iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067714

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02020422

Gene Name

SKP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000002682.2	ENSMLUT00000002682.2	ENSMLUP00000002437.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	29.45	4.00e-29	125.00	IUUC-Cel-018410
E3 adaptor/Cullin RING/SCF/F-box	88.47	0.00e+00	749.00	IUUC-Hsa-046512
E3 adaptor/Cullin RING/SCF/F-box	55.37	2.00e-118	423.00	IUUC-Ots-000025

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

FCRKHLQEIP DQSSNVATTS FTWGWDSSKT SELLSGMGVS ALEKERVDSE NIPQELLSNL 60
GHPQGSPRKR LKSKGNDKDF VIIRRPKLNR ENFPGVSWDS LPDELLLGIF SCLCLPELLH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTGCAGGA AACACCTCCA GGAGATTCCC GACCAGTCGA GCAACGTGGC CACCACCAGC 60
TTCACTTGGG GATGGGATTC TAGCAAGACT TCGGAGCTGC TGTCAGGCAT GGGGGTCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0033148--P:positive regulation of intracellular estrogen receptor signaling pathway
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051726--P:regulation of cell cycle
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002197	Ailuropoda melanoleuca	91.76	0.00e+00	754.00
IUUC-Apl-003453	Anas platyrhynchos	66.27	1.00e-111	395.00
IUUC-Aca-005185	Anolis carolinensis	59.86	1.00e-134	473.00
IUUC-Ame-010665	Astyanax mexicanus	47.89	4.00e-86	311.00
IUUC-Bta-013450	Bos taurus	88.24	0.00e+00	762.00
IUUC-Cel-018410	Caenorhabditis elegans	29.45	4.00e-27	115.00
IUUC-Cja-019834	Callithrix jacchus	88.47	0.00e+00	749.00
IUUC-Cfa-020401	Canis familiaris	92.00	0.00e+00	785.00
IUUC-Cpo-022183	Cavia porcellus	88.99	0.00e+00	753.00
IUUC-Csa-023418	Chlorocebus sabaeus	88.71	0.00e+00	751.00
IUUC-Cho-024412	Choloepus hoffmanni	85.07	1.00e-170	592.00
IUUC-Cin-025248	Ciona intestinalis	31.00	1.00e-38	154.00
IUUC-Csv-026189	Ciona savignyi	31.64	9.00e-35	141.00
IUUC-Dre-028032	Danio rerio	47.75	3.00e-100	358.00
IUUC-Dno-029222	Dasypus novemcinctus	87.53	0.00e+00	744.00
IUUC-Dor-030505	Dipodomys ordii	85.07	7.00e-163	566.00
IUUC-Dme-031972	Drosophila melanogaster	33.14	5.00e-49	189.00
IUUC-Ete-032234	Echinops telfairi	81.68	1.00e-111	395.00
IUUC-Eca-033944	Equus caballus	92.24	0.00e+00	785.00
IUUC-Eeu-035008	Erinaceus europaeus	81.68	5.00e-114	403.00
IUUC-Fca-035412	Felis catus	91.53	0.00e+00	778.00
IUUC-Fal-037337	Ficedula albicollis	62.68	4.00e-135	474.00
IUUC-Gmo-038934	Gadus morhua	41.09	6.00e-38	151.00
IUUC-Gga-041152	Gallus gallus	65.00	3.00e-149	521.00
IUUC-Gac-041819	Gasterosteus aculeatus	44.33	2.00e-74	273.00
IUUC-Ggo-045479	Gorilla gorilla	88.17	3.00e-180	624.00
IUUC-Hsa-046512	Homo sapiens	88.47	0.00e+00	749.00
IUUC-Itr-048515	Ictidomys tridecemlineatus	90.46	0.00e+00	733.00
IUUC-Lch-050115	Latimeria chalumnae	56.67	2.00e-130	458.00
IUUC-Loc-052554	Lepisosteus oculatus	48.24	2.00e-100	359.00
IUUC-Laf-053563	Loxodonta africana	87.59	0.00e+00	716.00
IUUC-Mcc-055143	Macaca mulatta	88.99	0.00e+00	758.00
IUUC-Meu-056593	Macropus eugenii	56.79	2.00e-99	355.00
IUUC-Mga-060084	Meleagris gallopavo	58.56	2.00e-79	288.00
IUUC-Mmr-060660	Microcebus murinus	90.59	0.00e+00	772.00
IUUC-Mdo-062363	Monodelphis domestica	68.94	6.00e-153	533.00
IUUC-Mmu-063287	Mus musculus	82.82	0.00e+00	702.00
IUUC-Mpu-065791	Mustela putorius furo	90.82	0.00e+00	777.00
IUUC-Nle-069823	Nomascus leucogenys	88.94	0.00e+00	753.00
IUUC-Opr-071046	Ochotona princeps	73.15	2.00e-99	355.00
IUUC-Ont-071820	Oreochromis niloticus	44.62	5.00e-64	238.00
IUUC-Ocu-074868	Oryctolagus cuniculus	89.18	0.00e+00	754.00
IUUC-Ola-086608	Oryzias latipes	46.09	7.00e-72	264.00
IUUC-Oga-089044	Otolemur garnettii	89.88	0.00e+00	762.00
IUUC-Oar-089650	Ovis aries	88.71	0.00e+00	763.00
IUUC-Ptr-090743	Pan troglodytes	88.47	0.00e+00	749.00
IUUC-Pan-092501	Papio anubis	88.94	0.00e+00	753.00
IUUC-Psi-094032	Pelodiscus sinensis	65.72	2.00e-151	528.00
IUUC-Pfo-097279	Poecilia formosa	44.59	1.00e-61	230.00
IUUC-Pab-097821	Pongo abelii	89.01	0.00e+00	628.00
IUUC-Pca-100100	Procavia capensis	87.89	2.00e-169	588.00
IUUC-Pva-103181	Pteropus vampyrus	92.39	0.00e+00	635.00
IUUC-Rno-105091	Rattus norvegicus	84.87	0.00e+00	713.00
IUUC-Sha-107226	Sarcophilus harrisii	70.92	2.00e-162	565.00
IUUC-Ssc-115665	Sus scrofa	90.59	0.00e+00	775.00
IUUC-Tgu-116982	Taeniopygia guttata	61.59	2.00e-131	462.00
IUUC-Tru-118276	Takifugu rubripes	45.45	5.00e-69	254.00
IUUC-Tsy-119074	Tarsius syrichta	90.42	0.00e+00	637.00
IUUC-Tni-120702	Tetraodon nigroviridis	45.83	4.00e-47	181.00
IUUC-Tbe-127990	Tupaia belangeri	89.37	1.00e-152	532.00
IUUC-Ttr-128661	Tursiops truncatus	77.10	8.00e-110	390.00
IUUC-Xtr-132166	Xenopus tropicalis	55.21	2.00e-119	422.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence