iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062654

Ensembl Protein ID

ENSMODP00000017597.3

UniProt Accession

F6TST1; F6TST1_MONDO

Protein Name

Uncharacterized protein

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000014073.3	ENSMODT00000017923.3	ENSMODP00000017597.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.30e-14	52.7	165	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL+  kGd+++v     +++gW++g  +l+gk G fP+n+v++++
   Q: 165  VVRARFNFKQTNEDELSVCKGDIIYVT--RVEEGGWWEG--TLNGKTGWFPSNYVREIK 219
           68999*********************7..999*******..8**************996 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MNPEERIVTW LISLGVLNSP KKTICDPEEF LKVSLKNGVV LCKLLNRLVP GAVEKHCQEP 60
QTEADCISNI KDFLKGCACL QVEVFDPCDL YTGNNFSRVL STLLAVNKAT EDYQVSERPC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCCCAGCA GCCCCGAGCG TGGTCTCCAG TTCCGTGAGA AGATCCCACC TCTGGAGTAG 60
AGGTCCTGCC GTGGCCTGAG AAGGCTCGTC TCCACTGTTT GCTCAGCAAG CGCCAGGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

KEGG

mdo:100010264

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	70.80	0.00e+00	1098.00
IUUC-Apl-003960	Anas platyrhynchos	78.02	0.00e+00	1127.00
IUUC-Aca-004988	Anolis carolinensis	72.18	0.00e+00	1029.00
IUUC-Ame-011546	Astyanax mexicanus	65.30	0.00e+00	937.00
IUUC-Bta-013527	Bos taurus	80.21	0.00e+00	1197.00
IUUC-Cja-018935	Callithrix jacchus	79.18	0.00e+00	1154.00
IUUC-Cfa-021269	Canis familiaris	79.56	0.00e+00	1167.00
IUUC-Cpo-021620	Cavia porcellus	76.37	0.00e+00	1117.00
IUUC-Csa-023415	Chlorocebus sabaeus	78.92	0.00e+00	1155.00
IUUC-Dre-028580	Danio rerio	64.90	0.00e+00	973.00
IUUC-Dno-029201	Dasypus novemcinctus	75.99	0.00e+00	1167.00
IUUC-Dor-030868	Dipodomys ordii	65.17	0.00e+00	867.00
IUUC-Eca-033500	Equus caballus	80.33	0.00e+00	1176.00
IUUC-Eeu-035269	Erinaceus europaeus	71.63	2.00e-142	499.00
IUUC-Fca-035683	Felis catus	79.08	0.00e+00	1148.00
IUUC-Fal-037611	Ficedula albicollis	78.15	0.00e+00	1120.00
IUUC-Gmo-038980	Gadus morhua	61.00	0.00e+00	900.00
IUUC-Gga-040940	Gallus gallus	76.48	0.00e+00	1110.00
IUUC-Gac-042203	Gasterosteus aculeatus	62.77	0.00e+00	942.00
IUUC-Ggo-044755	Gorilla gorilla	79.05	0.00e+00	1153.00
IUUC-Hsa-046210	Homo sapiens	78.92	0.00e+00	1153.00
IUUC-Lch-049517	Latimeria chalumnae	70.63	0.00e+00	1021.00
IUUC-Loc-052393	Lepisosteus oculatus	64.97	0.00e+00	991.00
IUUC-Laf-054196	Loxodonta africana	79.15	0.00e+00	1128.00
IUUC-Mcc-055716	Macaca mulatta	78.92	0.00e+00	1155.00
IUUC-Meu-056285	Macropus eugenii	85.53	0.00e+00	785.00
IUUC-Mtr-058576	Medicago truncatula	44.44	1.00e-10	60.50
IUUC-Mga-060029	Meleagris gallopavo	77.25	0.00e+00	1131.00
IUUC-Mmr-060803	Microcebus murinus	79.31	0.00e+00	1155.00
IUUC-Mmu-063479	Mus musculus	78.43	0.00e+00	1137.00
IUUC-Mpu-066065	Mustela putorius furo	79.69	0.00e+00	1151.00
IUUC-Mlu-068222	Myotis lucifugus	78.43	0.00e+00	1137.00
IUUC-Nle-069379	Nomascus leucogenys	79.18	0.00e+00	1155.00
IUUC-Opr-070687	Ochotona princeps	63.45	0.00e+00	708.00
IUUC-Oan-073067	Ornithorhynchus anatinus	82.52	0.00e+00	1223.00
IUUC-Ocu-074852	Oryctolagus cuniculus	79.82	0.00e+00	1163.00
IUUC-Oga-089048	Otolemur garnettii	74.08	0.00e+00	986.00
IUUC-Oar-089339	Ovis aries	80.33	0.00e+00	1196.00
IUUC-Pan-092666	Papio anubis	76.41	0.00e+00	1109.00
IUUC-Psi-093116	Pelodiscus sinensis	77.61	0.00e+00	1144.00
IUUC-Pfo-097394	Poecilia formosa	63.17	0.00e+00	920.00
IUUC-Pab-098567	Pongo abelii	79.05	0.00e+00	1155.00
IUUC-Pca-100997	Procavia capensis	69.63	0.00e+00	951.00
IUUC-Pva-102500	Pteropus vampyrus	77.63	0.00e+00	1109.00
IUUC-Rno-104974	Rattus norvegicus	79.31	0.00e+00	1120.00
IUUC-Sar-113420	Sorex araneus	76.86	0.00e+00	1101.00
IUUC-Ssc-115679	Sus scrofa	79.11	0.00e+00	1019.00
IUUC-Tgu-117069	Taeniopygia guttata	75.84	0.00e+00	1099.00
IUUC-Tsy-119243	Tarsius syrichta	70.88	0.00e+00	782.00
IUUC-Tni-120584	Tetraodon nigroviridis	60.95	0.00e+00	906.00
IUUC-Tbe-127994	Tupaia belangeri	65.42	0.00e+00	945.00
IUUC-Ttr-128839	Tursiops truncatus	78.79	0.00e+00	1134.00
IUUC-Vpa-130144	Vicugna pacos	72.88	0.00e+00	1006.00
IUUC-Xtr-132624	Xenopus tropicalis	70.47	0.00e+00	1068.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence