iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021993

Ensembl Protein ID

ENSCPOP00000013901.2

UniProt Accession

H0VTB3; H0VTB3_CAVPO

Genbank Protein ID

ENSCPOP00000013901

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02054808

Gene Name

MAP3K10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000015417.3	ENSCPOT00000015568.2	ENSCPOP00000013901.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.30e-14	53.9	3	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 8    vlydyeaqnddeLtlkkGdvvlvieke...eqdegWlkgvkelegkrGlfPenFve 60
           + +dyea+ d+eLtl++Gd v+v++++   + degW+ g+   +g+ G+fP+n+v+
   Q: 3    AVFDYEAVGDEELTLRRGDRVQVLSQDcavSGDEGWWTGQ-LPSGRVGVFPSNYVA 57
           79**********************77622257*******7.99***********97 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

WTAVFDYEAV GDEELTLRRG DRVQVLSQDC AVSGDEGWWT GQLPSGRVGV FPSNYVAPST 60
PAAPAGLRLP QEIPFHELQL EEIIGVGGFG KVYRALWRGE EVAVKAARLD PEKDPAVTAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGACCGCAG TGTTCGACTA TGAGGCGGTC GGCGACGAGG AGCTGACACT GCGGAGGGGC 60
GACCGTGTCC AGGTGCTTTC CCAAGACTGC GCGGTGTCCG GCGATGAGGG CTGGTGGACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR015785--MAP3K10
IPR016231--MLK1/MLK2/MLK4
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0003714--F:transcription corepressor activity
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043507--P:positive regulation of JUN kinase activity
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001187	Ailuropoda melanoleuca	93.03	0.00e+00	949.00
IUUC-Atr-002478	Amborella trichopoda	33.33	3.00e-24	107.00
IUUC-Aca-004768	Anolis carolinensis	78.41	0.00e+00	810.00
IUUC-Aly-006459	Arabidopsis lyrata	33.45	3.00e-29	124.00
IUUC-Ath-006581	Arabidopsis thaliana	33.10	1.00e-28	122.00
IUUC-Bta-013545	Bos taurus	98.04	0.00e+00	834.00
IUUC-Bdi-014449	Brachypodium distachyon	32.36	8.00e-26	112.00
IUUC-Bol-016287	Brassica oleracea	32.62	3.00e-28	120.00
IUUC-Bra-016997	Brassica rapa	33.69	3.00e-28	120.00
IUUC-Cja-019696	Callithrix jacchus	93.85	0.00e+00	935.00
IUUC-Cfa-020789	Canis familiaris	75.21	0.00e+00	759.00
IUUC-Cre-022669	Chlamydomonas reinhardtii	33.64	3.00e-20	92.40
IUUC-Csa-024243	Chlorocebus sabaeus	93.85	0.00e+00	936.00
IUUC-Cho-024961	Choloepus hoffmanni	92.75	8.00e-112	397.00
IUUC-Dno-029095	Dasypus novemcinctus	90.22	0.00e+00	914.00
IUUC-Dme-032210	Drosophila melanogaster	50.43	2.00e-141	496.00
IUUC-Fca-036250	Felis catus	92.39	0.00e+00	954.00
IUUC-Gmo-038497	Gadus morhua	73.80	0.00e+00	794.00
IUUC-Gac-042509	Gasterosteus aculeatus	72.47	0.00e+00	764.00
IUUC-Gma-043336	Glycine max	29.62	2.00e-26	114.00
IUUC-Ggo-045471	Gorilla gorilla	89.22	0.00e+00	869.00
IUUC-Hsa-046936	Homo sapiens	94.19	0.00e+00	912.00
IUUC-Hvu-047798	Hordeum vulgare	32.27	2.00e-24	107.00
IUUC-Itr-048231	Ictidomys tridecemlineatus	95.93	0.00e+00	964.00
IUUC-Loc-052286	Lepisosteus oculatus	69.24	0.00e+00	764.00
IUUC-Mcc-055733	Macaca mulatta	90.97	0.00e+00	931.00
IUUC-Mtr-058733	Medicago truncatula	32.00	9.00e-27	115.00
IUUC-Mdo-062516	Monodelphis domestica	84.53	0.00e+00	901.00
IUUC-Mmu-064082	Mus musculus	94.62	0.00e+00	975.00
IUUC-Mac-065156	Musa acuminata	31.93	7.00e-28	119.00
IUUC-Mpu-065934	Mustela putorius furo	94.68	0.00e+00	957.00
IUUC-Mlu-068137	Myotis lucifugus	85.87	0.00e+00	920.00
IUUC-Opr-070869	Ochotona princeps	75.33	0.00e+00	776.00
IUUC-Ont-072492	Oreochromis niloticus	73.85	0.00e+00	801.00
IUUC-Ocu-074350	Oryctolagus cuniculus	91.28	0.00e+00	936.00
IUUC-Oba-075616	Oryza barthii	34.88	5.00e-25	109.00
IUUC-Obr-076215	Oryza brachyantha	34.10	4.00e-26	113.00
IUUC-Ogl-077159	Oryza glaberrima	34.88	6.00e-25	109.00
IUUC-Ogu-078228	Oryza glumaepatula	35.35	2.00e-25	111.00
IUUC-Oin-079079	Oryza indica	34.93	1.00e-25	111.00
IUUC-Olo-080309	Oryza longistaminata	35.07	2.00e-24	107.00
IUUC-Oni-082428	Oryza nivara	34.88	6.00e-25	109.00
IUUC-Opu-083527	Oryza punctata	35.35	4.00e-25	110.00
IUUC-Oru-084678	Oryza rufipogon	34.93	1.00e-25	111.00
IUUC-Osa-086117	Oryza sativa	34.93	1.00e-25	111.00
IUUC-Oga-088351	Otolemur garnettii	93.85	0.00e+00	1011.00
IUUC-Ptr-091607	Pan troglodytes	94.19	0.00e+00	913.00
IUUC-Pan-092403	Papio anubis	93.70	0.00e+00	908.00
IUUC-Pab-098396	Pongo abelii	94.19	0.00e+00	914.00
IUUC-Pop-099554	Populus trichocarpa	29.17	3.00e-24	107.00
IUUC-Ppe-101208	Prunus persica	32.17	5.00e-26	113.00
IUUC-Rno-105688	Rattus norvegicus	94.79	0.00e+00	976.00
IUUC-Smo-109661	Selaginella moellendorffii	32.72	9.00e-26	110.00
IUUC-Sit-110427	Setaria italica	34.58	4.00e-25	110.00
IUUC-Sly-111849	Solanum lycopersicum	35.09	8.00e-26	112.00
IUUC-Stu-112224	Solanum tuberosum	35.09	1.00e-25	111.00
IUUC-Sbi-113963	Sorghum bicolor	35.85	9.00e-26	112.00
IUUC-Ssc-115332	Sus scrofa	94.95	0.00e+00	986.00
IUUC-Tru-117692	Takifugu rubripes	69.76	0.00e+00	791.00
IUUC-Tsy-119412	Tarsius syrichta	92.13	5.00e-65	242.00
IUUC-Tca-121565	Theobroma cacao	36.15	2.00e-26	114.00
IUUC-Tae-125555	Triticum aestivum	32.10	7.00e-25	108.00
IUUC-Tur-126322	Triticum urartu	32.26	3.00e-25	110.00
IUUC-Tbe-127643	Tupaia belangeri	97.31	0.00e+00	645.00
IUUC-Ttr-128550	Tursiops truncatus	92.87	0.00e+00	1003.00
IUUC-Vvi-131372	Vitis vinifera	32.62	6.00e-24	105.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence