iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071372

Ensembl Protein ID

ENSONIP00000016960.1

UniProt Accession

I3K765; I3K765_ORENI

Genbank Protein ID

ENSONIP00000016960

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01026859

Gene Name

ube3b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000013487.1	ENSONIT00000016975.1	ENSONIP00000016960.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	7.50e-113	377.7	705	1068

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdg 85
           ++k +++v+fv+     E+g+d++Gv++efl++++k+++np l+lf+++++++  l+p+p+s++++ +hl+lFef+G++lgka+++g
   Q: 705  SIKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKKVFNPALNLFKTTSGNE-RLYPSPTSYIHE-NHLQLFEFVGKMLGKAVYEG 789
           578899****************************************9888655.569*******76.******************** PP
   S: 86   rlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtn 167
            ++d+p++++f++++lg+       s+++l+++d+e+yk+l++ik++ + d+ +lgl+l++  +e+++g+  ++eL+pgG+++pVtn
   Q: 790  IVVDVPFASFFLSQVLGHhhstfYSSIDELPSLDSEFYKNLTSIKRY-DGDVGDLGLTLSY--DEDVMGQLVCHELIPGGKTMPVTN 873
           ******************777777999********************.7899998777776..5999******************** PP
   S: 168  eNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevl 253
           eNk +Y++l++++r++++ikeq++af +Gf+++i++e+l +F++ e++ li+G+ +eid++dlkk+t y gg+++++++i+w+w++l
   Q: 874  ENKISYIHLMAHFRMHTQIKEQTAAFIRGFRSIINPEWLHMFSTPEVQRLISGDnAEIDLDDLKKHTVYYGGFHSSHRVIIWLWDIL 960
           ******************************************************9******************************** PP
   S: 254  .eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeYss 315
            ++f++eer++fL+FvT++sr Pl Gfa+lk                        + +f+irk +   rlP+s+TCfn+LkLP+Ys+
   Q: 961  sSDFNAEERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSK 1047
           999************************************************************8888******************** PP
   S: 316  keilkekLlyAieetkgFels 336
           k+il++kL+yAi++++gFels
   Q: 1048 KSILRDKLRYAISMNTGFELS 1068
           ******************985 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MFSVPQSSKS EFLDKARQAR EERKGQKEKE RAAIIIQALV RRFICRCRLQ KQIRKEIDDY 60
FQASETGTSK RNALSIFKIA RKLLFIYCQE DKMRFEKLCR AILASMEVEN EPKVWYVSLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGCACGAT GTTTAGTGTA CCTCAAAGCT CCAAGTCCGA GTTCCTGGAC AAAGCCAGGC 60
AGGCCAGAGA GGAGAGAAAG GGGCAGAAGG AGAAGGAGAG AGCAGCAATT ATCATTCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.86	3.00e-107	383.00
IUUC-Aml-002107	Ailuropoda melanoleuca	81.95	0.00e+00	1800.00
IUUC-Atr-003017	Amborella trichopoda	40.07	1.00e-114	408.00
IUUC-Apl-003328	Anas platyrhynchos	85.16	0.00e+00	1781.00
IUUC-Aly-005794	Arabidopsis lyrata	39.64	4.00e-109	389.00
IUUC-Ath-007269	Arabidopsis thaliana	40.18	3.00e-112	400.00
IUUC-Bta-013547	Bos taurus	81.76	0.00e+00	1821.00
IUUC-Bdi-014502	Brachypodium distachyon	39.86	1.00e-111	398.00
IUUC-Bol-015093	Brassica oleracea	40.36	8.00e-113	402.00
IUUC-Bra-016722	Brassica rapa	40.54	7.00e-114	405.00
IUUC-Cel-018447	Caenorhabditis elegans	39.56	0.00e+00	682.00
IUUC-Cja-019855	Callithrix jacchus	81.38	0.00e+00	1795.00
IUUC-Cfa-020066	Canis familiaris	82.14	0.00e+00	1782.00
IUUC-Cpo-021504	Cavia porcellus	81.85	0.00e+00	1828.00
IUUC-Csa-023579	Chlorocebus sabaeus	81.57	0.00e+00	1797.00
IUUC-Cho-024430	Choloepus hoffmanni	71.61	0.00e+00	1295.00
IUUC-Cin-025750	Ciona intestinalis	45.65	0.00e+00	952.00
IUUC-Csv-026016	Ciona savignyi	46.31	0.00e+00	1000.00
IUUC-Dre-028271	Danio rerio	91.39	0.00e+00	1937.00
IUUC-Dno-029054	Dasypus novemcinctus	82.41	0.00e+00	1812.00
IUUC-Dor-030938	Dipodomys ordii	86.41	0.00e+00	1109.00
IUUC-Dme-031602	Drosophila melanogaster	48.71	0.00e+00	976.00
IUUC-Ete-033041	Echinops telfairi	66.38	0.00e+00	1191.00
IUUC-Eca-034411	Equus caballus	82.32	0.00e+00	1788.00
IUUC-Eeu-035201	Erinaceus europaeus	77.37	0.00e+00	749.00
IUUC-Fca-036594	Felis catus	80.92	0.00e+00	1762.00
IUUC-Fal-037317	Ficedula albicollis	76.14	0.00e+00	1630.00
IUUC-Gmo-039412	Gadus morhua	89.94	0.00e+00	1963.00
IUUC-Gga-040149	Gallus gallus	85.33	0.00e+00	1833.00
IUUC-Gac-042088	Gasterosteus aculeatus	95.33	0.00e+00	2076.00
IUUC-Gma-043839	Glycine max	40.85	4.00e-113	402.00
IUUC-Ggo-045279	Gorilla gorilla	81.57	0.00e+00	1796.00
IUUC-Hsa-045660	Homo sapiens	81.38	0.00e+00	1791.00
IUUC-Hvu-047770	Hordeum vulgare	37.70	1.00e-109	390.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	74.53	0.00e+00	851.00
IUUC-Lch-050664	Latimeria chalumnae	86.37	0.00e+00	1899.00
IUUC-Lpe-051428	Leersia perrieri	34.51	2.00e-98	354.00
IUUC-Loc-052791	Lepisosteus oculatus	91.99	0.00e+00	1946.00
IUUC-Laf-053902	Loxodonta africana	82.51	0.00e+00	1815.00
IUUC-Mcc-054730	Macaca mulatta	81.48	0.00e+00	1796.00
IUUC-Meu-056527	Macropus eugenii	77.05	0.00e+00	1628.00
IUUC-Mtr-057671	Medicago truncatula	40.50	2.00e-112	400.00
IUUC-Mga-059260	Meleagris gallopavo	84.98	0.00e+00	1829.00
IUUC-Mmr-060804	Microcebus murinus	81.29	0.00e+00	1759.00
IUUC-Mdo-062575	Monodelphis domestica	80.49	0.00e+00	1723.00
IUUC-Mmu-063636	Mus musculus	80.58	0.00e+00	1727.00
IUUC-Mac-064989	Musa acuminata	40.00	3.00e-110	393.00
IUUC-Mpu-066677	Mustela putorius furo	80.82	0.00e+00	1674.00
IUUC-Mlu-067952	Myotis lucifugus	82.60	0.00e+00	1746.00
IUUC-Nle-069153	Nomascus leucogenys	81.57	0.00e+00	1793.00
IUUC-Opr-070554	Ochotona princeps	81.61	0.00e+00	1650.00
IUUC-Oan-073327	Ornithorhynchus anatinus	69.51	0.00e+00	738.00
IUUC-Ocu-074183	Oryctolagus cuniculus	80.37	0.00e+00	1778.00
IUUC-Oba-075006	Oryza barthii	37.24	4.00e-112	399.00
IUUC-Obr-076133	Oryza brachyantha	36.46	8.00e-112	399.00
IUUC-Ogl-077003	Oryza glaberrima	37.24	5.00e-112	399.00
IUUC-Ogu-078947	Oryza glumaepatula	37.48	7.00e-113	402.00
IUUC-Oin-080058	Oryza indica	39.62	9.00e-110	392.00
IUUC-Olo-080475	Oryza longistaminata	37.66	7.00e-113	402.00
IUUC-Ome-081741	Oryza meridionalis	39.22	1.00e-102	368.00
IUUC-Oni-082385	Oryza nivara	37.48	7.00e-113	402.00
IUUC-Opu-083176	Oryza punctata	37.95	2.00e-111	397.00
IUUC-Oru-084554	Oryza rufipogon	35.28	7.00e-100	358.00
IUUC-Osa-085355	Oryza sativa	37.38	7.00e-113	402.00
IUUC-Ola-087337	Oryzias latipes	95.69	0.00e+00	1986.00
IUUC-Oga-088342	Otolemur garnettii	81.03	0.00e+00	1716.00
IUUC-Oar-090234	Ovis aries	81.19	0.00e+00	1789.00
IUUC-Ptr-091661	Pan troglodytes	81.57	0.00e+00	1796.00
IUUC-Pan-092728	Papio anubis	81.31	0.00e+00	1790.00
IUUC-Psi-093251	Pelodiscus sinensis	84.61	0.00e+00	1690.00
IUUC-Pma-094195	Petromyzon marinus	70.55	0.00e+00	1464.00
IUUC-Ppa-095544	Physcomitrella patens	38.20	2.00e-112	401.00
IUUC-Pfo-097472	Poecilia formosa	97.38	0.00e+00	2073.00
IUUC-Pab-098570	Pongo abelii	81.76	0.00e+00	1796.00
IUUC-Pca-100110	Procavia capensis	71.94	0.00e+00	1510.00
IUUC-Ppe-101281	Prunus persica	39.72	7.00e-108	385.00
IUUC-Pva-102887	Pteropus vampyrus	77.38	0.00e+00	1665.00
IUUC-Rno-106028	Rattus norvegicus	78.08	0.00e+00	1654.00
IUUC-Sha-107331	Sarcophilus harrisii	81.53	0.00e+00	1755.00
IUUC-Smo-109488	Selaginella moellendorffii	37.79	2.00e-107	384.00
IUUC-Sit-109811	Setaria italica	39.79	7.00e-110	392.00
IUUC-Sar-113287	Sorex araneus	68.97	2.00e-161	563.00
IUUC-Sbi-114433	Sorghum bicolor	40.29	1.00e-110	394.00
IUUC-Ssc-116103	Sus scrofa	82.51	0.00e+00	1789.00
IUUC-Tgu-117275	Taeniopygia guttata	84.21	0.00e+00	1808.00
IUUC-Tru-118681	Takifugu rubripes	94.66	0.00e+00	2060.00
IUUC-Tsy-118985	Tarsius syrichta	72.12	0.00e+00	833.00
IUUC-Tni-120850	Tetraodon nigroviridis	98.75	0.00e+00	827.00
IUUC-Tca-121770	Theobroma cacao	39.72	4.00e-112	399.00
IUUC-Tae-125466	Triticum aestivum	36.82	1.00e-109	391.00
IUUC-Tur-126086	Triticum urartu	39.79	2.00e-106	381.00
IUUC-Tbe-127461	Tupaia belangeri	78.02	0.00e+00	1640.00
IUUC-Ttr-129269	Tursiops truncatus	81.95	0.00e+00	1761.00
IUUC-Vpa-130523	Vicugna pacos	72.85	3.00e-112	399.00
IUUC-Vvi-131524	Vitis vinifera	39.68	3.00e-110	393.00
IUUC-Xtr-132146	Xenopus tropicalis	82.74	0.00e+00	1831.00
IUUC-Xma-133526	Xiphophorus maculatus	96.91	0.00e+00	2062.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence