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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046539
Ensembl Protein ID ENSP00000462337.1
UniProt Accession Q14119; VEZF1_HUMAN
Genbank Protein ID BAA05663.1; ENSP00000462337
Protein Name Vascular endothelial zinc finger 1; Putative transcription factor DB1; Zinc finger protein 161
Genbank Nucleotide ID D28118; AC015813
Gene Name VEZF1; DB1; ZNF161
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000136451.8 ENST00000258963.7 ENSP00000258963.3
ENSG00000136451.8 ENST00000584396.5 ENSP00000464687.1
ENSG00000136451.8 ENST00000581208.1 ENSP00000462337.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
miRTarBasemicroRNATRANSFACRepTar
SomamiRmiRcodeRAID2LncRNADisease
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
OMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDUniProtPHOSIDABioGRID
mUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/ZnF/UBZ 1.80e-07 32.9 176 192
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/ZnF/UBZ
   S: 4    CPvCqkm.vdqtdfeeH 19
           C++C+k+  d++++++H
   Q: 176  CEMCGKAfRDVYHLNRH 192
           ***************** PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     Possible transcription factor. Specifically binds to the CT/GC-rich region of the interleukin-3 promoter and mediates tax transactivation of IL-3.
 Possible transcription factor. Specifically binds to the CT/GC-rich region of the interleukin-3 promoter and mediates tax transactivation of IL-3.
Protein Sequence
(Fasta)
MEANWTAFLF QAHEASHHQQ QAAQNSLLPL LSSAVEPPDQ KPLLPIPITQ KPQGAPETLK 60
DAIGIKKEKP KTSFVCTYCS KAFRDSYHLR RHESCHTGIK LVSRPKKTPT TVVPLISTIA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046539|UBD,UBZ|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGGAAGTGGC CGCGCTCGGC GCTGCCATGT TGAGGAGCCG CCGCTGCCGT TGCCGCCGCC 60
GCCGCCGCCG CTTTGTTGTC GCCTCCTCCG GCTGAGGAGG CTCCCCGAGC GGGGGGAGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046539|UBD,UBZ|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0010--Activator
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR023413--GFP-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR013087--Znf_C2H2_type
IPR001781--Znf_LIM
PROSITE

PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
SMART

SM00355--ZnF_C2H2
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0001525--P:angiogenesis
GO:0006968--P:cellular defense response
GO:0001885--P:endothelial cell development
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006366--P:transcription from RNA polymerase II promoter
KEGG hsa:7716
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002029 Ailuropoda melanoleuca 95.55 0.00e+00 753.00
IUUC-Apl-003373 Anas platyrhynchos 89.31 0.00e+00 725.00
IUUC-Aca-005340 Anolis carolinensis 94.06 4.00e-153 533.00
IUUC-Ame-011155 Astyanax mexicanus 56.41 5.00e-151 527.00
IUUC-Bta-012345 Bos taurus 98.39 0.00e+00 770.00
IUUC-Cja-019080 Callithrix jacchus 94.36 0.00e+00 756.00
IUUC-Cfa-021007 Canis familiaris 95.63 0.00e+00 779.00
IUUC-Cpo-021494 Cavia porcellus 94.24 0.00e+00 768.00
IUUC-Csa-023995 Chlorocebus sabaeus 99.23 0.00e+00 791.00
IUUC-Cho-024441 Choloepus hoffmanni 97.79 0.00e+00 765.00
IUUC-Dre-027737 Danio rerio 53.58 4.00e-138 484.00
IUUC-Dno-029621 Dasypus novemcinctus 97.89 0.00e+00 785.00
IUUC-Eca-033916 Equus caballus 98.24 0.00e+00 792.00
IUUC-Eeu-035069 Erinaceus europaeus 95.50 2.00e-180 625.00
IUUC-Fca-036019 Felis catus 95.01 0.00e+00 770.00
IUUC-Fal-036792 Ficedula albicollis 89.25 0.00e+00 745.00
IUUC-Gmo-038865 Gadus morhua 48.78 8.00e-120 423.00
IUUC-Gga-040650 Gallus gallus 90.09 0.00e+00 752.00
IUUC-Gac-041688 Gasterosteus aculeatus 56.09 7.00e-147 514.00
IUUC-Ggo-044834 Gorilla gorilla 99.23 0.00e+00 764.00
IUUC-Itr-048584 Ictidomys tridecemlineatus 98.59 0.00e+00 766.00
IUUC-Lch-050011 Latimeria chalumnae 67.76 9.00e-172 596.00
IUUC-Loc-052051 Lepisosteus oculatus 55.43 1.00e-147 516.00
IUUC-Laf-053768 Loxodonta africana 94.37 0.00e+00 782.00
IUUC-Mcc-055529 Macaca mulatta 99.20 0.00e+00 771.00
IUUC-Meu-055911 Macropus eugenii 90.29 5.00e-172 597.00
IUUC-Mga-060192 Meleagris gallopavo 90.00 0.00e+00 754.00
IUUC-Mmr-060984 Microcebus murinus 96.74 0.00e+00 767.00
IUUC-Mdo-062265 Monodelphis domestica 92.91 0.00e+00 795.00
IUUC-Mmu-063475 Mus musculus 97.89 0.00e+00 792.00
IUUC-Mpu-066117 Mustela putorius furo 96.16 0.00e+00 748.00
IUUC-Mlu-067275 Myotis lucifugus 95.39 0.00e+00 793.00
IUUC-Nle-069246 Nomascus leucogenys 98.59 0.00e+00 758.00
IUUC-Opr-070726 Ochotona princeps 97.59 0.00e+00 763.00
IUUC-Ont-072277 Oreochromis niloticus 59.46 8.00e-151 526.00
IUUC-Oan-072979 Ornithorhynchus anatinus 91.88 0.00e+00 769.00
IUUC-Ocu-073937 Oryctolagus cuniculus 98.19 0.00e+00 764.00
IUUC-Ola-087493 Oryzias latipes 68.10 2.00e-116 412.00
IUUC-Oga-088803 Otolemur garnettii 98.08 0.00e+00 780.00
IUUC-Oar-089981 Ovis aries 98.39 0.00e+00 768.00
IUUC-Ptr-091099 Pan troglodytes 99.40 0.00e+00 745.00
IUUC-Pan-092907 Papio anubis 99.04 0.00e+00 791.00
IUUC-Psi-093337 Pelodiscus sinensis 90.06 0.00e+00 733.00
IUUC-Pfo-096575 Poecilia formosa 53.01 5.00e-142 498.00
IUUC-Pva-102541 Pteropus vampyrus 97.12 0.00e+00 815.00
IUUC-Rno-105906 Rattus norvegicus 98.46 0.00e+00 776.00
IUUC-Sha-106911 Sarcophilus harrisii 95.17 0.00e+00 758.00
IUUC-Ssl-108572 Sclerotinia sclerotiorum 37.25 1.70e-01 30.00
IUUC-Sar-113280 Sorex araneus 91.75 0.00e+00 695.00
IUUC-Ssc-116365 Sus scrofa 98.66 0.00e+00 787.00
IUUC-Tgu-116650 Taeniopygia guttata 93.39 0.00e+00 724.00
IUUC-Tru-117810 Takifugu rubripes 56.72 8.00e-149 520.00
IUUC-Tsy-119364 Tarsius syrichta 94.58 0.00e+00 714.00
IUUC-Tni-120633 Tetraodon nigroviridis 56.83 2.00e-149 522.00
IUUC-Tbe-127293 Tupaia belangeri 98.59 0.00e+00 761.00
IUUC-Ttr-128189 Tursiops truncatus 93.16 0.00e+00 724.00
IUUC-Xtr-131813 Xenopus tropicalis 76.04 0.00e+00 674.00
Created Date 25-Jun-2017

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