iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105777

Ensembl Protein ID

ENSRNOP00000009544.6

UniProt Accession

B2RZ98; D3ZS40; B2RZ98_RAT

Genbank Protein ID

AAI67076.1; EDM15882.1

Protein Name

Ncf4 protein; Neutrophil cytosolic factor 4; Similar to neutrophil cytosolic factor 4, isoform CRA_a

Genbank Nucleotide ID

AABR07058489; CH473950

Gene Name

Ncf4; LOC500904; rCG_60084

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000006940.6	ENSRNOT00000009544.6	ENSRNOP00000009544.6

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.00e-12	45.2	175	228
ULD/UDP/UFD/PB1	3.90e-20	72.2	237	329

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            ++l+d++++++ eL++k+Gdv++++   + +++Wl+g  +++g  G+fP  Fv+ l+
   Q: 175  AEALFDFTGNSKLELSFKAGDVIFLL--SKINKDWLEG--TTQGATGIFPGSFVKILK 228
           689***********************..8999******..8*************9876 PP

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirs......faldlekpgkfedLlkavrtltelknsevalkYeDedGDlvtlksDedldkavslla...skksll..r 78
           t+++++++++++        +++dl+++++f+dLl+++r+  e++++++al+Y+D++GDlv+l sDed+  +v++++   s+k+l+  +
   Q: 237  TNWLRCYFYEDTGKtikdiaVEEDLSSTPLFKDLLALMRR--EFQREDIALNYQDAEGDLVRLLSDEDVGLMVKQAQglpSQKRLFpwK 323
           589*********9999************************..********************************************999 PP
   S: 79   lliqkk 84
           l++++k
   Q: 324  LHVTQK 329
           *99985 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MALAQQLRSE SDFEQLPDDV AISANIADIE EKRGFTSHFV FVIEVKTKGG SKYLIYRRYR 60
QFYALQSKLE ERFGPESKNS PFTCSLPTLP AKVYMGVKQE IAETRIPALN AYMKNLLSLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAAGTGGG TGAGAAGAAG TGTGGAGCCA GGCAGCTCAG AGTCTCAAGG AGGTACTTCA 60
AGGAGGGTCC AGAGAAGCTG GGGAGGGAGG GACCTCCTCA AAGGGTGCTC CCGAGGACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000919--NCF_P40
IPR000270--PB1_dom
IPR001683--Phox
IPR001452--SH3_domain

PROSITE

PS51745--PB1
PS50195--PX
PS50002--SH3

Pfam

PF00564--PB1
PF00787--PX
PF00018--SH3_1

PRINTS

PR00497--P40PHOX
PR00452--SH3DOMAIN

SMART

SM00666--PB1
SM00312--PX
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0010008--C:endosome membrane
GO:0043020--C:NADPH oxidase complex
GO:0005802--C:trans-Golgi network
GO:0005086--F:ARF guanyl-nucleotide exchange factor activity
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0016176--F:superoxide-generating NADPH oxidase activator activity
GO:0016192--P:vesicle-mediated transport

KEGG

rno:500904

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001675	Ailuropoda melanoleuca	85.84	1.00e-174	605.00
IUUC-Apl-003431	Anas platyrhynchos	66.08	7.00e-135	473.00
IUUC-Aca-005176	Anolis carolinensis	70.24	9.00e-136	476.00
IUUC-Ame-011492	Astyanax mexicanus	58.31	4.00e-116	410.00
IUUC-Bta-013434	Bos taurus	87.02	7.00e-162	562.00
IUUC-Cja-019788	Callithrix jacchus	86.73	4.00e-176	610.00
IUUC-Cfa-021039	Canis familiaris	86.43	8.00e-169	585.00
IUUC-Cpo-021848	Cavia porcellus	85.84	4.00e-169	587.00
IUUC-Csa-023733	Chlorocebus sabaeus	86.05	1.00e-151	528.00
IUUC-Dre-027732	Danio rerio	53.37	9.00e-100	356.00
IUUC-Dno-029154	Dasypus novemcinctus	78.65	1.00e-153	535.00
IUUC-Eca-034062	Equus caballus	86.73	1.00e-169	588.00
IUUC-Eeu-035129	Erinaceus europaeus	73.15	6.00e-60	224.00
IUUC-Fca-036402	Felis catus	87.32	3.00e-177	613.00
IUUC-Fal-037105	Ficedula albicollis	67.55	8.00e-136	476.00
IUUC-Gmo-039144	Gadus morhua	53.12	8.00e-36	142.00
IUUC-Gga-040526	Gallus gallus	66.37	9.00e-134	469.00
IUUC-Ggo-044667	Gorilla gorilla	86.05	2.00e-131	462.00
IUUC-Hsa-045779	Homo sapiens	87.32	4.00e-178	616.00
IUUC-Itr-048385	Ictidomys tridecemlineatus	73.68	2.00e-135	474.00
IUUC-Lch-050264	Latimeria chalumnae	52.97	6.00e-113	400.00
IUUC-Loc-051887	Lepisosteus oculatus	55.65	8.00e-107	380.00
IUUC-Laf-054411	Loxodonta africana	81.02	5.00e-153	533.00
IUUC-Mcc-055835	Macaca mulatta	87.20	4.00e-172	597.00
IUUC-Meu-056875	Macropus eugenii	80.30	5.00e-94	336.00
IUUC-Mga-059737	Meleagris gallopavo	65.78	3.00e-133	468.00
IUUC-Mmr-061065	Microcebus murinus	83.68	2.00e-118	418.00
IUUC-Mdo-062598	Monodelphis domestica	80.00	2.00e-157	547.00
IUUC-Mmu-063643	Mus musculus	97.35	0.00e+00	684.00
IUUC-Mpu-066142	Mustela putorius furo	88.20	2.00e-179	620.00
IUUC-Mlu-067898	Myotis lucifugus	88.89	3.00e-45	172.00
IUUC-Nle-069935	Nomascus leucogenys	74.78	9.00e-141	492.00
IUUC-Opr-070204	Ochotona princeps	83.08	6.00e-130	456.00
IUUC-Ont-072261	Oreochromis niloticus	54.57	8.00e-106	376.00
IUUC-Oan-072846	Ornithorhynchus anatinus	80.89	4.00e-74	269.00
IUUC-Ocu-074683	Oryctolagus cuniculus	87.06	5.00e-177	613.00
IUUC-Ola-086700	Oryzias latipes	53.30	1.00e-96	346.00
IUUC-Oga-087992	Otolemur garnettii	87.09	2.00e-171	594.00
IUUC-Oar-089828	Ovis aries	86.22	2.00e-159	554.00
IUUC-Pan-092264	Papio anubis	87.32	6.00e-178	616.00
IUUC-Psi-093800	Pelodiscus sinensis	65.49	6.00e-129	453.00
IUUC-Pfo-096677	Poecilia formosa	51.69	6.00e-90	323.00
IUUC-Pab-097920	Pongo abelii	86.43	2.00e-176	611.00
IUUC-Pca-100312	Procavia capensis	69.62	5.00e-96	344.00
IUUC-Pva-102113	Pteropus vampyrus	84.94	1.00e-130	459.00
IUUC-Sha-106666	Sarcophilus harrisii	79.71	3.00e-164	570.00
IUUC-Ssc-116056	Sus scrofa	86.73	2.00e-179	620.00
IUUC-Tgu-116797	Taeniopygia guttata	68.14	3.00e-138	484.00
IUUC-Tru-117860	Takifugu rubripes	53.31	7.00e-97	347.00
IUUC-Tsy-119537	Tarsius syrichta	84.24	2.00e-80	292.00
IUUC-Tni-119946	Tetraodon nigroviridis	55.11	1.00e-98	353.00
IUUC-Tbe-127274	Tupaia belangeri	75.00	1.00e-107	382.00
IUUC-Ttr-129026	Tursiops truncatus	86.60	3.00e-107	380.00
IUUC-Xtr-131910	Xenopus tropicalis	51.92	2.00e-106	378.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence