iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021985

Ensembl Protein ID

ENSCPOP00000018190.1

UniProt Accession

H0W5D8; H0W5D8_CAVPO

Genbank Protein ID

ENSCPOP00000018190

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02010347

Gene Name

LATS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000024403.1	ENSCPOT00000022133.1	ENSCPOP00000018190.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	86.80	0.00e+00	1084.00	IUUC-Hsa-046254

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MRPKTFPATT YSGNSRQRLQ EIREGLKQPP KSSSQGLPMG PHSEAPLDAK VLGSKDATRQ 60
QQMRATPKFG PYQKALREIR YSLLPFANES GTPAVAEVNR QMLQELVNAG CDQEMAGRAL 120

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Nucleotide Sequence
(Fasta)

ATGAGGCCAA AGACTTTTCC TGCTACCACT TACTCTGGAA ATAGCCGGCA GCGACTGCAG 60
GAGATCCGTG AGGGGCTGAA GCAGCCCCCC AAGTCCTCCT CTCAGGGGCT GCCCATGGGA 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005829--C:cytosol
GO:0005815--C:microtubule organizing center
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0034613--P:cellular protein localization
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0001827--P:inner cell mass cell fate commitment
GO:0001828--P:inner cell mass cellular morphogenesis
GO:0030216--P:keratinocyte differentiation
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0046620--P:regulation of organ growth

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001960	Ailuropoda melanoleuca	83.95	0.00e+00	1194.00
IUUC-Aca-004995	Anolis carolinensis	77.36	0.00e+00	1087.00
IUUC-Ame-011481	Astyanax mexicanus	59.64	0.00e+00	1175.00
IUUC-Bta-012618	Bos taurus	78.50	0.00e+00	1014.00
IUUC-Cel-018517	Caenorhabditis elegans	47.98	3.00e-121	429.00
IUUC-Cja-019430	Callithrix jacchus	75.36	0.00e+00	1509.00
IUUC-Cfa-020687	Canis familiaris	84.84	0.00e+00	1173.00
IUUC-Csa-023534	Chlorocebus sabaeus	95.67	0.00e+00	965.00
IUUC-Cin-025264	Ciona intestinalis	62.80	8.00e-136	476.00
IUUC-Dre-027538	Danio rerio	59.39	0.00e+00	1166.00
IUUC-Dno-029126	Dasypus novemcinctus	83.36	0.00e+00	1154.00
IUUC-Dor-030172	Dipodomys ordii	85.30	0.00e+00	1115.00
IUUC-Dme-031656	Drosophila melanogaster	72.54	0.00e+00	631.00
IUUC-Eca-033868	Equus caballus	84.38	0.00e+00	1175.00
IUUC-Eeu-034881	Erinaceus europaeus	77.73	0.00e+00	1054.00
IUUC-Fca-036203	Felis catus	80.74	0.00e+00	1110.00
IUUC-Fal-036668	Ficedula albicollis	77.18	0.00e+00	1089.00
IUUC-Gmo-039195	Gadus morhua	84.65	0.00e+00	772.00
IUUC-Gac-041789	Gasterosteus aculeatus	60.29	0.00e+00	1108.00
IUUC-Ggo-044904	Gorilla gorilla	74.25	0.00e+00	1466.00
IUUC-Hsa-046254	Homo sapiens	73.16	0.00e+00	1459.00
IUUC-Itr-047948	Ictidomys tridecemlineatus	76.17	0.00e+00	1317.00
IUUC-Lch-050079	Latimeria chalumnae	74.21	0.00e+00	1045.00
IUUC-Loc-052265	Lepisosteus oculatus	71.78	0.00e+00	910.00
IUUC-Laf-053806	Loxodonta africana	72.22	0.00e+00	1510.00
IUUC-Mcc-055253	Macaca mulatta	84.97	0.00e+00	1124.00
IUUC-Meu-056509	Macropus eugenii	83.15	0.00e+00	792.00
IUUC-Mga-059600	Meleagris gallopavo	78.74	0.00e+00	1124.00
IUUC-Mmr-061586	Microcebus murinus	74.36	0.00e+00	1463.00
IUUC-Mdo-062126	Monodelphis domestica	78.43	0.00e+00	1098.00
IUUC-Mmu-063164	Mus musculus	74.63	0.00e+00	1468.00
IUUC-Mpu-065992	Mustela putorius furo	84.70	0.00e+00	1199.00
IUUC-Mlu-067728	Myotis lucifugus	82.84	0.00e+00	1120.00
IUUC-Nle-069546	Nomascus leucogenys	73.33	0.00e+00	1471.00
IUUC-Opr-070872	Ochotona princeps	74.26	0.00e+00	1436.00
IUUC-Ont-072296	Oreochromis niloticus	69.15	0.00e+00	956.00
IUUC-Ocu-074068	Oryctolagus cuniculus	75.67	0.00e+00	1508.00
IUUC-Ola-086756	Oryzias latipes	71.39	0.00e+00	943.00
IUUC-Oga-089066	Otolemur garnettii	76.87	0.00e+00	1522.00
IUUC-Oar-090416	Ovis aries	82.27	0.00e+00	979.00
IUUC-Ptr-091247	Pan troglodytes	74.25	0.00e+00	1499.00
IUUC-Pan-092438	Papio anubis	85.12	0.00e+00	1127.00
IUUC-Psi-093920	Pelodiscus sinensis	79.08	0.00e+00	1099.00
IUUC-Pfo-096334	Poecilia formosa	57.51	0.00e+00	1112.00
IUUC-Pab-098452	Pongo abelii	90.31	0.00e+00	1060.00
IUUC-Pca-101081	Procavia capensis	67.33	0.00e+00	1384.00
IUUC-Ptt-103762	Puccinia triticina	36.93	3.00e-90	326.00
IUUC-Rno-105102	Rattus norvegicus	75.19	0.00e+00	1465.00
IUUC-Sha-106917	Sarcophilus harrisii	78.14	0.00e+00	1113.00
IUUC-Sar-113711	Sorex araneus	78.64	0.00e+00	1019.00
IUUC-Tgu-116553	Taeniopygia guttata	77.92	0.00e+00	1109.00
IUUC-Tru-118069	Takifugu rubripes	71.71	0.00e+00	931.00
IUUC-Tni-120617	Tetraodon nigroviridis	68.48	0.00e+00	913.00
IUUC-Ttr-129256	Tursiops truncatus	72.95	0.00e+00	1338.00
IUUC-Xtr-132593	Xenopus tropicalis	65.93	0.00e+00	1330.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence