iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	miRNAMap	RAID2
Protein-protein Interaction
IID	PINA
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.30e-07	30.3	62	136

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw.........pglknssskefr...............................CPlC 45
           C+ C++df++ p+vl+C H +++dC+  ++                    +                               CP+C
   Q: 62   CPYCQQDFRK-PRVLDCLHSMCEDCIiAQLdghlqaksaA----------IeekkrataamldceletpkvkerptppgvirCPIC 136
           ********99.**************953333333332220..........245555567777777777777777777777779999 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MKKAADRPTS AVNGRHESPA TSTNNTQNSG TPSLNGQDPL RSTSSSPLFG TEPLPEDDHA 60
SCPYCQQDFR KPRVLDCLHS MCEDCIIAQL DGHLQAKSAA IEEKKRATAA MLDCELETPK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCAGTTTA CACTCCAAGA GTGTCCCTGA TACTTTAATA TTCTCTTATT CTGTATTTGT 60
GTGCTTGTTA ATAACAAAAA GCACCCGGAT AAGAAGATTG AAAAGTGTCG AACGTTCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR003649--Bbox_C
IPR001258--NHL_repeat
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1

Pfam

PF01436--NHL
PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00502--BBC
SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0043186--C:P granule
GO:0000932--C:P-body
GO:0017151--F:DEAD/H-box RNA helicase binding
GO:0008270--F:zinc ion binding
GO:0045962--P:positive regulation of development, heterochronic
GO:0040034--P:regulation of development, heterochronic

KEGG

cel:CELE_F26F4.7

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002020	Ailuropoda melanoleuca	25.27	5.00e-23	101.00
IUUC-Apl-003894	Anas platyrhynchos	22.18	2.00e-14	73.20
IUUC-Ame-010865	Astyanax mexicanus	22.89	1.00e-17	83.20
IUUC-Bta-012744	Bos taurus	24.00	8.00e-21	94.00
IUUC-Cja-019162	Callithrix jacchus	22.79	2.00e-18	86.30
IUUC-Cfa-020163	Canis familiaris	24.64	3.00e-22	98.60
IUUC-Cpo-021833	Cavia porcellus	20.99	8.00e-16	78.60
IUUC-Csa-023746	Chlorocebus sabaeus	22.82	7.00e-20	90.90
IUUC-Cho-024414	Choloepus hoffmanni	25.41	1.00e-17	83.20
IUUC-Dre-028253	Danio rerio	24.36	2.00e-17	83.60
IUUC-Dno-029616	Dasypus novemcinctus	24.80	1.00e-20	93.20
IUUC-Dor-030744	Dipodomys ordii	20.95	8.00e-13	68.20
IUUC-Ete-032434	Echinops telfairi	24.60	2.00e-21	96.30
IUUC-Eca-034410	Equus caballus	23.72	8.00e-20	90.90
IUUC-Eeu-034954	Erinaceus europaeus	22.65	2.00e-20	92.80
IUUC-Fca-035410	Felis catus	25.37	1.00e-20	93.60
IUUC-Fal-037583	Ficedula albicollis	21.37	1.00e-14	74.70
IUUC-Gmo-039353	Gadus morhua	20.90	2.00e-18	87.00
IUUC-Gga-041124	Gallus gallus	23.59	4.00e-20	92.80
IUUC-Gac-042350	Gasterosteus aculeatus	26.65	1.00e-19	90.10
IUUC-Ggo-045080	Gorilla gorilla	22.76	3.00e-18	85.50
IUUC-Hsa-046580	Homo sapiens	22.51	2.00e-17	82.80
IUUC-Itr-048145	Ictidomys tridecemlineatus	25.21	2.00e-22	99.00
IUUC-Lch-049464	Latimeria chalumnae	24.58	3.00e-25	108.00
IUUC-Loc-052707	Lepisosteus oculatus	26.94	4.00e-21	95.90
IUUC-Laf-054552	Loxodonta africana	21.45	3.00e-15	75.90
IUUC-Mcc-055349	Macaca mulatta	23.27	6.00e-20	90.90
IUUC-Meu-056674	Macropus eugenii	24.62	2.00e-21	96.30
IUUC-Mga-059589	Meleagris gallopavo	22.68	2.00e-14	72.40
IUUC-Mmr-061225	Microcebus murinus	24.43	1.00e-19	90.10
IUUC-Mdo-062597	Monodelphis domestica	23.55	5.00e-19	88.20
IUUC-Mmu-063099	Mus musculus	23.86	5.00e-21	94.70
IUUC-Mpu-066679	Mustela putorius furo	20.72	3.00e-16	79.70
IUUC-Mlu-067034	Myotis lucifugus	24.29	2.00e-20	93.20
IUUC-Nle-069855	Nomascus leucogenys	23.74	1.00e-20	93.20
IUUC-Opr-070954	Ochotona princeps	24.18	7.00e-22	97.40
IUUC-Ont-071586	Oreochromis niloticus	21.47	6.00e-20	92.00
IUUC-Ocu-074667	Oryctolagus cuniculus	21.16	5.00e-15	75.50
IUUC-Ola-086481	Oryzias latipes	20.45	3.00e-16	79.70
IUUC-Oga-087909	Otolemur garnettii	24.87	6.00e-24	104.00
IUUC-Oar-089619	Ovis aries	24.86	8.00e-22	97.40
IUUC-Ptr-090712	Pan troglodytes	22.67	8.00e-18	84.00
IUUC-Pan-092806	Papio anubis	23.27	1.00e-19	90.10
IUUC-Psi-093414	Pelodiscus sinensis	21.96	9.00e-17	80.50
IUUC-Pfo-096848	Poecilia formosa	24.35	3.00e-20	92.40
IUUC-Pab-098353	Pongo abelii	22.56	3.00e-18	85.50
IUUC-Pca-100183	Procavia capensis	24.79	9.00e-22	97.10
IUUC-Pva-102140	Pteropus vampyrus	23.99	7.00e-22	97.40
IUUC-Rno-105886	Rattus norvegicus	24.40	6.00e-21	94.40
IUUC-Sha-107458	Sarcophilus harrisii	23.21	1.00e-18	86.70
IUUC-Sar-113181	Sorex araneus	28.37	1.00e-12	67.80
IUUC-Ssc-116231	Sus scrofa	23.38	6.00e-21	94.40
IUUC-Tgu-117368	Taeniopygia guttata	22.62	6.00e-16	78.60
IUUC-Tru-118728	Takifugu rubripes	22.28	2.00e-18	87.00
IUUC-Tsy-119053	Tarsius syrichta	21.80	4.00e-15	75.90
IUUC-Tni-120290	Tetraodon nigroviridis	22.36	3.00e-17	82.00
IUUC-Tbe-128111	Tupaia belangeri	25.14	2.00e-22	99.00
IUUC-Ttr-128584	Tursiops truncatus	24.57	5.00e-21	94.70
IUUC-Vpa-130619	Vicugna pacos	28.37	8.00e-13	68.20
IUUC-Xtr-132137	Xenopus tropicalis	20.76	9.00e-11	60.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence