iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028060

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BX682555

Gene Name

RNF222; rnf222

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000098547.1	ENSDART00000164561.1	ENSDARP00000138866.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.70e-10	41.5	16	65

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw......pglknssskefrCPlCr 46
           C++C+e+f+d  ++l+CgH+f++dCl +       +g +  ++ +++CP+Cr
   Q: 16   CPVCYESFSDSARTLSCGHHFCHDCLVRTlvntslNGTN--KRDNIICPVCR 65
           **************************4445755333333..666679****8 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

LYPETGMDEE AQDSECPVCY ESFSDSARTL SCGHHFCHDC LVRTLVNTSL NGTNKRDNII 60
CPVCRHLTFI TKQHGFTVST TESKRLGKTL EVPSVPTPEF PRNTTGSHTG GLECICWCLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCGCCAGAG TGTTTGTGTG TGTTTCCGCG GGCTGTTGTT GCTTATTAAC CGCGCGCTGC 60
GGCATCTCAA ATCCAGCTGA TCGAGCGCAT CCAGGCGGGG AGTTCTTTAC CCGGAGACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0033768--C:SUMO-targeted ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0033234--P:negative regulation of protein sumoylation
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001331	Ailuropoda melanoleuca	46.39	5.00e-18	83.20
IUUC-Apl-003509	Anas platyrhynchos	35.36	3.00e-18	85.50
IUUC-Aca-004916	Anolis carolinensis	48.48	8.00e-12	63.50
IUUC-Bta-013443	Bos taurus	40.20	5.00e-16	77.80
IUUC-Bci-013799	Botrytis cinerea	42.86	3.00e-05	43.10
IUUC-Cja-019637	Callithrix jacchus	35.26	8.00e-17	80.50
IUUC-Cfa-020737	Canis familiaris	49.38	9.00e-17	80.10
IUUC-Cpo-022224	Cavia porcellus	55.74	3.00e-16	78.60
IUUC-Csa-024175	Chlorocebus sabaeus	35.90	3.00e-17	82.00
IUUC-Dno-030024	Dasypus novemcinctus	36.84	2.00e-18	85.50
IUUC-Dor-030936	Dipodomys ordii	39.19	3.00e-19	88.20
IUUC-Eca-033759	Equus caballus	38.36	7.00e-21	94.00
IUUC-Fal-037142	Ficedula albicollis	36.55	5.00e-15	74.30
IUUC-Gmo-039196	Gadus morhua	48.58	6.00e-35	140.00
IUUC-Gga-041189	Gallus gallus	45.36	3.00e-18	85.10
IUUC-Gac-041497	Gasterosteus aculeatus	45.40	3.00e-30	124.00
IUUC-Ggo-045020	Gorilla gorilla	35.44	3.00e-18	85.10
IUUC-Hsa-046317	Homo sapiens	35.44	1.00e-17	83.20
IUUC-Itr-048656	Ictidomys tridecemlineatus	39.33	2.00e-21	95.90
IUUC-Lch-049885	Latimeria chalumnae	39.20	4.00e-22	97.80
IUUC-Laf-053457	Loxodonta africana	47.19	4.00e-18	84.70
IUUC-Mcc-054653	Macaca mulatta	36.54	2.00e-18	85.90
IUUC-Mga-059753	Meleagris gallopavo	45.36	5.00e-18	84.30
IUUC-Mdo-062993	Monodelphis domestica	32.71	2.00e-22	99.00
IUUC-Mmu-063225	Mus musculus	39.86	3.00e-20	91.70
IUUC-Mpu-066299	Mustela putorius furo	47.62	1.00e-16	79.70
IUUC-Mlu-066988	Myotis lucifugus	48.15	2.00e-16	79.00
IUUC-Nle-069011	Nomascus leucogenys	36.71	9.00e-19	87.00
IUUC-Opr-070258	Ochotona princeps	35.26	6.00e-17	80.90
IUUC-Ont-071886	Oreochromis niloticus	41.26	3.00e-31	127.00
IUUC-Ocu-074282	Oryctolagus cuniculus	37.16	3.00e-18	85.10
IUUC-Oga-088403	Otolemur garnettii	48.31	2.00e-18	85.90
IUUC-Oar-089665	Ovis aries	54.00	5.00e-10	55.50
IUUC-Ptr-090580	Pan troglodytes	36.08	6.00e-18	84.30
IUUC-Pan-092447	Papio anubis	36.54	1.00e-18	86.70
IUUC-Psi-093673	Pelodiscus sinensis	34.20	3.00e-19	88.20
IUUC-Pfo-096933	Poecilia formosa	45.68	2.00e-27	115.00
IUUC-Pab-097867	Pongo abelii	35.90	8.00e-18	83.60
IUUC-Pva-102146	Pteropus vampyrus	38.10	1.00e-17	82.80
IUUC-Rno-105897	Rattus norvegicus	38.00	8.00e-20	90.10
IUUC-Sha-107282	Sarcophilus harrisii	33.17	9.00e-18	83.60
IUUC-Sar-113260	Sorex araneus	41.50	2.00e-21	95.50
IUUC-Ssc-115449	Sus scrofa	55.74	2.00e-15	75.50
IUUC-Tgu-117349	Taeniopygia guttata	48.57	2.00e-15	75.10
IUUC-Vda-129777	Verticillium dahliae	37.04	7.00e-07	48.90
IUUC-Xtr-132180	Xenopus tropicalis	34.64	4.00e-18	84.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence