iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132322

Ensembl Protein ID

ENSXETP00000041569.4

UniProt Accession

Q640S9; Q640S9_XENTR

Genbank Protein ID

AAH82510.1

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AAMC01085935

Gene Name

yes1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000019176.4	ENSXETT00000041569.4	ENSXETP00000041569.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.20e-14	52.8	90	145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++++L+++kG+  ++i  ++++++W+++ + ++gk G +P+n+v+ ++
   Q: 90   FVALYDYEARTTEDLSFRKGERFQII--NNTEGDWWEARSIATGKTGYIPSNYVAPAD 145
           789***********************..8999**********************9875 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MGCIKSKEDK GPSIKYRTEP KPDSGSQYGG DPTQATQSPG IKGPAPNFNS HSMTPFGGSS 60
GITPFGGASS IFSPTPVPYP GGLTGGVTVF VALYDYEART TEDLSFRKGE RFQIINNTEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTCTCCTT AGCGCCTCTC TGCCATCATA GGGACACGGG AGAGAAAGTC TGCGCTGCCG 60
GCTGCTTATC GTTCATTTCA GGAGGAAAAG GAACTTACAT GAGTCTCCTG GAGTATAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0034334--P:adherens junction maintenance
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0060027--P:convergent extension involved in gastrulation
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0045859--P:regulation of protein kinase activity
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

xtr:493548

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002374	Ailuropoda melanoleuca	90.41	0.00e+00	993.00
IUUC-Apl-004032	Anas platyrhynchos	93.16	0.00e+00	1037.00
IUUC-Aca-004255	Anolis carolinensis	90.74	0.00e+00	1031.00
IUUC-Ath-007146	Arabidopsis thaliana	34.20	2.00e-22	101.00
IUUC-Ame-010954	Astyanax mexicanus	88.12	0.00e+00	999.00
IUUC-Bta-013503	Bos taurus	89.65	0.00e+00	967.00
IUUC-Bol-016049	Brassica oleracea	33.53	3.00e-17	84.00
IUUC-Bra-017486	Brassica rapa	32.84	3.00e-21	97.10
IUUC-Cel-018682	Caenorhabditis elegans	57.72	3.00e-149	521.00
IUUC-Cja-019694	Callithrix jacchus	90.06	0.00e+00	978.00
IUUC-Cfa-020402	Canis familiaris	90.39	0.00e+00	993.00
IUUC-Cpo-022506	Cavia porcellus	90.39	0.00e+00	992.00
IUUC-Csa-023713	Chlorocebus sabaeus	90.42	0.00e+00	981.00
IUUC-Cin-025390	Ciona intestinalis	71.58	0.00e+00	660.00
IUUC-Csv-026029	Ciona savignyi	64.55	0.00e+00	642.00
IUUC-Dre-027978	Danio rerio	87.18	0.00e+00	966.00
IUUC-Dno-029897	Dasypus novemcinctus	88.66	0.00e+00	876.00
IUUC-Dor-030202	Dipodomys ordii	94.47	0.00e+00	904.00
IUUC-Eca-034157	Equus caballus	89.46	0.00e+00	984.00
IUUC-Eeu-034950	Erinaceus europaeus	83.80	1.00e-165	575.00
IUUC-Fca-036233	Felis catus	90.39	0.00e+00	1025.00
IUUC-Fal-037461	Ficedula albicollis	92.79	0.00e+00	1045.00
IUUC-Gmo-038929	Gadus morhua	80.87	0.00e+00	911.00
IUUC-Gga-041107	Gallus gallus	92.79	0.00e+00	1035.00
IUUC-Gac-042321	Gasterosteus aculeatus	84.49	0.00e+00	941.00
IUUC-Hsa-047010	Homo sapiens	90.06	0.00e+00	990.00
IUUC-Lch-050239	Latimeria chalumnae	90.39	0.00e+00	1018.00
IUUC-Loc-052314	Lepisosteus oculatus	89.54	0.00e+00	959.00
IUUC-Laf-053517	Loxodonta africana	89.83	0.00e+00	966.00
IUUC-Mcc-055626	Macaca mulatta	90.42	0.00e+00	982.00
IUUC-Mga-059310	Meleagris gallopavo	92.79	0.00e+00	1035.00
IUUC-Mmr-061652	Microcebus murinus	89.65	0.00e+00	985.00
IUUC-Mdo-062963	Monodelphis domestica	88.91	0.00e+00	994.00
IUUC-Mmu-064128	Mus musculus	89.46	0.00e+00	1002.00
IUUC-Mpu-065906	Mustela putorius furo	90.39	0.00e+00	995.00
IUUC-Mlu-067035	Myotis lucifugus	90.44	0.00e+00	991.00
IUUC-Nle-069041	Nomascus leucogenys	86.00	0.00e+00	931.00
IUUC-Opr-070299	Ochotona princeps	81.15	0.00e+00	867.00
IUUC-Ont-072337	Oreochromis niloticus	83.99	0.00e+00	958.00
IUUC-Oan-072997	Ornithorhynchus anatinus	97.14	0.00e+00	930.00
IUUC-Ocu-074171	Oryctolagus cuniculus	90.57	0.00e+00	999.00
IUUC-Ola-086619	Oryzias latipes	83.85	0.00e+00	958.00
IUUC-Oga-087957	Otolemur garnettii	89.65	0.00e+00	978.00
IUUC-Oar-089670	Ovis aries	88.54	0.00e+00	977.00
IUUC-Ptr-091352	Pan troglodytes	90.06	0.00e+00	991.00
IUUC-Pan-092202	Papio anubis	90.42	0.00e+00	982.00
IUUC-Psi-093310	Pelodiscus sinensis	92.61	0.00e+00	1046.00
IUUC-Pma-094232	Petromyzon marinus	86.75	0.00e+00	859.00
IUUC-Pfo-096137	Poecilia formosa	81.04	0.00e+00	937.00
IUUC-Pab-098301	Pongo abelii	94.85	0.00e+00	940.00
IUUC-Pva-102592	Pteropus vampyrus	86.32	0.00e+00	934.00
IUUC-Rno-105544	Rattus norvegicus	89.65	0.00e+00	977.00
IUUC-Stu-112831	Solanum tuberosum	33.17	1.00e-21	98.60
IUUC-Sar-113364	Sorex araneus	87.25	0.00e+00	924.00
IUUC-Tgu-117380	Taeniopygia guttata	92.79	0.00e+00	1045.00
IUUC-Tru-117594	Takifugu rubripes	84.78	0.00e+00	956.00
IUUC-Tni-120433	Tetraodon nigroviridis	83.42	0.00e+00	935.00
IUUC-Ttr-128893	Tursiops truncatus	89.46	0.00e+00	984.00
IUUC-Vpa-130060	Vicugna pacos	90.20	0.00e+00	982.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence