iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105295

Ensembl Protein ID

ENSRNOP00000069980.1

UniProt Accession

A0A0G2JWR2; A0A0G2JWR2_RAT

Genbank Protein ID

ENSRNOP00000069980

Protein Name

Protein kinase C and casein kinase substrate in neurons protein 1

Genbank Nucleotide ID

AC095263

Gene Name

Pacsin1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000054603.1	ENSRNOT00000090820.1	ENSRNOP00000069980.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.40e-15	55.8	386	441

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v++lydy++q++deL++k+Gd ++ +  ee ++gW++g + ++g+ Gl P+n+ve +
   Q: 386  RVRALYDYDGQEQDELSFKAGDELTKL-GEEDEQGWCRG-RLDSGQLGLYPANYVEAI 441
           699************************.***********.59*************975 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSGPYDEASE EITDSFWEVG NYKRTVKRID DGHRLCNDLM SCVQERAKIE KAYAQQLTDW 60
AKRWRQLIEK VPQYGSLERA WGAMMTEADK VSELHQEVKN SLLNEDLEKV KNWQKDAYHK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGGCC CCTACGATGA GGCCTCGGAG GAGATCACAG ATAGCTTCTG GGAGGTGAGT 60
GGAGGTCTCA GCTCCCTTGA CCTCAGCCTT GTACCCAGAC TCCCTTGCGC CCCTTCAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028518--PACSIN1
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0030137--C:COPI-coated vesicle
GO:0043209--C:myelin sheath
GO:0032587--C:ruffle membrane
GO:0045202--C:synapse
GO:0005543--F:phospholipid binding
GO:0007015--P:actin filament organization
GO:0045806--P:negative regulation of endocytosis
GO:0048666--P:neuron development
GO:0097320--P:plasma membrane tubulation
GO:0072657--P:protein localization to membrane
GO:0048488--P:synaptic vesicle endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001861	Ailuropoda melanoleuca	83.40	0.00e+00	751.00
IUUC-Apl-003667	Anas platyrhynchos	80.75	0.00e+00	657.00
IUUC-Aca-005229	Anolis carolinensis	79.37	0.00e+00	689.00
IUUC-Ame-011410	Astyanax mexicanus	71.01	5.00e-174	603.00
IUUC-Bta-013509	Bos taurus	91.22	0.00e+00	736.00
IUUC-Cja-019659	Callithrix jacchus	92.79	0.00e+00	803.00
IUUC-Cfa-020396	Canis familiaris	92.34	0.00e+00	776.00
IUUC-Cpo-022376	Cavia porcellus	93.47	0.00e+00	779.00
IUUC-Csa-023701	Chlorocebus sabaeus	92.57	0.00e+00	774.00
IUUC-Dre-027456	Danio rerio	72.20	0.00e+00	643.00
IUUC-Eca-033679	Equus caballus	85.68	0.00e+00	706.00
IUUC-Fca-036314	Felis catus	92.12	0.00e+00	775.00
IUUC-Fal-037300	Ficedula albicollis	80.49	0.00e+00	692.00
IUUC-Gmo-038571	Gadus morhua	65.71	7.00e-156	543.00
IUUC-Gga-040626	Gallus gallus	79.60	0.00e+00	649.00
IUUC-Gac-041445	Gasterosteus aculeatus	67.34	1.00e-161	562.00
IUUC-Ggo-045557	Gorilla gorilla	92.79	0.00e+00	776.00
IUUC-Hsa-045778	Homo sapiens	92.79	0.00e+00	776.00
IUUC-Itr-048856	Ictidomys tridecemlineatus	93.47	0.00e+00	781.00
IUUC-Lch-050070	Latimeria chalumnae	69.80	0.00e+00	658.00
IUUC-Loc-051764	Lepisosteus oculatus	75.78	0.00e+00	665.00
IUUC-Laf-054465	Loxodonta africana	92.36	0.00e+00	796.00
IUUC-Mcc-055324	Macaca mulatta	92.34	0.00e+00	775.00
IUUC-Meu-056348	Macropus eugenii	87.16	0.00e+00	733.00
IUUC-Mga-059285	Meleagris gallopavo	81.22	0.00e+00	640.00
IUUC-Mmr-061367	Microcebus murinus	93.24	0.00e+00	738.00
IUUC-Mdo-062432	Monodelphis domestica	57.87	3.00e-135	474.00
IUUC-Mmu-064347	Mus musculus	95.46	0.00e+00	819.00
IUUC-Mpu-066864	Mustela putorius furo	91.89	0.00e+00	773.00
IUUC-Nle-070027	Nomascus leucogenys	93.16	0.00e+00	744.00
IUUC-Ont-072188	Oreochromis niloticus	70.18	4.00e-178	617.00
IUUC-Ocu-074297	Oryctolagus cuniculus	93.69	0.00e+00	749.00
IUUC-Ola-087188	Oryzias latipes	70.34	1.00e-160	558.00
IUUC-Oga-088856	Otolemur garnettii	92.79	0.00e+00	754.00
IUUC-Oar-090278	Ovis aries	83.78	0.00e+00	634.00
IUUC-Pan-092056	Papio anubis	92.57	0.00e+00	774.00
IUUC-Pfo-097528	Poecilia formosa	66.82	2.00e-149	522.00
IUUC-Pab-098202	Pongo abelii	92.34	0.00e+00	773.00
IUUC-Pca-100881	Procavia capensis	91.44	0.00e+00	765.00
IUUC-Pva-102181	Pteropus vampyrus	91.44	0.00e+00	768.00
IUUC-Sha-107163	Sarcophilus harrisii	76.36	0.00e+00	645.00
IUUC-Ssc-115685	Sus scrofa	90.99	0.00e+00	767.00
IUUC-Tgu-116524	Taeniopygia guttata	73.99	1.00e-175	609.00
IUUC-Tru-118248	Takifugu rubripes	65.32	3.00e-147	514.00
IUUC-Tni-120717	Tetraodon nigroviridis	67.94	1.00e-150	525.00
IUUC-Ttr-129069	Tursiops truncatus	92.43	0.00e+00	742.00
IUUC-Xtr-132759	Xenopus tropicalis	70.70	3.00e-179	620.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence