iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074132

UUCD1 version

UUC-OrC-00755

Ensembl Protein ID

ENSOCUP00000013255.3

UniProt Accession

G1T9F0; G1T9F0_RABIT

Protein Name

Tripartite motif-containing protein 72

Gene Name

TRIM72

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000015430.3	ENSOCUT00000015428.3	ENSOCUP00000013255.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	6.50e-07	29.4	10	76
E3 activity/RING/RING	6.70e-07	29.8	14	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwl...asggk....tcPvtrqplteedlvPnltlrrliq 66
           +e+ Cp+ l+l+  Pv++++G+++ r+++ +     a         cP +++p++++ l  nl l rl++
   Q: 10   QELSCPLCLQLFDAPVTAECGHSFCRACLSRVAgepA---AdgtvNCPCCQAPTRPQALSTNLQLARLVE 76
           7899***************************765553...14447*****************99988765 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl+ f+  p++  CgH f++ Cl ++      + ++ +CP C+
   Q: 14   CPLCLQLFDA-PVTAECGHSFCRACLSRV-AGEPAADGTVNCPCCQ 57
           ********99.999***************.5555899999*****7 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MSAAPGLLHQ ELSCPLCLQL FDAPVTAECG HSFCRACLSR VAGEPAADGT VNCPCCQAPT 60
RPQALSTNLQ LARLVEGLAQ VPQGHCEEHL DPLSIYCEQD RVLVCGVCAS LGSHRGHRLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACGCTAAA TATAGTCCCT GGGGCCCTGG CTTGGCCGGG AGGATCGGCC CGCTGTTTGC 60
CAGGCGCCAT CACCCGCTGG TGTCCACTGC CAGCTGCCCC GTGAGGCTCC TGTGCTCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING

Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0042383--C:sarcolemma
GO:0001786--F:phosphatidylserine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007517--P:muscle organ development
GO:0003012--P:muscle system process
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0043569--P:negative regulation of insulin-like growth factor receptor signaling pathway
GO:0010832--P:negative regulation of myotube differentiation
GO:0001778--P:plasma membrane repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002377	Ailuropoda melanoleuca	60.37	3.00e-130	458.00
IUUC-Aca-004755	Anolis carolinensis	55.68	4.00e-134	471.00
IUUC-Bta-013476	Bos taurus	71.98	8.00e-149	520.00
IUUC-Cel-018370	Caenorhabditis elegans	37.63	3.00e-08	52.40
IUUC-Cja-018969	Callithrix jacchus	80.81	5.00e-151	527.00
IUUC-Cfa-020155	Canis familiaris	77.04	0.00e+00	656.00
IUUC-Cpo-021646	Cavia porcellus	75.21	0.00e+00	640.00
IUUC-Csa-023855	Chlorocebus sabaeus	93.69	3.00e-109	387.00
IUUC-Dno-029142	Dasypus novemcinctus	76.39	5.00e-178	617.00
IUUC-Dor-030394	Dipodomys ordii	88.37	3.00e-63	235.00
IUUC-Ete-032801	Echinops telfairi	80.95	3.00e-41	162.00
IUUC-Eca-034378	Equus caballus	93.94	0.00e+00	665.00
IUUC-Eeu-034526	Erinaceus europaeus	86.15	3.00e-166	577.00
IUUC-Fca-036440	Felis catus	93.65	0.00e+00	662.00
IUUC-Ggo-045086	Gorilla gorilla	95.04	0.00e+00	638.00
IUUC-Hsa-046533	Homo sapiens	95.04	0.00e+00	637.00
IUUC-Itr-048959	Ictidomys tridecemlineatus	94.21	0.00e+00	663.00
IUUC-Laf-054479	Loxodonta africana	93.94	0.00e+00	660.00
IUUC-Mcc-055814	Macaca mulatta	92.88	5.00e-175	607.00
IUUC-Meu-056767	Macropus eugenii	63.54	4.00e-157	547.00
IUUC-Mmr-061616	Microcebus murinus	78.83	0.00e+00	694.00
IUUC-Mdo-062252	Monodelphis domestica	64.74	1.00e-157	549.00
IUUC-Mmu-063094	Mus musculus	91.58	0.00e+00	631.00
IUUC-Mpu-065885	Mustela putorius furo	63.31	3.00e-144	504.00
IUUC-Mlu-068150	Myotis lucifugus	65.16	2.00e-85	308.00
IUUC-Nle-069476	Nomascus leucogenys	95.05	0.00e+00	632.00
IUUC-Opr-070871	Ochotona princeps	93.73	4.00e-146	511.00
IUUC-Oan-072738	Ornithorhynchus anatinus	64.96	2.00e-159	555.00
IUUC-Olu-087666	Ostreococcus lucimarinus	39.19	2.00e-10	60.80
IUUC-Oga-088268	Otolemur garnettii	50.10	5.00e-96	344.00
IUUC-Oar-089555	Ovis aries	70.72	2.00e-164	571.00
IUUC-Ptr-090792	Pan troglodytes	95.04	0.00e+00	637.00
IUUC-Pan-092897	Papio anubis	95.32	0.00e+00	637.00
IUUC-Pab-098716	Pongo abelii	95.32	0.00e+00	638.00
IUUC-Pca-100618	Procavia capensis	83.47	1.00e-162	566.00
IUUC-Pva-102430	Pteropus vampyrus	81.54	1.00e-157	549.00
IUUC-Rno-105665	Rattus norvegicus	91.03	0.00e+00	650.00
IUUC-Sha-106854	Sarcophilus harrisii	54.56	3.00e-128	451.00
IUUC-Sar-113028	Sorex araneus	89.19	1.00e-104	372.00
IUUC-Ssc-116124	Sus scrofa	92.56	1.00e-180	625.00
IUUC-Tbe-127273	Tupaia belangeri	93.85	1.00e-68	253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence