iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073699

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPN01189974

Gene Name

KLHL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000014478.3	ENSOANT00000022825.3	ENSOANP00000022821.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/BCR/BTB_3-box	61.66	2.00e-178	622.00	IUUC-Dme-032172
E3 adaptor/Cullin RING/BCR/BTB_3-box	94.69	0.00e+00	961.00	IUUC-Hsa-046265

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

GEMSESRAKR VRIKEVDGWT LKMLIDYVYT AEIHVTEENV QVLLPAAGLL QLQDVKKTCC 60
DFLESQLHPI NCLGIRAFAD MHACTDLLNK ANTYAEQHFS DVVLSEEFLN LGIEQVCGLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGACTAACC CATGGCTACA AAGAATTAAC TGTACATTTG TATCGTAGGA GAGATGAGTG 60
AGAGCCGGGC AAAGAGAGTT CGAATAAAGG AGGTGGATGG CTGGACCCTC AAGATGCTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0003779--F:actin binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002378	Ailuropoda melanoleuca	94.49	0.00e+00	961.00
IUUC-Apl-003260	Anas platyrhynchos	91.73	0.00e+00	937.00
IUUC-Aca-005143	Anolis carolinensis	89.37	0.00e+00	945.00
IUUC-Ame-010670	Astyanax mexicanus	75.20	0.00e+00	768.00
IUUC-Bta-013354	Bos taurus	79.02	0.00e+00	833.00
IUUC-Cel-018136	Caenorhabditis elegans	41.73	1.00e-111	396.00
IUUC-Cja-018942	Callithrix jacchus	94.49	0.00e+00	961.00
IUUC-Cfa-020886	Canis familiaris	94.69	0.00e+00	963.00
IUUC-Cpo-022543	Cavia porcellus	94.69	0.00e+00	963.00
IUUC-Csa-023088	Chlorocebus sabaeus	94.49	0.00e+00	961.00
IUUC-Csv-026032	Ciona savignyi	60.76	0.00e+00	646.00
IUUC-Cgl-026620	Colletotrichum gloeosporioides	29.49	3.00e-24	105.00
IUUC-Dre-028082	Danio rerio	83.86	0.00e+00	861.00
IUUC-Dno-029873	Dasypus novemcinctus	92.58	0.00e+00	941.00
IUUC-Dor-030460	Dipodomys ordii	72.83	0.00e+00	665.00
IUUC-Dme-032172	Drosophila melanogaster	61.66	5.00e-172	598.00
IUUC-Ete-033064	Echinops telfairi	64.30	1.00e-161	562.00
IUUC-Eca-033798	Equus caballus	94.09	0.00e+00	959.00
IUUC-Eeu-034824	Erinaceus europaeus	93.80	0.00e+00	875.00
IUUC-Fca-036455	Felis catus	94.69	0.00e+00	963.00
IUUC-Fal-037293	Ficedula albicollis	91.34	0.00e+00	936.00
IUUC-Gmo-038811	Gadus morhua	78.94	0.00e+00	764.00
IUUC-Gga-040805	Gallus gallus	91.14	0.00e+00	934.00
IUUC-Gac-041979	Gasterosteus aculeatus	81.69	0.00e+00	768.00
IUUC-Ggo-044620	Gorilla gorilla	90.60	0.00e+00	904.00
IUUC-Hsa-046265	Homo sapiens	94.69	0.00e+00	962.00
IUUC-Itr-048605	Ictidomys tridecemlineatus	79.13	0.00e+00	835.00
IUUC-Lch-049939	Latimeria chalumnae	85.43	0.00e+00	853.00
IUUC-Loc-052780	Lepisosteus oculatus	87.99	0.00e+00	900.00
IUUC-Laf-053800	Loxodonta africana	94.49	0.00e+00	962.00
IUUC-Mcc-055732	Macaca mulatta	93.29	0.00e+00	947.00
IUUC-Meu-056011	Macropus eugenii	95.47	0.00e+00	971.00
IUUC-Mga-059994	Meleagris gallopavo	79.42	0.00e+00	722.00
IUUC-Mmr-061067	Microcebus murinus	92.93	0.00e+00	944.00
IUUC-Mdo-062977	Monodelphis domestica	95.67	0.00e+00	968.00
IUUC-Mmu-064035	Mus musculus	94.20	0.00e+00	945.00
IUUC-Mpu-066726	Mustela putorius furo	94.49	0.00e+00	961.00
IUUC-Mlu-067020	Myotis lucifugus	94.49	0.00e+00	962.00
IUUC-Nle-069456	Nomascus leucogenys	94.69	0.00e+00	963.00
IUUC-Opr-071130	Ochotona princeps	84.25	0.00e+00	824.00
IUUC-Ont-072219	Oreochromis niloticus	83.27	0.00e+00	817.00
IUUC-Ocu-074045	Oryctolagus cuniculus	94.49	0.00e+00	960.00
IUUC-Ola-086853	Oryzias latipes	74.02	0.00e+00	746.00
IUUC-Oga-088494	Otolemur garnettii	94.29	0.00e+00	960.00
IUUC-Oar-089645	Ovis aries	94.49	0.00e+00	961.00
IUUC-Ptr-091063	Pan troglodytes	94.69	0.00e+00	962.00
IUUC-Pan-091705	Papio anubis	79.33	0.00e+00	837.00
IUUC-Psi-093946	Pelodiscus sinensis	91.73	0.00e+00	951.00
IUUC-Pma-094177	Petromyzon marinus	75.93	0.00e+00	715.00
IUUC-Pfo-096817	Poecilia formosa	82.28	0.00e+00	831.00
IUUC-Pab-097768	Pongo abelii	94.49	0.00e+00	960.00
IUUC-Pca-100607	Procavia capensis	82.67	0.00e+00	715.00
IUUC-Pva-102218	Pteropus vampyrus	87.80	0.00e+00	876.00
IUUC-Rno-105250	Rattus norvegicus	94.49	0.00e+00	961.00
IUUC-Sha-106935	Sarcophilus harrisii	81.12	6.00e-180	622.00
IUUC-Sar-113249	Sorex araneus	93.99	0.00e+00	940.00
IUUC-Ssc-115423	Sus scrofa	94.69	0.00e+00	962.00
IUUC-Tgu-117050	Taeniopygia guttata	90.77	0.00e+00	925.00
IUUC-Tru-118239	Takifugu rubripes	81.73	0.00e+00	857.00
IUUC-Tsy-119377	Tarsius syrichta	79.53	0.00e+00	805.00
IUUC-Tni-120122	Tetraodon nigroviridis	80.40	0.00e+00	786.00
IUUC-Ttr-128574	Tursiops truncatus	93.08	3.00e-146	511.00
IUUC-Vpa-130707	Vicugna pacos	90.58	0.00e+00	847.00
IUUC-Xtr-132035	Xenopus tropicalis	88.61	0.00e+00	931.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence