iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054141

UUCD1 version

UUC-LoA-00709

Ensembl Protein ID

ENSLAFP00000018546.1

UniProt Accession

G3TSI8; G3TSI8_LOXAF

Protein Name

Uncharacterized protein

Gene Name

CISH

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000022193.2	ENSLAFT00000030348.1	ENSLAFP00000018546.1
ENSLAFG00000022193.2	ENSLAFT00000022371.2	ENSLAFP00000017619.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.10e-15	56.2	210	257

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 1    lsklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           l++++++rs+ rSLqhLCRl+I+r + +     +d+LPLP+++ dYL+++++q
   Q: 210  LVQPFVRRSSARSLQHLCRLVINRVVAD-----VDCLPLPRRMADYLRQYPFQ 257
           57999***********************.....8****************986 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MVLCVQGPCS LLAEEQIGQQ TLKARSLELP ESAMQPLPVG VFLEEVAEEI PAQLESEQPK 60
VLDPEEDLLC IAKTFSYLRE SGWYWGSITA SEARQHLQKM PEGTFLVRDS THPSYLFTLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCCTCT GCGTTCAGGG TTAAATGCCA TTCTTTGCCC CCACCCAGCC CCTGCGCCGG 60
ACGTCCCGGA GAGCACGGGC CTCGTGCTCA CTGCTGGGCG TTGGGAGGGC TTATTGGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028425--CIS
IPR000980--SH2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0005886--C:plasma membrane
GO:0035556--P:intracellular signal transduction
GO:0007205--P:protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001189	Ailuropoda melanoleuca	90.12	6.00e-119	419.00
IUUC-Aca-004372	Anolis carolinensis	62.31	3.00e-87	314.00
IUUC-Ame-010787	Astyanax mexicanus	47.29	2.00e-53	202.00
IUUC-Bta-012826	Bos taurus	86.43	2.00e-120	424.00
IUUC-Cja-020004	Callithrix jacchus	86.51	2.00e-106	378.00
IUUC-Cfa-020150	Canis familiaris	87.25	3.00e-109	387.00
IUUC-Csa-023173	Chlorocebus sabaeus	86.51	5.00e-108	383.00
IUUC-Dre-028606	Danio rerio	44.07	2.00e-34	138.00
IUUC-Dno-028956	Dasypus novemcinctus	88.28	3.00e-124	437.00
IUUC-Dor-030148	Dipodomys ordii	70.93	3.00e-95	340.00
IUUC-Ete-032313	Echinops telfairi	87.11	3.00e-110	390.00
IUUC-Eca-033422	Equus caballus	90.70	6.00e-129	452.00
IUUC-Eeu-034806	Erinaceus europaeus	89.24	1.00e-109	389.00
IUUC-Fca-036374	Felis catus	90.70	2.00e-122	431.00
IUUC-Fal-036801	Ficedula albicollis	67.18	2.00e-90	325.00
IUUC-Gmo-038483	Gadus morhua	41.06	1.00e-33	136.00
IUUC-Gga-040891	Gallus gallus	67.18	1.00e-84	306.00
IUUC-Gac-042147	Gasterosteus aculeatus	40.38	5.00e-34	137.00
IUUC-Ggo-045511	Gorilla gorilla	86.90	1.00e-108	385.00
IUUC-Hsa-046678	Homo sapiens	86.87	4.00e-112	396.00
IUUC-Itr-048397	Ictidomys tridecemlineatus	90.31	2.00e-127	447.00
IUUC-Lch-050555	Latimeria chalumnae	55.68	7.00e-72	263.00
IUUC-Mcc-055401	Macaca mulatta	86.11	1.00e-106	379.00
IUUC-Meu-056592	Macropus eugenii	68.53	2.00e-89	321.00
IUUC-Mga-059515	Meleagris gallopavo	66.15	2.00e-80	291.00
IUUC-Mmr-060848	Microcebus murinus	89.64	3.00e-114	404.00
IUUC-Mdo-062720	Monodelphis domestica	67.05	6.00e-91	326.00
IUUC-Mmu-063348	Mus musculus	87.98	2.00e-123	434.00
IUUC-Mpu-065834	Mustela putorius furo	89.92	8.00e-121	426.00
IUUC-Mlu-067687	Myotis lucifugus	84.50	5.00e-101	360.00
IUUC-Nle-069277	Nomascus leucogenys	87.26	3.00e-111	394.00
IUUC-Ont-071890	Oreochromis niloticus	44.50	4.00e-36	144.00
IUUC-Oan-073672	Ornithorhynchus anatinus	65.64	9.00e-91	325.00
IUUC-Ocu-073875	Oryctolagus cuniculus	88.84	5.00e-119	420.00
IUUC-Ola-087140	Oryzias latipes	43.71	5.00e-24	103.00
IUUC-Oga-087943	Otolemur garnettii	89.15	1.00e-121	428.00
IUUC-Oar-090194	Ovis aries	85.38	2.00e-116	410.00
IUUC-Ptr-090934	Pan troglodytes	86.11	1.00e-106	378.00
IUUC-Pan-092121	Papio anubis	86.49	3.00e-111	394.00
IUUC-Psi-093733	Pelodiscus sinensis	63.49	3.00e-86	310.00
IUUC-Pfo-096313	Poecilia formosa	47.76	9.00e-44	169.00
IUUC-Pab-098439	Pongo abelii	86.87	2.00e-111	394.00
IUUC-Pca-101010	Procavia capensis	93.80	8.00e-134	469.00
IUUC-Pva-103112	Pteropus vampyrus	88.37	2.00e-117	414.00
IUUC-Rno-105917	Rattus norvegicus	87.60	3.00e-116	410.00
IUUC-Sha-106954	Sarcophilus harrisii	67.43	7.00e-91	326.00
IUUC-Smo-109292	Selaginella moellendorffii	31.15	9.90e-02	31.60
IUUC-Sar-113001	Sorex araneus	89.24	5.00e-115	406.00
IUUC-Ssc-115922	Sus scrofa	89.44	5.00e-63	232.00
IUUC-Tgu-117338	Taeniopygia guttata	66.27	2.00e-86	311.00
IUUC-Tru-118511	Takifugu rubripes	43.75	1.00e-32	132.00
IUUC-Tsy-119434	Tarsius syrichta	88.05	3.00e-112	397.00
IUUC-Ttr-128340	Tursiops truncatus	74.81	8.00e-81	292.00
IUUC-Vpa-130443	Vicugna pacos	88.37	2.00e-123	434.00
IUUC-Xtr-131784	Xenopus tropicalis	53.48	2.00e-69	255.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence