iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090453

Ensembl Protein ID

ENSOARP00000020869.1

UniProt Accession

W5QDS1; W5QDS1_SHEEP

Genbank Protein ID

ENSOARP00000020869

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01084354

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000019427.1	ENSOART00000021157.1	ENSOARP00000020869.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	94.44	0.00e+00	887.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MEMVDTESPI GPLSPLEADD LESPLSADFL QEMGTIQEIS QSIGEDSSGS FSFTEYQYLG 60
SGPGSDGSVI TDTLSPASSP SSASYPAVPG SAEESSSIAL NIECRICGDK ASGYHYGVHA 120

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Nucleotide Sequence
(Fasta)

GGCGGCGGAC GGGGAGGGGC CGGGTGGCGC ATGCGCGGGG CCCCAGGGCG CGGGGTGAGG 60
GCGCTCGCTG CTGGCTAGTG CTGGGGATCC CGGGGCCCAG GGGGCCTCCC CTTGGTCGGC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0070166--P:enamel mineralization
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

KEGG

oas:443457

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	93.43	0.00e+00	895.00
IUUC-Apl-003330	Anas platyrhynchos	87.95	0.00e+00	822.00
IUUC-Aca-004598	Anolis carolinensis	85.53	0.00e+00	822.00
IUUC-Acl-008339	Aspergillus clavatus	45.45	1.40e-01	29.60
IUUC-Ame-011508	Astyanax mexicanus	74.47	0.00e+00	691.00
IUUC-Bta-012621	Bos taurus	98.94	0.00e+00	927.00
IUUC-Cja-019688	Callithrix jacchus	93.80	0.00e+00	884.00
IUUC-Cfa-020859	Canis familiaris	94.87	0.00e+00	902.00
IUUC-Cpo-021607	Cavia porcellus	88.03	0.00e+00	827.00
IUUC-Csa-023313	Chlorocebus sabaeus	93.80	0.00e+00	878.00
IUUC-Cho-024741	Choloepus hoffmanni	83.33	0.00e+00	749.00
IUUC-Cgl-026615	Colletotrichum gloeosporioides	34.15	1.10e+00	25.80
IUUC-Dre-027446	Danio rerio	71.91	0.00e+00	665.00
IUUC-Dno-029173	Dasypus novemcinctus	90.85	0.00e+00	831.00
IUUC-Dor-030581	Dipodomys ordii	91.01	0.00e+00	808.00
IUUC-Ete-032330	Echinops telfairi	91.24	0.00e+00	861.00
IUUC-Eca-033712	Equus caballus	94.66	0.00e+00	880.00
IUUC-Fca-036555	Felis catus	94.89	0.00e+00	900.00
IUUC-Fal-036677	Ficedula albicollis	88.03	0.00e+00	821.00
IUUC-Gmo-039240	Gadus morhua	81.55	0.00e+00	642.00
IUUC-Gga-040473	Gallus gallus	88.68	0.00e+00	825.00
IUUC-Gac-041872	Gasterosteus aculeatus	72.09	0.00e+00	683.00
IUUC-Ggo-045226	Gorilla gorilla	94.44	0.00e+00	885.00
IUUC-Hsa-046893	Homo sapiens	94.44	0.00e+00	885.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	91.88	0.00e+00	862.00
IUUC-Lch-050116	Latimeria chalumnae	79.49	0.00e+00	741.00
IUUC-Loc-052131	Lepisosteus oculatus	83.85	0.00e+00	667.00
IUUC-Laf-054323	Loxodonta africana	94.23	0.00e+00	887.00
IUUC-Mcc-054841	Macaca mulatta	94.44	0.00e+00	882.00
IUUC-Meu-056833	Macropus eugenii	82.26	0.00e+00	748.00
IUUC-Mga-059995	Meleagris gallopavo	79.03	0.00e+00	723.00
IUUC-Mdo-061954	Monodelphis domestica	89.03	0.00e+00	771.00
IUUC-Mmu-064295	Mus musculus	90.81	0.00e+00	824.00
IUUC-Mpu-066216	Mustela putorius furo	94.87	0.00e+00	899.00
IUUC-Nle-069970	Nomascus leucogenys	94.23	0.00e+00	882.00
IUUC-Ont-071594	Oreochromis niloticus	73.15	0.00e+00	673.00
IUUC-Oan-073501	Ornithorhynchus anatinus	92.18	0.00e+00	743.00
IUUC-Ocu-074634	Oryctolagus cuniculus	83.10	0.00e+00	818.00
IUUC-Oni-082926	Oryza nivara	27.45	2.10e-02	30.00
IUUC-Ola-086585	Oryzias latipes	79.63	0.00e+00	638.00
IUUC-Oga-088738	Otolemur garnettii	94.89	0.00e+00	884.00
IUUC-Ptr-091518	Pan troglodytes	94.23	0.00e+00	878.00
IUUC-Pan-092006	Papio anubis	94.23	0.00e+00	878.00
IUUC-Psi-093352	Pelodiscus sinensis	87.08	0.00e+00	819.00
IUUC-Pfo-096060	Poecilia formosa	72.73	0.00e+00	673.00
IUUC-Pab-098602	Pongo abelii	87.97	0.00e+00	785.00
IUUC-Pva-102175	Pteropus vampyrus	89.53	0.00e+00	838.00
IUUC-Rno-105283	Rattus norvegicus	91.45	0.00e+00	825.00
IUUC-Sce-106436	Saccharomyces cerevisiae	29.03	1.00e-02	31.60
IUUC-Sha-106560	Sarcophilus harrisii	91.68	0.00e+00	844.00
IUUC-Smo-109075	Selaginella moellendorffii	28.00	6.10e-01	27.30
IUUC-Ssc-115266	Sus scrofa	94.66	0.00e+00	904.00
IUUC-Tgu-116778	Taeniopygia guttata	87.66	0.00e+00	821.00
IUUC-Tru-118436	Takifugu rubripes	71.88	0.00e+00	673.00
IUUC-Tsy-119642	Tarsius syrichta	81.20	0.00e+00	731.00
IUUC-Tni-119859	Tetraodon nigroviridis	72.30	0.00e+00	672.00
IUUC-Tvi-122624	Trichoderma virens	31.48	2.00e-01	28.50
IUUC-Tbe-127464	Tupaia belangeri	92.52	0.00e+00	882.00
IUUC-Ttr-129307	Tursiops truncatus	92.75	0.00e+00	852.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence