iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132876

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like family member 21

Genbank Nucleotide ID

AAMC01027211

Gene Name

klhl21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000011114.2	ENSXETT00000024281.2	ENSXETP00000024281.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.00e-17	62.9	47	110
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	8.20e-08	31.5	145	175

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           D+++  gg+ f++h+ vLaa+S +F+a+f + l+es+  + ve++dv    ++ ll+F+Ytg+++
   Q: 47   DMTVSAGGQDFPCHRTVLAAASNYFRAMFAGRLRESH-VDQVELHDVTGPILSLLLDFCYTGRVT 110
           889999******************************9.*************************96 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Ncl+i +fA++y c  L+++  +fil h+
   Q: 145  VSNCLEIQDFAEAYACQGLAESTKRFILAHM 175
           69***************************97 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MDTPINTSPS SAGIPASEAS LPFYDASHAL HLLRGINELR AEQKFFDMTV SAGGQDFPCH 60
RTVLAAASNY FRAMFAGRLR ESHVDQVELH DVTGPILSLL LDFCYTGRVT VTLENVEPLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATACAC CCATCAACAC TTCCCCCAGT TCAGCGGGGA TTCCAGCATC TGAGGCATCC 60
CTGCCTTTCT ACGATGCCTC CCATGCTCTG CACTTGTTAC GGGGCATCAA TGAGCTCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001782	Ailuropoda melanoleuca	67.70	0.00e+00	734.00
IUUC-Apl-003189	Anas platyrhynchos	82.41	3.00e-147	514.00
IUUC-Ame-011774	Astyanax mexicanus	70.66	1.00e-151	528.00
IUUC-Bta-012367	Bos taurus	73.71	0.00e+00	893.00
IUUC-Cja-019501	Callithrix jacchus	67.44	0.00e+00	815.00
IUUC-Cfa-020550	Canis familiaris	72.21	0.00e+00	892.00
IUUC-Cpo-022072	Cavia porcellus	74.09	0.00e+00	878.00
IUUC-Csa-023364	Chlorocebus sabaeus	75.29	0.00e+00	815.00
IUUC-Cin-025253	Ciona intestinalis	44.28	1.00e-150	526.00
IUUC-Csv-025871	Ciona savignyi	45.68	3.00e-158	551.00
IUUC-Dre-028694	Danio rerio	75.22	0.00e+00	920.00
IUUC-Dno-029082	Dasypus novemcinctus	74.61	0.00e+00	786.00
IUUC-Dor-030680	Dipodomys ordii	72.05	0.00e+00	889.00
IUUC-Ete-032315	Echinops telfairi	73.68	0.00e+00	783.00
IUUC-Eca-033570	Equus caballus	79.60	6.00e-171	592.00
IUUC-Eeu-035067	Erinaceus europaeus	78.24	4.00e-123	435.00
IUUC-Fca-035663	Felis catus	73.86	5.00e-103	366.00
IUUC-Fal-037103	Ficedula albicollis	71.38	0.00e+00	802.00
IUUC-Gmo-039420	Gadus morhua	71.48	0.00e+00	897.00
IUUC-Gga-040161	Gallus gallus	70.84	0.00e+00	798.00
IUUC-Gac-041755	Gasterosteus aculeatus	76.20	0.00e+00	923.00
IUUC-Ggo-044899	Gorilla gorilla	72.88	0.00e+00	892.00
IUUC-Hsa-045834	Homo sapiens	74.26	0.00e+00	889.00
IUUC-Itr-048413	Ictidomys tridecemlineatus	72.55	0.00e+00	892.00
IUUC-Lch-050338	Latimeria chalumnae	77.61	0.00e+00	976.00
IUUC-Loc-051780	Lepisosteus oculatus	75.90	0.00e+00	934.00
IUUC-Laf-053725	Loxodonta africana	77.83	0.00e+00	670.00
IUUC-Mcc-055032	Macaca mulatta	73.29	0.00e+00	759.00
IUUC-Meu-056661	Macropus eugenii	83.42	0.00e+00	673.00
IUUC-Mga-059821	Meleagris gallopavo	80.53	3.00e-129	454.00
IUUC-Mdo-062095	Monodelphis domestica	72.62	0.00e+00	758.00
IUUC-Mmu-063138	Mus musculus	72.05	0.00e+00	890.00
IUUC-Mpu-066386	Mustela putorius furo	80.79	1.00e-160	558.00
IUUC-Mlu-067807	Myotis lucifugus	80.34	3.00e-172	597.00
IUUC-Nle-069181	Nomascus leucogenys	72.50	0.00e+00	876.00
IUUC-Opr-070658	Ochotona princeps	72.24	0.00e+00	904.00
IUUC-Ont-072209	Oreochromis niloticus	76.26	0.00e+00	914.00
IUUC-Oan-072861	Ornithorhynchus anatinus	85.05	2.00e-109	387.00
IUUC-Ocu-074631	Oryctolagus cuniculus	66.56	0.00e+00	780.00
IUUC-Ola-087553	Oryzias latipes	75.00	0.00e+00	898.00
IUUC-Oga-088782	Otolemur garnettii	73.04	0.00e+00	897.00
IUUC-Oar-089634	Ovis aries	73.37	0.00e+00	890.00
IUUC-Ptr-091259	Pan troglodytes	76.80	0.00e+00	691.00
IUUC-Pan-091734	Papio anubis	74.09	0.00e+00	893.00
IUUC-Psi-092979	Pelodiscus sinensis	72.08	0.00e+00	829.00
IUUC-Pma-094459	Petromyzon marinus	49.90	1.00e-124	439.00
IUUC-Pfo-097446	Poecilia formosa	75.13	0.00e+00	907.00
IUUC-Pab-098765	Pongo abelii	72.38	0.00e+00	893.00
IUUC-Pva-102730	Pteropus vampyrus	68.73	0.00e+00	840.00
IUUC-Rno-104972	Rattus norvegicus	74.27	0.00e+00	895.00
IUUC-Ssc-115869	Sus scrofa	73.25	0.00e+00	765.00
IUUC-Tgu-116562	Taeniopygia guttata	71.48	0.00e+00	825.00
IUUC-Tru-118490	Takifugu rubripes	73.81	0.00e+00	906.00
IUUC-Tni-119898	Tetraodon nigroviridis	70.36	0.00e+00	865.00
IUUC-Tme-127039	Tuber melanosporum	29.14	7.00e-13	69.70
IUUC-Ttr-128976	Tursiops truncatus	81.48	5.00e-123	434.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence