iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012733

Ensembl Protein ID

ENSBTAP00000028871.5

UniProt Accession

F1MUR2; F1MUR2_BOVIN

Genbank Protein ID

ENSBTAP00000028871

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02043305

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000006175.5	ENSBTAT00000028871.5	ENSBTAP00000028871.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.60e-18	65.3	251	297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g++++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 251  VCLLCGSGSDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 297
           8*********88.6*******************.*******7.******5 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

FCKVRDPHDW QPPFACDVDK LHFTPRIQRL NELEAQTRVK LNFLDQIAKY WELQGSTLKI 60
PHVERKILDL FQLNKLVAEE GGFAVVCKDR KWTKIATKMG FAPGKAVGSH IRGHYERILN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTGTAAAG TGAGAGATCC TCATGGAAGA GAGGAGTGAG GGCCCCTTTT GCTTGGGTTG 60
GTGATCTTTC AGTGGCATCT TTCGATCCTG GTTGGAAGGG TGTGAAGAGG GGTGTGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000552	Aegilops tauschii	32.91	3.00e-100	360.00
IUUC-Aml-001963	Ailuropoda melanoleuca	91.88	0.00e+00	2657.00
IUUC-Apl-003770	Anas platyrhynchos	84.68	0.00e+00	2132.00
IUUC-Aca-004867	Anolis carolinensis	79.05	0.00e+00	2359.00
IUUC-Ame-010620	Astyanax mexicanus	62.67	0.00e+00	1847.00
IUUC-Bol-015336	Brassica oleracea	35.07	3.00e-14	75.50
IUUC-Cja-019050	Callithrix jacchus	91.31	0.00e+00	2694.00
IUUC-Cfa-021015	Canis familiaris	91.53	0.00e+00	2644.00
IUUC-Cpo-022340	Cavia porcellus	90.99	0.00e+00	2607.00
IUUC-Cre-022637	Chlamydomonas reinhardtii	48.21	7.00e-08	48.10
IUUC-Csa-023441	Chlorocebus sabaeus	91.85	0.00e+00	2654.00
IUUC-Cho-024823	Choloepus hoffmanni	96.01	0.00e+00	1612.00
IUUC-Cne-026851	Cryptococcus neoformans	29.48	3.00e-113	404.00
IUUC-Dre-027707	Danio rerio	60.29	0.00e+00	1758.00
IUUC-Dno-028978	Dasypus novemcinctus	91.58	0.00e+00	2656.00
IUUC-Dor-030854	Dipodomys ordii	81.94	0.00e+00	1824.00
IUUC-Ete-032760	Echinops telfairi	88.13	0.00e+00	1798.00
IUUC-Eca-034370	Equus caballus	91.73	0.00e+00	2580.00
IUUC-Eeu-035012	Erinaceus europaeus	74.17	0.00e+00	1831.00
IUUC-Fca-035494	Felis catus	92.14	0.00e+00	2649.00
IUUC-Fal-037631	Ficedula albicollis	80.96	0.00e+00	2349.00
IUUC-Gmo-039522	Gadus morhua	58.09	0.00e+00	1627.00
IUUC-Gga-040802	Gallus gallus	81.57	0.00e+00	2319.00
IUUC-Gac-041563	Gasterosteus aculeatus	60.48	0.00e+00	1748.00
IUUC-Gma-042675	Glycine max	33.13	7.00e-101	363.00
IUUC-Ggo-044856	Gorilla gorilla	74.68	0.00e+00	2030.00
IUUC-Hsa-045888	Homo sapiens	89.61	0.00e+00	2661.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	1.00e-15	78.60
IUUC-Itr-048297	Ictidomys tridecemlineatus	91.64	0.00e+00	2626.00
IUUC-Lch-050483	Latimeria chalumnae	64.24	0.00e+00	1893.00
IUUC-Lpe-051537	Leersia perrieri	31.83	9.00e-92	332.00
IUUC-Loc-052550	Lepisosteus oculatus	69.75	0.00e+00	1999.00
IUUC-Laf-053761	Loxodonta africana	90.72	0.00e+00	2602.00
IUUC-Mcc-055505	Macaca mulatta	89.74	0.00e+00	2663.00
IUUC-Mga-059358	Meleagris gallopavo	80.32	0.00e+00	2356.00
IUUC-Mmr-060863	Microcebus murinus	91.45	0.00e+00	2642.00
IUUC-Mdo-061957	Monodelphis domestica	85.83	0.00e+00	2537.00
IUUC-Mmu-063944	Mus musculus	89.82	0.00e+00	2610.00
IUUC-Mac-065069	Musa acuminata	36.04	2.00e-08	55.80
IUUC-Mpu-066719	Mustela putorius furo	89.68	0.00e+00	2637.00
IUUC-Mlu-068086	Myotis lucifugus	87.28	0.00e+00	2516.00
IUUC-Nle-069256	Nomascus leucogenys	89.67	0.00e+00	2661.00
IUUC-Ont-071756	Oreochromis niloticus	61.32	0.00e+00	1785.00
IUUC-Oan-073568	Ornithorhynchus anatinus	87.36	0.00e+00	2544.00
IUUC-Ocu-073961	Oryctolagus cuniculus	90.03	0.00e+00	2614.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	2.00e-16	81.60
IUUC-Olo-080668	Oryza longistaminata	38.83	5.00e-16	81.30
IUUC-Opu-083164	Oryza punctata	31.63	2.00e-88	321.00
IUUC-Osa-085487	Oryza sativa	38.83	2.00e-16	81.60
IUUC-Ola-086448	Oryzias latipes	60.30	0.00e+00	1749.00
IUUC-Oga-088501	Otolemur garnettii	87.27	0.00e+00	2258.00
IUUC-Oar-090162	Ovis aries	96.82	0.00e+00	2807.00
IUUC-Ptr-090816	Pan troglodytes	89.80	0.00e+00	2674.00
IUUC-Pan-092764	Papio anubis	91.91	0.00e+00	2658.00
IUUC-Psi-093918	Pelodiscus sinensis	80.22	0.00e+00	2160.00
IUUC-Pfo-096672	Poecilia formosa	60.34	0.00e+00	1722.00
IUUC-Pab-097854	Pongo abelii	90.57	0.00e+00	2071.00
IUUC-Pca-100241	Procavia capensis	85.74	0.00e+00	1696.00
IUUC-Pva-103035	Pteropus vampyrus	84.89	0.00e+00	2193.00
IUUC-Rno-105574	Rattus norvegicus	88.02	0.00e+00	2542.00
IUUC-Sce-106207	Saccharomyces cerevisiae	36.03	3.00e-73	270.00
IUUC-Sly-111298	Solanum lycopersicum	42.21	6.00e-102	366.00
IUUC-Sar-113477	Sorex araneus	88.63	0.00e+00	2366.00
IUUC-Ssc-116132	Sus scrofa	94.86	0.00e+00	2379.00
IUUC-Tgu-117452	Taeniopygia guttata	81.46	0.00e+00	2348.00
IUUC-Tru-117561	Takifugu rubripes	62.32	0.00e+00	1635.00
IUUC-Tsy-119271	Tarsius syrichta	90.04	0.00e+00	2076.00
IUUC-Tni-119650	Tetraodon nigroviridis	64.20	0.00e+00	1659.00
IUUC-Tur-126632	Triticum urartu	32.91	1.00e-99	358.00
IUUC-Tbe-127890	Tupaia belangeri	84.54	0.00e+00	1438.00
IUUC-Ttr-128546	Tursiops truncatus	91.39	0.00e+00	1974.00
IUUC-Vpa-130432	Vicugna pacos	91.27	0.00e+00	1592.00
IUUC-Vvi-131071	Vitis vinifera	31.30	2.00e-85	311.00
IUUC-Xtr-132008	Xenopus tropicalis	70.97	0.00e+00	2071.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence