iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036326

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02141706

Gene Name

RNF5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000004528.2	ENSFCAT00000004529.2	ENSFCAP00000004182.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.70e-07	31.0	32	73

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iCle  ++  +v  CgH+++  Cl++w         ++ CP+C+
   Q: 32   CNICLETARE-AVVSVCGHLYCWPCLHQW---LETRPERQECPVCK 73
           99******88.888***************...555888889****7 PP

Organism

Felis catus

Protein Sequence
(Fasta)

ATEQSMAAAE EEDGGPEGPN RERGGAGATF ECNICLETAR EAVVSVCGHL YCWPCLHQWL 60
ETRPERQECP VCKAGISREK VVPLYGRGSQ KPQDPRLKTP PRPQGQRPAP ESRGGFQSFG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAACAGAAC AGTCCATGGC GGCAGCGGAG GAGGAGGACG GGGGCCCCGA AGGGCCAAAC 60
CGCGAGCGGG GCGGGGCGGG CGCGACCTTC GAATGTAATA TATGTCTGGA GACTGCTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0044390--F:ubiquitin-like protein conjugating enzyme binding
GO:0008270--F:zinc ion binding
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0010507--P:negative regulation of autophagy
GO:0031648--P:protein destabilization
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:2000785--P:regulation of autophagosome assembly
GO:0009617--P:response to bacterium

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001155	Aegilops tauschii	54.65	6.00e-24	104.00
IUUC-Aml-001417	Ailuropoda melanoleuca	95.35	1.00e-70	258.00
IUUC-Aca-004254	Anolis carolinensis	75.86	3.00e-36	143.00
IUUC-Ame-011316	Astyanax mexicanus	70.78	3.00e-58	217.00
IUUC-Bta-013109	Bos taurus	96.45	2.00e-78	284.00
IUUC-Bdi-014313	Brachypodium distachyon	54.65	5.00e-24	103.00
IUUC-Cja-019902	Callithrix jacchus	95.74	1.00e-77	281.00
IUUC-Cfa-020079	Canis familiaris	97.16	6.00e-79	286.00
IUUC-Cpo-021320	Cavia porcellus	90.42	4.00e-85	306.00
IUUC-Csa-023595	Chlorocebus sabaeus	95.74	4.00e-78	283.00
IUUC-Dre-027716	Danio rerio	74.29	6.00e-43	166.00
IUUC-Dno-029843	Dasypus novemcinctus	85.11	7.00e-56	209.00
IUUC-Dor-030170	Dipodomys ordii	95.97	1.00e-68	251.00
IUUC-Eca-033642	Equus caballus	96.95	3.00e-91	327.00
IUUC-Eeu-034778	Erinaceus europaeus	95.73	5.00e-63	232.00
IUUC-Fso-038195	Fusarium solani	40.91	3.00e-10	59.30
IUUC-Gac-042258	Gasterosteus aculeatus	80.00	1.00e-56	212.00
IUUC-Ggo-045474	Gorilla gorilla	96.45	2.00e-78	284.00
IUUC-Hsa-046046	Homo sapiens	96.45	1.00e-78	284.00
IUUC-Hvu-047043	Hordeum vulgare	54.02	1.00e-23	102.00
IUUC-Itr-048037	Ictidomys tridecemlineatus	95.33	8.00e-83	298.00
IUUC-Lch-050367	Latimeria chalumnae	70.83	5.00e-46	176.00
IUUC-Lpe-051034	Leersia perrieri	58.14	1.00e-25	109.00
IUUC-Laf-053395	Loxodonta africana	95.74	4.00e-78	283.00
IUUC-Mcc-054833	Macaca mulatta	95.74	4.00e-78	283.00
IUUC-Meu-055984	Macropus eugenii	86.08	3.00e-36	144.00
IUUC-Mdo-062437	Monodelphis domestica	85.98	7.00e-82	295.00
IUUC-Mmu-064159	Mus musculus	94.37	8.00e-78	282.00
IUUC-Mac-065053	Musa acuminata	57.65	6.00e-24	104.00
IUUC-Mlu-067689	Myotis lucifugus	89.51	7.00e-82	295.00
IUUC-Nle-069705	Nomascus leucogenys	96.45	1.00e-78	284.00
IUUC-Opr-070392	Ochotona princeps	77.97	2.00e-20	90.90
IUUC-Ont-072482	Oreochromis niloticus	74.13	5.00e-59	220.00
IUUC-Ocu-074208	Oryctolagus cuniculus	95.74	1.00e-77	281.00
IUUC-Oba-075461	Oryza barthii	52.75	1.00e-24	106.00
IUUC-Obr-076382	Oryza brachyantha	56.98	4.00e-25	107.00
IUUC-Ogl-077553	Oryza glaberrima	56.25	1.00e-26	112.00
IUUC-Ogu-078463	Oryza glumaepatula	56.25	1.00e-26	112.00
IUUC-Oin-080177	Oryza indica	56.25	2.00e-26	112.00
IUUC-Olo-080378	Oryza longistaminata	54.65	6.00e-24	103.00
IUUC-Ome-081605	Oryza meridionalis	56.25	1.00e-26	112.00
IUUC-Oni-082458	Oryza nivara	56.25	3.00e-26	112.00
IUUC-Opu-083362	Oryza punctata	58.14	8.00e-26	110.00
IUUC-Oru-084757	Oryza rufipogon	55.00	5.00e-27	114.00
IUUC-Osa-086198	Oryza sativa	55.00	6.00e-27	114.00
IUUC-Ola-086507	Oryzias latipes	71.07	2.00e-61	228.00
IUUC-Olu-087623	Ostreococcus lucimarinus	49.25	1.00e-16	79.30
IUUC-Oga-088912	Otolemur garnettii	97.16	6.00e-79	286.00
IUUC-Oar-090284	Ovis aries	93.96	5.00e-71	259.00
IUUC-Ptr-090919	Pan troglodytes	96.83	5.00e-70	256.00
IUUC-Pan-092843	Papio anubis	95.74	4.00e-78	283.00
IUUC-Pfo-096818	Poecilia formosa	79.37	7.00e-57	213.00
IUUC-Pab-098244	Pongo abelii	95.74	5.00e-78	283.00
IUUC-Pop-099595	Populus trichocarpa	55.91	3.00e-27	114.00
IUUC-Pca-100319	Procavia capensis	95.73	4.00e-82	296.00
IUUC-Pva-102249	Pteropus vampyrus	91.49	2.00e-71	261.00
IUUC-Rno-106042	Rattus norvegicus	94.37	8.00e-78	282.00
IUUC-Smo-109079	Selaginella moellendorffii	48.19	2.00e-22	100.00
IUUC-Sit-110690	Setaria italica	53.57	2.00e-22	99.40
IUUC-Sly-110917	Solanum lycopersicum	52.94	2.00e-25	108.00
IUUC-Stu-112552	Solanum tuberosum	52.94	3.00e-25	108.00
IUUC-Sbi-114275	Sorghum bicolor	54.65	1.00e-23	102.00
IUUC-Ssc-115934	Sus scrofa	97.16	6.00e-79	286.00
IUUC-Tru-118679	Takifugu rubripes	61.73	1.00e-23	101.00
IUUC-Tsy-119615	Tarsius syrichta	94.37	3.00e-75	273.00
IUUC-Tca-121830	Theobroma cacao	45.26	4.00e-26	111.00
IUUC-Tae-124655	Triticum aestivum	46.36	5.00e-24	103.00
IUUC-Tur-126198	Triticum urartu	54.65	8.00e-24	103.00
IUUC-Tbe-127773	Tupaia belangeri	94.33	5.00e-75	273.00
IUUC-Ttr-128690	Tursiops truncatus	94.87	1.00e-62	231.00
IUUC-Vvi-131225	Vitis vinifera	60.00	3.00e-26	110.00
IUUC-Xtr-132608	Xenopus tropicalis	81.67	8.00e-47	179.00
IUUC-Xma-134225	Xiphophorus maculatus	79.37	3.00e-57	214.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence