iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037120

Ensembl Protein ID

ENSFALP00000004954.1

UniProt Accession

U3JQA0; U3JQA0_FICAL

Genbank Protein ID

ENSFALP00000004954

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AGTO01001119

Gene Name

ING4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000004756.1	ENSFALT00000004978.1	ENSFALP00000004954.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.00e-10	39.1	197	244

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+aC++l+   ++p+ + w+Cp+C++
   Q: 197  TYC-LCHQVSYGE--MIGCDNpdCSiEWFHFACVGLT---TKPRGK-WFCPRCSQ 244
           69*.*******99..********999***********...899996.******97 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

SAQSVYCPLY VKCIENLPFE LQRNFQLMRD LDQRTEDLKS EIDKLATEYI SNARTLSSEE 60
KLGLLKQIQE AYGKCKEFGD DKVQLAMQTY EMVDKHIRRL DTDLARFEAD LKEKQIESSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTGCCCAAA GTGTCTACTG TCCCCTGTAT GTTAAATGAA TGCATTAAAC AGACTCACTT 60
TTCAGAGTGT TAGTATTTGA TCAACTTAAT TTTTACATCC TTGTATAGAA ATAACGAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0000123--C:histone acetyltransferase complex
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0007050--P:cell cycle arrest
GO:0006978--P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0006260--P:DNA replication
GO:0043966--P:histone H3 acetylation
GO:0043983--P:histone H4-K12 acetylation
GO:0043981--P:histone H4-K5 acetylation
GO:0043982--P:histone H4-K8 acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0045926--P:negative regulation of growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001338	Ailuropoda melanoleuca	91.94	1.00e-116	411.00
IUUC-Atr-002906	Amborella trichopoda	33.47	2.00e-32	131.00
IUUC-Apl-004097	Anas platyrhynchos	95.97	3.00e-120	424.00
IUUC-Aca-004593	Anolis carolinensis	96.37	2.00e-121	427.00
IUUC-Ago-007842	Ashbya gossypii	30.23	3.90e+00	26.60
IUUC-Ame-011133	Astyanax mexicanus	78.00	2.00e-111	394.00
IUUC-Bta-012699	Bos taurus	90.73	2.00e-116	410.00
IUUC-Bdi-014504	Brachypodium distachyon	35.80	8.00e-38	149.00
IUUC-Bol-015245	Brassica oleracea	32.64	3.00e-30	124.00
IUUC-Bra-017027	Brassica rapa	33.05	8.00e-31	126.00
IUUC-Cja-019988	Callithrix jacchus	93.15	7.00e-112	395.00
IUUC-Cfa-021282	Canis familiaris	92.34	8.00e-111	392.00
IUUC-Cpo-022011	Cavia porcellus	92.34	3.00e-120	423.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	34.29	2.00e-28	119.00
IUUC-Csa-023203	Chlorocebus sabaeus	93.15	7.00e-112	395.00
IUUC-Cin-025479	Ciona intestinalis	58.65	1.00e-74	272.00
IUUC-Csv-026288	Ciona savignyi	52.63	3.00e-70	258.00
IUUC-Dre-028264	Danio rerio	77.60	7.00e-110	389.00
IUUC-Dno-029766	Dasypus novemcinctus	96.20	1.00e-110	391.00
IUUC-Dor-031136	Dipodomys ordii	91.46	4.00e-91	327.00
IUUC-Eca-033565	Equus caballus	92.74	3.00e-120	423.00
IUUC-Eeu-034948	Erinaceus europaeus	78.90	4.00e-95	340.00
IUUC-Fca-036368	Felis catus	92.74	2.00e-111	394.00
IUUC-Gmo-038982	Gadus morhua	78.71	4.00e-110	390.00
IUUC-Gga-040771	Gallus gallus	96.37	2.00e-121	427.00
IUUC-Gac-042184	Gasterosteus aculeatus	78.86	4.00e-108	383.00
IUUC-Ggo-045559	Gorilla gorilla	93.15	7.00e-112	395.00
IUUC-Hsa-046852	Homo sapiens	93.15	7.00e-112	395.00
IUUC-Hvu-047046	Hordeum vulgare	36.48	7.00e-37	147.00
IUUC-Itr-047978	Ictidomys tridecemlineatus	92.34	6.00e-120	422.00
IUUC-Kpa-049229	Komagataella pastoris	59.18	2.00e-16	79.00
IUUC-Laf-054057	Loxodonta africana	92.74	2.00e-111	394.00
IUUC-Mcc-055212	Macaca mulatta	87.20	8.00e-106	375.00
IUUC-Meu-056511	Macropus eugenii	91.49	4.00e-111	393.00
IUUC-Mtr-058288	Medicago truncatula	31.60	5.00e-31	127.00
IUUC-Mga-059967	Meleagris gallopavo	100.00	6.00e-120	422.00
IUUC-Mmr-060843	Microcebus murinus	90.73	1.00e-116	411.00
IUUC-Mdo-062357	Monodelphis domestica	91.94	1.00e-119	421.00
IUUC-Mmu-064093	Mus musculus	92.34	3.00e-120	423.00
IUUC-Mpu-066923	Mustela putorius furo	81.05	2.00e-88	318.00
IUUC-Mlu-067754	Myotis lucifugus	85.66	2.00e-108	384.00
IUUC-Nle-069062	Nomascus leucogenys	93.15	7.00e-112	395.00
IUUC-Opr-070207	Ochotona princeps	89.83	8.00e-109	385.00
IUUC-Ont-072446	Oreochromis niloticus	79.12	9.00e-109	385.00
IUUC-Ocu-074235	Oryctolagus cuniculus	92.34	8.00e-111	392.00
IUUC-Ogl-077118	Oryza glaberrima	33.61	4.00e-35	141.00
IUUC-Ola-086429	Oryzias latipes	74.30	1.00e-99	355.00
IUUC-Olu-087851	Ostreococcus lucimarinus	34.57	9.00e-20	89.70
IUUC-Oga-089123	Otolemur garnettii	92.74	2.00e-111	394.00
IUUC-Oar-089524	Ovis aries	90.73	2.00e-116	410.00
IUUC-Ptr-090908	Pan troglodytes	92.74	2.00e-111	394.00
IUUC-Pan-092837	Papio anubis	92.34	3.00e-117	413.00
IUUC-Psi-093828	Pelodiscus sinensis	99.57	4.00e-117	413.00
IUUC-Ppa-096009	Physcomitrella patens	33.20	9.00e-31	126.00
IUUC-Pfo-096617	Poecilia formosa	78.71	8.00e-109	385.00
IUUC-Pab-097978	Pongo abelii	96.19	6.00e-108	382.00
IUUC-Pop-099415	Populus trichocarpa	73.68	2.00e-26	111.00
IUUC-Pca-100475	Procavia capensis	60.48	4.00e-75	273.00
IUUC-Pva-102325	Pteropus vampyrus	92.74	3.00e-120	423.00
IUUC-Rno-105178	Rattus norvegicus	90.73	2.00e-125	441.00
IUUC-Sha-106773	Sarcophilus harrisii	91.94	1.00e-119	422.00
IUUC-Sly-111750	Solanum lycopersicum	34.98	3.00e-35	141.00
IUUC-Stu-112250	Solanum tuberosum	34.98	3.00e-35	141.00
IUUC-Sre-115124	Sporisorium reilianum	51.85	1.00e-22	101.00
IUUC-Ssc-115797	Sus scrofa	93.22	6.00e-103	366.00
IUUC-Tgu-117270	Taeniopygia guttata	96.37	2.00e-121	427.00
IUUC-Tru-118253	Takifugu rubripes	78.00	4.00e-109	386.00
IUUC-Tbe-127558	Tupaia belangeri	91.94	1.00e-116	411.00
IUUC-Ttr-128300	Tursiops truncatus	97.27	1.00e-63	235.00
IUUC-Uma-129581	Ustilago maydis	57.63	5.00e-21	96.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence