iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065956

Ensembl Protein ID

ENSMPUP00000002600.1

UniProt Accession

M3XU50; M3XU50_MUSPF

Genbank Protein ID

ENSMPUP00000002600

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01037573

Gene Name

TRAF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000002628.1	ENSMPUT00000002654.1	ENSMPUP00000002600.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	94.02	0.00e+00	1088.00	IUUC-Hsa-046957

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MEPSKKLDPP GTLPPNPPLK LHPDRGATST SVFVPEQGGY KERFVKTVED KYKCEKCRLV 60
LCNPKQTECG HRFCETCMAA LLSSSSPKCT ACQEGIIKDK VFKDNCCKRE ILALQIYCRN 120

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Nucleotide Sequence
(Fasta)

GTTTCTCCAG CCGTTATTTA AAAGTTTATA CTGAGTCATT GCTCTGCAGA CGGAGCTCTG 60
ACGGATCCCC GAGCGGGCCG CTGCAGTGGC CTCGAAGGCA GGGCGCCCTG GGCTGCCGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027128--TRAF3
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00061--MATH

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0042981--P:regulation of apoptotic process
GO:0050688--P:regulation of defense response to virus
GO:0032648--P:regulation of interferon-beta production
GO:0030162--P:regulation of proteolysis
GO:0008063--P:Toll signaling pathway
GO:0002224--P:toll-like receptor signaling pathway
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002362	Ailuropoda melanoleuca	97.89	0.00e+00	1136.00
IUUC-Apl-004189	Anas platyrhynchos	89.27	0.00e+00	1047.00
IUUC-Aca-004540	Anolis carolinensis	87.01	0.00e+00	1008.00
IUUC-Ame-010645	Astyanax mexicanus	57.96	0.00e+00	650.00
IUUC-Bta-013140	Bos taurus	95.61	0.00e+00	1114.00
IUUC-Cja-019436	Callithrix jacchus	94.55	0.00e+00	1102.00
IUUC-Cfa-021072	Canis familiaris	96.84	0.00e+00	1127.00
IUUC-Cpo-022472	Cavia porcellus	94.90	0.00e+00	1112.00
IUUC-Csa-024217	Chlorocebus sabaeus	94.20	0.00e+00	1101.00
IUUC-Cho-025066	Choloepus hoffmanni	82.48	0.00e+00	807.00
IUUC-Cin-025234	Ciona intestinalis	29.57	5.00e-54	205.00
IUUC-Csv-026078	Ciona savignyi	68.54	7.00e-80	289.00
IUUC-Dre-028208	Danio rerio	57.41	3.00e-176	611.00
IUUC-Dno-028868	Dasypus novemcinctus	93.67	0.00e+00	1099.00
IUUC-Dor-031056	Dipodomys ordii	96.09	0.00e+00	978.00
IUUC-Ete-033005	Echinops telfairi	82.09	0.00e+00	786.00
IUUC-Eca-033717	Equus caballus	96.13	0.00e+00	1125.00
IUUC-Eeu-035172	Erinaceus europaeus	82.32	4.00e-176	610.00
IUUC-Fca-035688	Felis catus	97.37	0.00e+00	1130.00
IUUC-Fal-037176	Ficedula albicollis	89.09	0.00e+00	1045.00
IUUC-Gmo-038931	Gadus morhua	55.87	1.00e-169	589.00
IUUC-Gac-042019	Gasterosteus aculeatus	57.27	1.00e-177	616.00
IUUC-Ggo-044424	Gorilla gorilla	94.38	0.00e+00	1102.00
IUUC-Hsa-046957	Homo sapiens	94.02	0.00e+00	1098.00
IUUC-Itr-048352	Ictidomys tridecemlineatus	94.55	0.00e+00	1105.00
IUUC-Lch-050680	Latimeria chalumnae	69.61	0.00e+00	820.00
IUUC-Loc-052093	Lepisosteus oculatus	59.78	0.00e+00	688.00
IUUC-Laf-054573	Loxodonta africana	86.47	0.00e+00	990.00
IUUC-Mcc-055049	Macaca mulatta	93.85	0.00e+00	1098.00
IUUC-Mga-059244	Meleagris gallopavo	88.55	0.00e+00	1043.00
IUUC-Mmr-061469	Microcebus murinus	95.25	0.00e+00	1113.00
IUUC-Mdo-063049	Monodelphis domestica	91.56	0.00e+00	1082.00
IUUC-Mmu-063763	Mus musculus	95.08	0.00e+00	1108.00
IUUC-Mlu-067482	Myotis lucifugus	92.44	0.00e+00	1090.00
IUUC-Nle-069941	Nomascus leucogenys	94.55	0.00e+00	1105.00
IUUC-Opr-071027	Ochotona princeps	80.49	0.00e+00	880.00
IUUC-Ont-071914	Oreochromis niloticus	57.91	0.00e+00	658.00
IUUC-Oan-072802	Ornithorhynchus anatinus	91.39	0.00e+00	1073.00
IUUC-Ocu-074075	Oryctolagus cuniculus	94.90	0.00e+00	1111.00
IUUC-Oga-088149	Otolemur garnettii	95.25	0.00e+00	1114.00
IUUC-Oar-089922	Ovis aries	91.62	0.00e+00	1055.00
IUUC-Ptr-091412	Pan troglodytes	94.20	0.00e+00	1099.00
IUUC-Pan-092789	Papio anubis	94.20	0.00e+00	1101.00
IUUC-Psi-093603	Pelodiscus sinensis	88.31	0.00e+00	1022.00
IUUC-Pma-094463	Petromyzon marinus	50.00	2.00e-140	492.00
IUUC-Pfo-096518	Poecilia formosa	56.09	0.00e+00	642.00
IUUC-Pab-097664	Pongo abelii	94.38	0.00e+00	1102.00
IUUC-Pca-100821	Procavia capensis	84.77	0.00e+00	848.00
IUUC-Pva-103201	Pteropus vampyrus	83.30	0.00e+00	956.00
IUUC-Rno-105505	Rattus norvegicus	95.08	0.00e+00	1116.00
IUUC-Sha-107416	Sarcophilus harrisii	91.39	0.00e+00	1076.00
IUUC-Sar-113438	Sorex araneus	93.55	2.00e-100	358.00
IUUC-Ssc-115351	Sus scrofa	95.43	0.00e+00	1117.00
IUUC-Tgu-116608	Taeniopygia guttata	89.27	0.00e+00	1045.00
IUUC-Tru-117964	Takifugu rubripes	57.36	0.00e+00	626.00
IUUC-Tni-120211	Tetraodon nigroviridis	55.99	0.00e+00	634.00
IUUC-Tbe-127700	Tupaia belangeri	76.32	2.00e-132	466.00
IUUC-Ttr-128450	Tursiops truncatus	93.15	1.00e-172	598.00
IUUC-Vda-129938	Verticillium dahliae	25.59	2.00e-18	87.40
IUUC-Vpa-130074	Vicugna pacos	97.73	0.00e+00	895.00
IUUC-Xtr-132563	Xenopus tropicalis	81.09	0.00e+00	954.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence