iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054513

UUCD1 version

UUC-LoA-00553

Ensembl Protein ID

ENSLAFP00000013331.3

UniProt Accession

G3TFX6; G3TFX6_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000015896.3	ENSLAFT00000015895.3	ENSLAFP00000013331.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.90e-17	62.8	66	131
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.70e-09	36.8	165	196

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+vLa   ++F+a+fl+e+ e k +  +ei+d + ++ ++l+kF+Y+++l++
   Q: 66   CDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAK-QTLIEIRDFDGDAIEDLVKFVYSSRLTL 131
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a+ +++ hF+
   Q: 165  PSNCLAVRAFAESHNRIDLMDMADQYACEHFT 196
           89*****************************7 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MASEPGSAKQ ARSPFTKGKR QQYQQIKNRS SVSDGDGDDS FIFEANEAWK DFHGSLLRFY 60
ENGELCDVTL KVGSKLISCH KLVLACVIPY FRAMFLSEMA EAKQTLIEIR DFDGDAIEDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCAG AACCTGGGAG TGCAAAACAA GCTAGAAGTC CCTTCACAAA GGGGAAACGG 60
CAGCAGTACC AGCAAATAAA GAACAGATCT TCAGTTAGTG ATGGTGATGG AGATGACTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

lav:100672158

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	96.93	0.00e+00	1233.00
IUUC-Atr-002726	Amborella trichopoda	36.17	3.00e-43	170.00
IUUC-Apl-003978	Anas platyrhynchos	89.52	0.00e+00	1155.00
IUUC-Aca-004958	Anolis carolinensis	85.00	0.00e+00	1080.00
IUUC-Ame-011139	Astyanax mexicanus	84.60	0.00e+00	1065.00
IUUC-Bta-013142	Bos taurus	96.28	0.00e+00	1222.00
IUUC-Cel-018551	Caenorhabditis elegans	40.30	2.00e-130	459.00
IUUC-Cja-019650	Callithrix jacchus	95.48	0.00e+00	1241.00
IUUC-Cfa-021046	Canis familiaris	97.09	0.00e+00	1231.00
IUUC-Cpo-022445	Cavia porcellus	93.70	0.00e+00	1168.00
IUUC-Csa-023642	Chlorocebus sabaeus	96.45	0.00e+00	1252.00
IUUC-Cho-025012	Choloepus hoffmanni	79.72	0.00e+00	894.00
IUUC-Dre-027723	Danio rerio	82.11	0.00e+00	1058.00
IUUC-Dno-028964	Dasypus novemcinctus	95.70	0.00e+00	1020.00
IUUC-Dor-030899	Dipodomys ordii	81.79	6.00e-135	474.00
IUUC-Ete-032815	Echinops telfairi	94.02	0.00e+00	1221.00
IUUC-Eca-034162	Equus caballus	96.77	0.00e+00	1206.00
IUUC-Eeu-034660	Erinaceus europaeus	94.35	0.00e+00	1197.00
IUUC-Fca-035659	Felis catus	97.58	0.00e+00	1239.00
IUUC-Fal-037619	Ficedula albicollis	89.98	0.00e+00	1164.00
IUUC-Gmo-038546	Gadus morhua	84.93	0.00e+00	1053.00
IUUC-Gga-040770	Gallus gallus	90.00	0.00e+00	1133.00
IUUC-Gac-042557	Gasterosteus aculeatus	81.76	0.00e+00	1039.00
IUUC-Ggo-044741	Gorilla gorilla	96.29	0.00e+00	1251.00
IUUC-Hsa-046025	Homo sapiens	96.45	0.00e+00	1252.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	97.81	0.00e+00	1105.00
IUUC-Loc-052834	Lepisosteus oculatus	83.58	0.00e+00	1014.00
IUUC-Mcc-054707	Macaca mulatta	96.29	0.00e+00	1248.00
IUUC-Meu-056779	Macropus eugenii	89.55	0.00e+00	1153.00
IUUC-Mga-059676	Meleagris gallopavo	89.84	0.00e+00	1132.00
IUUC-Mmr-061359	Microcebus murinus	95.65	0.00e+00	1207.00
IUUC-Mdo-062527	Monodelphis domestica	88.60	0.00e+00	1149.00
IUUC-Mmu-063112	Mus musculus	92.37	0.00e+00	1209.00
IUUC-Mac-064682	Musa acuminata	35.50	4.00e-41	162.00
IUUC-Mpu-065800	Mustela putorius furo	96.45	0.00e+00	1228.00
IUUC-Mlu-067536	Myotis lucifugus	95.28	0.00e+00	1172.00
IUUC-Nle-069397	Nomascus leucogenys	96.29	0.00e+00	1250.00
IUUC-Opr-070599	Ochotona princeps	94.91	0.00e+00	1018.00
IUUC-Ont-072580	Oreochromis niloticus	81.46	0.00e+00	1056.00
IUUC-Oan-073180	Ornithorhynchus anatinus	90.31	0.00e+00	1159.00
IUUC-Ocu-074026	Oryctolagus cuniculus	96.28	0.00e+00	1202.00
IUUC-Ola-086776	Oryzias latipes	80.56	0.00e+00	1016.00
IUUC-Oga-088651	Otolemur garnettii	96.14	0.00e+00	1215.00
IUUC-Oar-089567	Ovis aries	95.15	0.00e+00	1198.00
IUUC-Ptr-091564	Pan troglodytes	96.29	0.00e+00	1251.00
IUUC-Pan-092578	Papio anubis	96.45	0.00e+00	1252.00
IUUC-Psi-093635	Pelodiscus sinensis	88.76	0.00e+00	1096.00
IUUC-Pma-094660	Petromyzon marinus	61.30	0.00e+00	754.00
IUUC-Pfo-097507	Poecilia formosa	81.24	0.00e+00	984.00
IUUC-Pab-098025	Pongo abelii	96.29	0.00e+00	1251.00
IUUC-Pca-101046	Procavia capensis	86.85	0.00e+00	632.00
IUUC-Ppe-101154	Prunus persica	32.28	2.00e-38	154.00
IUUC-Pva-102359	Pteropus vampyrus	97.50	0.00e+00	904.00
IUUC-Rno-105750	Rattus norvegicus	93.08	0.00e+00	1186.00
IUUC-Sha-107513	Sarcophilus harrisii	91.45	0.00e+00	1187.00
IUUC-Sly-111482	Solanum lycopersicum	31.91	3.00e-41	163.00
IUUC-Stu-112032	Solanum tuberosum	33.07	2.00e-42	167.00
IUUC-Sar-113616	Sorex araneus	70.99	5.00e-118	417.00
IUUC-Ssc-116205	Sus scrofa	96.29	0.00e+00	1033.00
IUUC-Tgu-117435	Taeniopygia guttata	89.82	0.00e+00	1157.00
IUUC-Tru-118709	Takifugu rubripes	80.49	0.00e+00	1054.00
IUUC-Tsy-119466	Tarsius syrichta	98.36	0.00e+00	1107.00
IUUC-Tni-119988	Tetraodon nigroviridis	80.19	0.00e+00	1048.00
IUUC-Tbe-127704	Tupaia belangeri	96.17	0.00e+00	1062.00
IUUC-Ttr-128892	Tursiops truncatus	97.62	0.00e+00	924.00
IUUC-Vpa-130545	Vicugna pacos	97.26	0.00e+00	1041.00
IUUC-Xtr-132289	Xenopus tropicalis	83.30	0.00e+00	1028.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence