallus gallus	98.28	0.00e+00	1155.00
IUUC-Gac-042177	Gasterosteus aculeatus	87.69	0.00e+00	1031.00
IUUC-Gma-044187	Glycine max	40.22	2.00e-118	419.00
IUUC-Ggo-044430	Gorilla gorilla	98.21	0.00e+00	872.00
IUUC-Hsa-045853	Homo sapiens	98.45	0.00e+00	1156.00
IUUC-Hvu-047750	Hordeum vulgare	38.00	6.00e-87	315.00
IUUC-Itr-048238	Ictidomys tridecemlineatus	99.17	3.00e-142	496.00
IUUC-Lch-050420	Latimeria chalumnae	91.34	0.00e+00	1065.00
IUUC-Lpe-051219	Leersia perrieri	38.76	4.00e-119	421.00
IUUC-Loc-052728	Lepisosteus oculatus	90.29	0.00e+00	1031.00
IUUC-Laf-053775	Loxodonta africana	97.77	0.00e+00	1160.00
IUUC-Meu-056595	Macropus eugenii	77.75	2.00e-176	611.00
IUUC-Mtr-058555	Medicago truncatula	40.32	2.00e-125	442.00
IUUC-Mga-059646	Meleagris gallopavo	98.45	0.00e+00	1152.00
IUUC-Mmr-060990	Microcebus murinus	96.66	0.00e+00	1162.00
IUUC-Mdo-062287	Monodelphis domestica	98.80	0.00e+00	1161.00
IUUC-Mmu-064097	Mus musculus	98.45	0.00e+00	1158.00
IUUC-Mac-065240	Musa acuminata	40.89	4.00e-127	447.00
IUUC-Mpu-066612	Mustela putorius furo	98.96	0.00e+00	1159.00
IUUC-Mlu-067967	Myotis lucifugus	98.96	0.00e+00	1154.00
IUUC-Nle-069543	Nomascus leucogenys	98.63	0.00e+00	1160.00
IUUC-Opr-070366	Ochotona princeps	84.33	0.00e+00	674.00
IUUC-Ont-071522	Oreochromis niloticus	87.18	0.00e+00	1018.00
IUUC-Ocu-073756	Oryctolagus cuniculus	98.96	0.00e+00	1157.00
IUUC-Oba-075149	Oryza barthii	38.34	9.00e-119	421.00
IUUC-Obr-076563	Oryza brachyantha	38.72	8.00e-119	420.00
IUUC-Ogl-077701	Oryza glaberrima	38.34	5.00e-119	421.00
IUUC-Ogu-078383	Oryza glumaepatula	38.34	5.00e-119	421.00
IUUC-Oin-079965	Oryza indica	36.21	2.00e-107	382.00
IUUC-Olo-080639	Oryza longistaminata	38.18	6.00e-117	414.00
IUUC-Ome-081821	Oryza meridionalis	38.18	1.00e-108	387.00
IUUC-Oni-082622	Oryza nivara	38.34	5.00e-119	421.00
IUUC-Opu-083295	Oryza punctata	38.34	6.00e-119	421.00
IUUC-Oru-084661	Oryza rufipogon	38.34	5.00e-119	421.00
IUUC-Osa-085766	Oryza sativa	38.34	5.00e-119	421.00
IUUC-Ola-086727	Oryzias latipes	87.35	0.00e+00	1038.00
IUUC-Olu-087702	Ostreococcus lucimarinus	42.96	2.00e-64	238.00
IUUC-Oga-088215	Otolemur garnettii	98.80	0.00e+00	1164.00
IUUC-Oar-089880	Ovis aries	99.48	0.00e+00	1157.00
IUUC-Ptr-090597	Pan troglodytes	98.45	0.00e+00	1156.00
IUUC-Pan-091987	Papio anubis	98.80	0.00e+00	1162.00
IUUC-Psi-094033	Pelodiscus sinensis	97.75	0.00e+00	1135.00
IUUC-Pma-094587	Petromyzon marinus	70.36	0.00e+00	764.00
IUUC-Ppa-095256	Physcomitrella patens	38.74	6.00e-123	434.00
IUUC-Pfo-097388	Poecilia formosa	86.28	0.00e+00	999.00
IUUC-Pab-098029	Pongo abelii	98.45	0.00e+00	1156.00
IUUC-Pop-099319	Populus trichocarpa	38.14	3.00e-121	428.00
IUUC-Pca-100846	Procavia capensis	89.52	0.00e+00	1048.00
IUUC-Ppe-101250	Prunus persica	38.54	1.00e-112	399.00
IUUC-Pva-102407	Pteropus vampyrus	98.45	0.00e+00	1147.00
IUUC-Rno-105312	Rattus norvegicus	98.45	0.00e+00	1157.00
IUUC-Sha-106514	Sarcophilus harrisii	99.46	0.00e+00	769.00
IUUC-Smo-108893	Selaginella moellendorffii	38.92	2.00e-123	435.00
IUUC-Sit-110248	Setaria italica	38.30	5.00e-120	424.00
IUUC-Sly-110964	Solanum lycopersicum	40.32	7.00e-125	440.00
IUUC-Stu-112882	Solanum tuberosum	40.32	7.00e-125	440.00
IUUC-Sar-113230	Sorex araneus	71.13	0.00e+00	776.00
IUUC-Sbi-113962	Sorghum bicolor	36.59	9.00e-117	413.00
IUUC-Ssc-115987	Sus scrofa	99.31	3.00e-161	560.00
IUUC-Tgu-116471	Taeniopygia guttata	98.11	0.00e+00	1153.00
IUUC-Tru-118231	Takifugu rubripes	86.64	0.00e+00	986.00
IUUC-Tsy-119415	Tarsius syrichta	97.77	0.00e+00	1135.00
IUUC-Tni-120893	Tetraodon nigroviridis	86.82	0.00e+00	994.00
IUUC-Tca-121703	Theobroma cacao	41.16	2.00e-122	432.00
IUUC-Tae-125440	Triticum aestivum	40.61	5.00e-126	444.00
IUUC-Tur-126557	Triticum urartu	40.29	3.00e-123	434.00
IUUC-Tbe-127253	Tupaia belangeri	68.90	0.00e+00	764.00
IUUC-Ttr-129100	Tursiops truncatus	96.39	0.00e+00	1102.00
IUUC-Vpa-130613	Vicugna pacos	91.58	0.00e+00	1059.00
IUUC-Vvi-130880	Vitis vinifera	40.64	4.00e-117	414.00
IUUC-Xtr-132033	Xenopus tropicalis	95.36	0.00e+00	1153.00
IUUC-Xma-133421	Xiphophorus maculatus	86.11	0.00e+00	998.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence