iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003965

Ensembl Protein ID

ENSAPLP00000000671.1

UniProt Accession

U3I0A1; U3I0A1_ANAPL

Genbank Protein ID

ENSAPLP00000000671

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01065904

Gene Name

KLHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000000978.1	ENSAPLT00000001242.1	ENSAPLP00000000671.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.80e-22	76.8	49	115
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.00e-10	40.7	148	179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv++v + +e +ah++vLaa+S++F a+f+++++esk  +++eikdv+ + +r l++++Yt +++ +
   Q: 49   CDVVIVAETVEMEAHRVVLAACSPYFCAMFTGDMSESK-AKKIEIKDVDGQTLRKLIDYIYTAEIEVT 115
           8*************************************.************************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nclgi++fAd + c++L ++a+ ++++hF+
   Q: 148  PTNCLGIRAFADVHACTELLQQANAYAEQHFP 179
           78*****************************6 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

VPVFSIKQSS RSSEAAEDEK EQRTVTVNPS HMRKAFKVMN ELRSKRLLCD VVIVAETVEM 60
EAHRVVLAAC SPYFCAMFTG DMSESKAKKI EIKDVDGQTL RKLIDYIYTA EIEVTEENVQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCCTGTTT TCAGCATTAA GCAGAGTTCC CGATCCTCTG AGGCAGCTGA GGATGAAAAG 60
GAGCAGCGCA CAGTGACAGT CAACCCCTCT CACATGAGAA AGGCGTTCAA GGTCATGAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0072156--P:distal tubule morphogenesis
GO:0050801--P:ion homeostasis
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0070294--P:renal sodium ion absorption

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001632	Ailuropoda melanoleuca	94.57	0.00e+00	1136.00
IUUC-Aca-004912	Anolis carolinensis	94.33	0.00e+00	1094.00
IUUC-Ate-010500	Aspergillus terreus	25.93	2.00e-20	93.20
IUUC-Ame-010670	Astyanax mexicanus	80.45	0.00e+00	943.00
IUUC-Bta-013354	Bos taurus	94.40	0.00e+00	1135.00
IUUC-Bol-016582	Brassica oleracea	30.28	3.00e-13	70.50
IUUC-Bra-017771	Brassica rapa	31.02	1.00e-13	72.00
IUUC-Cel-018136	Caenorhabditis elegans	42.47	2.00e-130	459.00
IUUC-Cja-019183	Callithrix jacchus	91.19	0.00e+00	1003.00
IUUC-Cfa-020465	Canis familiaris	93.34	0.00e+00	1118.00
IUUC-Cpo-022115	Cavia porcellus	94.17	0.00e+00	1129.00
IUUC-Csa-024219	Chlorocebus sabaeus	94.85	0.00e+00	1134.00
IUUC-Csv-026032	Ciona savignyi	60.77	0.00e+00	706.00
IUUC-Cgl-026620	Colletotrichum gloeosporioides	30.42	6.00e-24	104.00
IUUC-Dre-028524	Danio rerio	74.08	0.00e+00	947.00
IUUC-Dno-029075	Dasypus novemcinctus	96.62	0.00e+00	1118.00
IUUC-Dor-030156	Dipodomys ordii	78.90	0.00e+00	914.00
IUUC-Ete-033064	Echinops telfairi	80.23	0.00e+00	822.00
IUUC-Eca-033887	Equus caballus	93.83	0.00e+00	1118.00
IUUC-Eeu-035244	Erinaceus europaeus	75.13	0.00e+00	881.00
IUUC-Fca-035375	Felis catus	93.89	0.00e+00	1127.00
IUUC-Fal-037119	Ficedula albicollis	99.28	0.00e+00	1100.00
IUUC-Fso-038219	Fusarium solani	38.71	1.00e-09	53.50
IUUC-Gga-041094	Gallus gallus	99.48	0.00e+00	1138.00
IUUC-Gac-042585	Gasterosteus aculeatus	77.51	0.00e+00	916.00
IUUC-Ggo-045485	Gorilla gorilla	94.20	0.00e+00	1123.00
IUUC-Hsa-046717	Homo sapiens	94.68	0.00e+00	1133.00
IUUC-Itr-048605	Ictidomys tridecemlineatus	94.55	0.00e+00	1140.00
IUUC-Lch-050246	Latimeria chalumnae	87.83	0.00e+00	1004.00
IUUC-Laf-053700	Loxodonta africana	93.97	0.00e+00	1110.00
IUUC-Mcc-054732	Macaca mulatta	97.23	0.00e+00	1006.00
IUUC-Mga-059994	Meleagris gallopavo	99.06	0.00e+00	1043.00
IUUC-Mdo-062923	Monodelphis domestica	94.85	0.00e+00	1133.00
IUUC-Mmu-063842	Mus musculus	94.35	0.00e+00	1123.00
IUUC-Mpu-066380	Mustela putorius furo	94.85	0.00e+00	1130.00
IUUC-Mlu-067922	Myotis lucifugus	94.66	0.00e+00	1119.00
IUUC-Nle-069761	Nomascus leucogenys	94.68	0.00e+00	1132.00
IUUC-Opr-070287	Ochotona princeps	86.60	0.00e+00	1009.00
IUUC-Ont-071654	Oreochromis niloticus	79.65	0.00e+00	957.00
IUUC-Ocu-074957	Oryctolagus cuniculus	93.69	0.00e+00	1114.00
IUUC-Ola-086853	Oryzias latipes	78.96	0.00e+00	915.00
IUUC-Oga-088559	Otolemur garnettii	94.19	0.00e+00	1122.00
IUUC-Oar-089925	Ovis aries	94.87	0.00e+00	1131.00
IUUC-Ptr-091487	Pan troglodytes	94.68	0.00e+00	1133.00
IUUC-Pan-091705	Papio anubis	94.85	0.00e+00	1134.00
IUUC-Psi-093478	Pelodiscus sinensis	92.53	0.00e+00	1056.00
IUUC-Pfo-097450	Poecilia formosa	79.83	0.00e+00	900.00
IUUC-Pab-097618	Pongo abelii	94.51	0.00e+00	1130.00
IUUC-Pca-100739	Procavia capensis	87.73	0.00e+00	653.00
IUUC-Sha-106935	Sarcophilus harrisii	97.60	0.00e+00	749.00
IUUC-Ssc-115599	Sus scrofa	95.02	0.00e+00	1132.00
IUUC-Tgu-117001	Taeniopygia guttata	99.29	0.00e+00	1122.00
IUUC-Tru-118078	Takifugu rubripes	78.78	0.00e+00	951.00
IUUC-Tsy-119161	Tarsius syrichta	82.77	0.00e+00	867.00
IUUC-Tni-120888	Tetraodon nigroviridis	75.47	0.00e+00	891.00
IUUC-Tbe-127285	Tupaia belangeri	80.87	0.00e+00	645.00
IUUC-Ttr-128884	Tursiops truncatus	78.40	3.00e-144	504.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence