iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067978

Ensembl Protein ID

ENSMLUP00000016088.2

UniProt Accession

G1PXC2; G1PXC2_MYOLU

Genbank Protein ID

ENSMLUP00000016088

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02006287

Gene Name

PPARG

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000017638.2	ENSMLUT00000017643.2	ENSMLUP00000016088.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	97.03	0.00e+00	1022.00	IUUC-Hsa-046916

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MGETLGDSLI DPESDSFAGT LSASTSQEIT MVDTEMPFWP TNFGISSVDL SVMDDHSHAF 60
DIKPFTTVDF SSISTPHYED IPFARADPMV ADYKYDLKLQ DYQNAIKVEP ASPPYYSEKA 120

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Nucleotide Sequence
(Fasta)

TTTCTTTTAA CGGATTGGTC TTTTGCAAGA AATAGACAAA ATATCAGTGT GAATCACACC 60
AATTCCTATT CCATGCTGTT ATGGGTGAAA CTCTGGGAGA TTCTCTTATT GACCCAGAAA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003077--1Cnucl_rcpt_G
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR022590--PPARgamma_N
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF12577--PPARgamma_N
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01291--PROXISOMPAGR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0090575--C:RNA polymerase II transcription factor complex
GO:0008144--F:drug binding
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0043565--F:sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0048469--P:cell maturation
GO:0032869--P:cellular response to insulin stimulus
GO:0042593--P:glucose homeostasis
GO:0042953--P:lipoprotein transport
GO:0045713--P:low-density lipoprotein particle receptor biosynthetic process
GO:0010742--P:macrophage derived foam cell differentiation
GO:0030224--P:monocyte differentiation
GO:0010887--P:negative regulation of cholesterol storage
GO:0060336--P:negative regulation of interferon-gamma-mediated signaling pathway
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0048662--P:negative regulation of smooth muscle cell proliferation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0035357--P:peroxisome proliferator activated receptor signaling pathway
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0008217--P:regulation of blood pressure
GO:0055098--P:response to low-density lipoprotein particle
GO:0032526--P:response to retinoic acid
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001214	Ailuropoda melanoleuca	95.45	0.00e+00	968.00
IUUC-Apl-003330	Anas platyrhynchos	63.52	1.00e-151	529.00
IUUC-Aca-005129	Anolis carolinensis	88.59	0.00e+00	881.00
IUUC-Ame-010818	Astyanax mexicanus	65.78	0.00e+00	645.00
IUUC-Bta-013226	Bos taurus	96.63	0.00e+00	987.00
IUUC-Cja-019236	Callithrix jacchus	97.23	0.00e+00	991.00
IUUC-Cfa-020281	Canis familiaris	98.42	0.00e+00	1007.00
IUUC-Cpo-021587	Cavia porcellus	96.03	0.00e+00	933.00
IUUC-Csa-023400	Chlorocebus sabaeus	98.11	0.00e+00	944.00
IUUC-Cho-024593	Choloepus hoffmanni	85.94	0.00e+00	856.00
IUUC-Dre-028176	Danio rerio	60.82	6.00e-154	536.00
IUUC-Dno-029063	Dasypus novemcinctus	93.27	0.00e+00	947.00
IUUC-Dor-030581	Dipodomys ordii	65.44	9.00e-153	533.00
IUUC-Dme-031794	Drosophila melanogaster	34.89	1.00e-55	212.00
IUUC-Ete-032520	Echinops telfairi	94.06	0.00e+00	950.00
IUUC-Eca-033712	Equus caballus	64.91	9.00e-152	530.00
IUUC-Fca-035935	Felis catus	98.42	0.00e+00	1004.00
IUUC-Fal-037524	Ficedula albicollis	92.42	0.00e+00	887.00
IUUC-Gmo-039240	Gadus morhua	64.00	3.00e-144	504.00
IUUC-Gga-041223	Gallus gallus	92.84	0.00e+00	891.00
IUUC-Gac-042156	Gasterosteus aculeatus	62.33	0.00e+00	641.00
IUUC-Ggo-045265	Gorilla gorilla	97.03	0.00e+00	994.00
IUUC-Hsa-046916	Homo sapiens	97.03	0.00e+00	993.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	65.17	2.00e-151	528.00
IUUC-Lch-049759	Latimeria chalumnae	80.30	0.00e+00	679.00
IUUC-Loc-051870	Lepisosteus oculatus	73.97	0.00e+00	749.00
IUUC-Laf-054483	Loxodonta africana	96.04	0.00e+00	978.00
IUUC-Mcc-054841	Macaca mulatta	64.91	6.00e-149	520.00
IUUC-Meu-056587	Macropus eugenii	93.80	0.00e+00	915.00
IUUC-Mga-059530	Meleagris gallopavo	92.84	0.00e+00	891.00
IUUC-Mmr-060576	Microcebus murinus	95.84	0.00e+00	981.00
IUUC-Mdo-061854	Monodelphis domestica	97.47	0.00e+00	934.00
IUUC-Mmu-063724	Mus musculus	95.64	0.00e+00	981.00
IUUC-Mpu-066888	Mustela putorius furo	98.95	0.00e+00	983.00
IUUC-Nle-070069	Nomascus leucogenys	97.43	0.00e+00	996.00
IUUC-Opr-070630	Ochotona princeps	92.91	0.00e+00	786.00
IUUC-Ont-071399	Oreochromis niloticus	59.33	6.00e-180	624.00
IUUC-Oan-073501	Ornithorhynchus anatinus	63.85	1.00e-143	503.00
IUUC-Ocu-074862	Oryctolagus cuniculus	97.06	0.00e+00	941.00
IUUC-Ola-087266	Oryzias latipes	56.42	1.00e-159	556.00
IUUC-Oga-089143	Otolemur garnettii	96.24	0.00e+00	986.00
IUUC-Oar-089725	Ovis aries	96.63	0.00e+00	986.00
IUUC-Ptr-091580	Pan troglodytes	97.23	0.00e+00	994.00
IUUC-Pan-092006	Papio anubis	64.91	5.00e-149	520.00
IUUC-Psi-093041	Pelodiscus sinensis	90.99	0.00e+00	870.00
IUUC-Ppa-095660	Physcomitrella patens	27.85	1.60e-01	32.30
IUUC-Pfo-097438	Poecilia formosa	58.99	9.00e-178	616.00
IUUC-Pab-098333	Pongo abelii	97.48	0.00e+00	937.00
IUUC-Pca-100861	Procavia capensis	97.06	0.00e+00	937.00
IUUC-Pva-102186	Pteropus vampyrus	88.91	0.00e+00	884.00
IUUC-Rno-105583	Rattus norvegicus	95.64	0.00e+00	980.00
IUUC-Sha-107484	Sarcophilus harrisii	95.10	0.00e+00	936.00
IUUC-Sar-112996	Sorex araneus	85.04	0.00e+00	647.00
IUUC-Ssc-115945	Sus scrofa	97.43	0.00e+00	993.00
IUUC-Tgu-116778	Taeniopygia guttata	63.41	2.00e-151	528.00
IUUC-Tru-118436	Takifugu rubripes	60.30	3.00e-145	508.00
IUUC-Tsy-119098	Tarsius syrichta	87.72	0.00e+00	865.00
IUUC-Tni-120902	Tetraodon nigroviridis	61.30	9.00e-174	603.00
IUUC-Tbe-127225	Tupaia belangeri	75.64	0.00e+00	717.00
IUUC-Ttr-129292	Tursiops truncatus	97.62	0.00e+00	996.00
IUUC-Vpa-130378	Vicugna pacos	92.51	0.00e+00	796.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence