iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048226

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01032999

Gene Name

SH3RF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000002435.2	ENSSTOT00000002436.2	ENSSTOP00000002180.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.00e-08	32.7	12	53
UBD/SH3	1.40e-29	101.9	385	440

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+e ++   +vlpC+H+f++ Clq++     ++ ke rCP Cr
   Q: 12   CPVCFEKLDVTAKVLPCQHTFCKPCLQRI----FKAHKELRCPECR 53
           ********88899****************....99**********8 PP

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            + + +l++y+a   deL l+kG+ ++v+   ++  gWl+g +  +g+ G+fP+n+v 
   Q: 385  TNMFVALHSYSAHGPDELDLQKGEGIRVL--GKHQDGWLRGISLVTGRVGIFPNNYVI 440
           57899************************..77788********************96 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MDDLTLLDLL ECPVCFEKLD VTAKVLPCQH TFCKPCLQRI FKAHKELRCP ECRTLVFCSI 60
EALPANLLLV RLLDGVRSGQ SSGRVGSFRK LGMLTSQDGR RSRTSPRGLQ ASPFRPVPSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGGAATTC TGACGCTCTC AAGAGTCCCT GCTCTGCCAA CTTGGCTCAA GTGCCCCTAC 60
GATGTGGACC CTACTCCTTC AGGTCGGGGC TGGAGTTTTA AAATAAAATG GATGATTTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028511--SH3RF2
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010923--P:negative regulation of phosphatase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001594	Ailuropoda melanoleuca	84.77	0.00e+00	1116.00
IUUC-Apl-003443	Anas platyrhynchos	61.02	0.00e+00	642.00
IUUC-Aca-004632	Anolis carolinensis	56.95	8.00e-173	600.00
IUUC-Bta-013400	Bos taurus	86.32	0.00e+00	1072.00
IUUC-Cel-018180	Caenorhabditis elegans	28.66	4.00e-21	96.70
IUUC-Cja-019686	Callithrix jacchus	74.00	0.00e+00	921.00
IUUC-Cfa-020893	Canis familiaris	86.45	0.00e+00	1126.00
IUUC-Cpo-021638	Cavia porcellus	79.48	0.00e+00	1023.00
IUUC-Csa-023846	Chlorocebus sabaeus	86.15	0.00e+00	1138.00
IUUC-Cho-024609	Choloepus hoffmanni	82.89	5.00e-166	577.00
IUUC-Cin-025274	Ciona intestinalis	48.03	9.00e-62	229.00
IUUC-Csv-026136	Ciona savignyi	44.44	8.00e-61	227.00
IUUC-Cme-027278	Cyanidioschyzon merolae	42.11	4.00e-07	49.70
IUUC-Dno-028940	Dasypus novemcinctus	83.33	0.00e+00	1095.00
IUUC-Dor-030491	Dipodomys ordii	77.97	1.00e-136	479.00
IUUC-Ete-032513	Echinops telfairi	82.12	0.00e+00	1065.00
IUUC-Eca-034241	Equus caballus	87.53	0.00e+00	1174.00
IUUC-Eeu-034636	Erinaceus europaeus	78.25	0.00e+00	920.00
IUUC-Fca-035862	Felis catus	83.43	0.00e+00	1105.00
IUUC-Gga-040748	Gallus gallus	54.74	3.00e-156	545.00
IUUC-Gac-041420	Gasterosteus aculeatus	46.76	2.00e-80	293.00
IUUC-Ggo-045267	Gorilla gorilla	85.73	0.00e+00	1126.00
IUUC-Hsa-045761	Homo sapiens	85.46	0.00e+00	1118.00
IUUC-Lch-050498	Latimeria chalumnae	44.32	7.00e-124	437.00
IUUC-Laf-054061	Loxodonta africana	76.59	0.00e+00	814.00
IUUC-Mcc-054746	Macaca mulatta	85.30	0.00e+00	1095.00
IUUC-Meu-056390	Macropus eugenii	59.29	2.00e-88	320.00
IUUC-Mmr-061390	Microcebus murinus	82.01	0.00e+00	898.00
IUUC-Mdo-062951	Monodelphis domestica	71.88	0.00e+00	974.00
IUUC-Mmu-063840	Mus musculus	78.10	0.00e+00	1038.00
IUUC-Mpu-065840	Mustela putorius furo	84.79	0.00e+00	1143.00
IUUC-Mlu-067378	Myotis lucifugus	82.14	0.00e+00	1055.00
IUUC-Nle-069535	Nomascus leucogenys	82.69	0.00e+00	1043.00
IUUC-Opr-070739	Ochotona princeps	79.36	0.00e+00	1011.00
IUUC-Oan-073468	Ornithorhynchus anatinus	65.01	0.00e+00	789.00
IUUC-Ocu-074343	Oryctolagus cuniculus	81.04	0.00e+00	999.00
IUUC-Ola-086675	Oryzias latipes	42.94	5.00e-67	249.00
IUUC-Oga-088276	Otolemur garnettii	76.32	0.00e+00	988.00
IUUC-Oar-090315	Ovis aries	84.46	0.00e+00	1058.00
IUUC-Ptr-091119	Pan troglodytes	85.46	0.00e+00	1122.00
IUUC-Pan-092158	Papio anubis	87.43	0.00e+00	814.00
IUUC-Psi-092959	Pelodiscus sinensis	58.42	0.00e+00	751.00
IUUC-Pfo-097116	Poecilia formosa	50.30	2.00e-88	320.00
IUUC-Pab-097675	Pongo abelii	85.73	0.00e+00	1110.00
IUUC-Pca-101021	Procavia capensis	76.24	0.00e+00	966.00
IUUC-Pva-102619	Pteropus vampyrus	85.16	0.00e+00	1071.00
IUUC-Rno-105918	Rattus norvegicus	77.96	0.00e+00	1057.00
IUUC-Sha-107391	Sarcophilus harrisii	68.30	0.00e+00	895.00
IUUC-Sja-107661	Schizosaccharomyces japonicus	43.10	1.00e-10	60.80
IUUC-Sar-113148	Sorex araneus	79.08	0.00e+00	632.00
IUUC-Ssc-116219	Sus scrofa	76.66	6.00e-125	439.00
IUUC-Tgu-116584	Taeniopygia guttata	57.18	9.00e-116	409.00
IUUC-Tsy-118968	Tarsius syrichta	80.05	2.00e-163	568.00
IUUC-Tni-120900	Tetraodon nigroviridis	35.94	6.00e-71	262.00
IUUC-Tbe-128007	Tupaia belangeri	88.06	0.00e+00	810.00
IUUC-Ttr-128499	Tursiops truncatus	84.21	0.00e+00	1118.00
IUUC-Vpa-130075	Vicugna pacos	77.65	1.00e-77	283.00
IUUC-Xtr-132333	Xenopus tropicalis	47.91	2.00e-144	506.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence