iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088378

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03106235

Gene Name

TRIM35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000027382.1	ENSOGAT00000025254.1	ENSOGAP00000019666.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.10e-06	28.1	21	61
E3 activity/RING/U-box	5.10e-09	36.1	16	86

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+C+++f+d  ++l+CgH f+++C+  +w     + +    CP+C+
   Q: 21   CAVCYDPFRD-AVTLRCGHNFCRECVsRCW-----EVQVVPACPVCK 61
           ********99.999************9999.....6778889****6 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrliqawceen 72
            ee+lC++ ++++rd v+l +G+ + r+++ ++ + +    cPv++ + +++dl  n+tl +l+++ ++e+
   Q: 16   KEELLCAVCYDPFRDAVTLRCGHNFCRECVSRCWEVQVVpACPVCKDRASPSDLRTNHTLNNLVEKLLHEE 86
           689*****************************996555558***********************9988775 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MEPIPDVSPG PSRSFKEELL CAVCYDPFRD AVTLRCGHNF CRECVSRCWE VQVVPACPVC 60
KDRASPSDLR TNHTLNNLVE KLLHEEAEGA PWTGRHSQRL CRPHRGQLSL FCLEDKELLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCCGA TCCCGGATGT GTCTCCTGGG CCTTCCCGAT CTTTCAAGGA AGAGCTGCTG 60
TGTGCCGTGT GCTACGACCC CTTCCGCGAC GCGGTGACTC TGCGCTGCGG CCACAACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0045930--P:negative regulation of mitotic cell cycle
GO:1902187--P:negative regulation of viral release from host cell
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001788	Ailuropoda melanoleuca	86.41	0.00e+00	877.00
IUUC-Apl-003958	Anas platyrhynchos	53.77	6.00e-130	457.00
IUUC-Aca-005199	Anolis carolinensis	46.25	6.00e-120	424.00
IUUC-Ame-011964	Astyanax mexicanus	35.64	5.00e-71	261.00
IUUC-Bta-013359	Bos taurus	85.45	0.00e+00	848.00
IUUC-Cja-018900	Callithrix jacchus	77.40	0.00e+00	764.00
IUUC-Cfa-020685	Canis familiaris	87.02	0.00e+00	887.00
IUUC-Cpo-022253	Cavia porcellus	77.28	0.00e+00	752.00
IUUC-Csa-023777	Chlorocebus sabaeus	90.06	0.00e+00	907.00
IUUC-Dre-028185	Danio rerio	36.55	3.00e-58	219.00
IUUC-Dno-029065	Dasypus novemcinctus	85.42	0.00e+00	860.00
IUUC-Dor-030248	Dipodomys ordii	64.75	2.00e-98	352.00
IUUC-Ete-033183	Echinops telfairi	72.62	0.00e+00	700.00
IUUC-Eca-033263	Equus caballus	86.09	0.00e+00	767.00
IUUC-Eeu-034699	Erinaceus europaeus	77.41	2.00e-110	392.00
IUUC-Fca-036366	Felis catus	85.60	0.00e+00	870.00
IUUC-Fal-037257	Ficedula albicollis	56.78	1.00e-153	536.00
IUUC-Gmo-038512	Gadus morhua	34.43	3.00e-67	248.00
IUUC-Gga-041125	Gallus gallus	53.67	1.00e-101	362.00
IUUC-Gac-041608	Gasterosteus aculeatus	31.79	4.00e-62	232.00
IUUC-Ggo-045233	Gorilla gorilla	89.84	1.00e-166	578.00
IUUC-Hsa-046042	Homo sapiens	89.66	0.00e+00	905.00
IUUC-Itr-048751	Ictidomys tridecemlineatus	86.25	0.00e+00	854.00
IUUC-Lch-049548	Latimeria chalumnae	35.48	3.00e-81	295.00
IUUC-Laf-054322	Loxodonta africana	87.03	0.00e+00	862.00
IUUC-Mcc-055555	Macaca mulatta	87.58	0.00e+00	885.00
IUUC-Meu-055900	Macropus eugenii	76.89	0.00e+00	758.00
IUUC-Mga-059380	Meleagris gallopavo	55.21	2.00e-101	362.00
IUUC-Mmr-061296	Microcebus murinus	87.22	0.00e+00	878.00
IUUC-Mdo-062811	Monodelphis domestica	77.19	0.00e+00	763.00
IUUC-Mmu-063718	Mus musculus	77.57	0.00e+00	780.00
IUUC-Mpu-066219	Mustela putorius furo	86.69	0.00e+00	863.00
IUUC-Mlu-067033	Myotis lucifugus	82.15	0.00e+00	841.00
IUUC-Nle-069806	Nomascus leucogenys	90.17	0.00e+00	844.00
IUUC-Opr-070248	Ochotona princeps	78.31	0.00e+00	753.00
IUUC-Ont-072083	Oreochromis niloticus	32.79	1.00e-68	254.00
IUUC-Oan-073364	Ornithorhynchus anatinus	69.80	2.00e-99	355.00
IUUC-Ocu-074572	Oryctolagus cuniculus	89.63	0.00e+00	904.00
IUUC-Oar-089516	Ovis aries	84.58	0.00e+00	836.00
IUUC-Ptr-091313	Pan troglodytes	89.66	0.00e+00	905.00
IUUC-Pan-092877	Papio anubis	89.86	0.00e+00	906.00
IUUC-Psi-093928	Pelodiscus sinensis	57.74	1.00e-156	546.00
IUUC-Pfo-096690	Poecilia formosa	33.90	2.00e-68	253.00
IUUC-Pab-098624	Pongo abelii	89.25	0.00e+00	897.00
IUUC-Pca-100469	Procavia capensis	78.71	0.00e+00	779.00
IUUC-Pva-103227	Pteropus vampyrus	86.00	0.00e+00	875.00
IUUC-Rno-105778	Rattus norvegicus	77.37	0.00e+00	781.00
IUUC-Sha-107392	Sarcophilus harrisii	66.20	0.00e+00	639.00
IUUC-Sar-113297	Sorex araneus	73.64	2.00e-52	199.00
IUUC-Ssc-115739	Sus scrofa	85.24	0.00e+00	839.00
IUUC-Tru-117718	Takifugu rubripes	31.63	1.00e-61	230.00
IUUC-Tbe-127926	Tupaia belangeri	81.85	3.00e-126	445.00
IUUC-Ttr-129293	Tursiops truncatus	85.60	0.00e+00	860.00
IUUC-Vpa-130379	Vicugna pacos	86.24	5.00e-148	516.00
IUUC-Xma-134222	Xiphophorus maculatus	32.77	5.00e-61	228.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence