iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035391

Ensembl Protein ID

ENSFCAP00000024152.1

UniProt Accession

M3XBZ8; M3XBZ8_FELCA

Genbank Protein ID

ENSFCAP00000024152

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AANG02107875

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000030968.1	ENSFCAT00000025970.1	ENSFCAP00000024152.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.30e-09	36.4	207	254

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 207  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 254
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Felis catus

Protein Sequence
(Fasta)

IHLVNYVEDY LDSIESLPFD LQRNVSLMRE RLQRVSGKKK SEILKELDEY YEKFKRETDG 60
VQKRRVLHCI QRALIRSQEL GDEKIQIVSQ MVELVENRTR QVDSHVELFE AHQEVNDTTG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCCACCTGG TGAACTATGT GGAGGACTAC CTGGACTCCA TCGAGTCTCT GCCATTCGAC 60
CTGCAGAGAA ACGTCTCGCT GATGCGGGAG ATNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	94.59	2.00e-116	411.00
IUUC-Apl-003910	Anas platyrhynchos	88.03	2.00e-108	384.00
IUUC-Aca-004874	Anolis carolinensis	87.64	2.00e-107	381.00
IUUC-Ame-011262	Astyanax mexicanus	64.07	2.00e-80	291.00
IUUC-Bta-013507	Bos taurus	90.37	8.00e-85	306.00
IUUC-Cja-018925	Callithrix jacchus	86.10	5.00e-105	373.00
IUUC-Cfa-020947	Canis familiaris	93.82	1.00e-114	405.00
IUUC-Cpo-022286	Cavia porcellus	90.87	1.00e-92	332.00
IUUC-Csa-023825	Chlorocebus sabaeus	85.71	2.00e-104	372.00
IUUC-Cho-024577	Choloepus hoffmanni	93.09	8.00e-94	335.00
IUUC-Dno-029834	Dasypus novemcinctus	90.35	1.00e-111	395.00
IUUC-Dor-030315	Dipodomys ordii	88.13	8.00e-94	337.00
IUUC-Ete-032408	Echinops telfairi	80.88	3.00e-89	321.00
IUUC-Eca-034244	Equus caballus	94.95	4.00e-96	343.00
IUUC-Fal-036838	Ficedula albicollis	87.26	2.00e-107	381.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	90.90
IUUC-Gga-040619	Gallus gallus	87.26	4.00e-107	380.00
IUUC-Gac-041996	Gasterosteus aculeatus	60.77	2.00e-75	275.00
IUUC-Ggo-045481	Gorilla gorilla	87.61	4.00e-88	318.00
IUUC-Hsa-046170	Homo sapiens	87.61	5.00e-88	318.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	94.50	8.00e-97	345.00
IUUC-Lch-050397	Latimeria chalumnae	84.17	1.00e-103	369.00
IUUC-Loc-052038	Lepisosteus oculatus	79.23	9.00e-97	345.00
IUUC-Laf-054126	Loxodonta africana	90.35	5.00e-112	396.00
IUUC-Mcc-055031	Macaca mulatta	84.12	1.00e-88	319.00
IUUC-Meu-056248	Macropus eugenii	92.69	5.00e-93	333.00
IUUC-Mga-059217	Meleagris gallopavo	89.91	3.00e-91	327.00
IUUC-Mmr-061581	Microcebus murinus	91.86	7.00e-95	339.00
IUUC-Mdo-062452	Monodelphis domestica	89.96	5.00e-110	390.00
IUUC-Mmu-063412	Mus musculus	89.19	5.00e-110	390.00
IUUC-Mpu-066479	Mustela putorius furo	97.72	4.00e-100	357.00
IUUC-Mlu-067586	Myotis lucifugus	79.54	3.00e-103	367.00
IUUC-Nle-069122	Nomascus leucogenys	85.33	6.00e-104	370.00
IUUC-Opr-070835	Ochotona princeps	86.64	3.00e-78	284.00
IUUC-Oan-073023	Ornithorhynchus anatinus	86.87	1.00e-104	372.00
IUUC-Ocu-073779	Oryctolagus cuniculus	89.50	8.00e-87	313.00
IUUC-Ola-086891	Oryzias latipes	62.65	9.00e-76	276.00
IUUC-Oga-087954	Otolemur garnettii	89.58	7.00e-111	392.00
IUUC-Oar-090006	Ovis aries	88.42	1.00e-106	379.00
IUUC-Ptr-090589	Pan troglodytes	85.71	1.00e-104	372.00
IUUC-Pan-091896	Papio anubis	84.12	7.00e-89	320.00
IUUC-Psi-093266	Pelodiscus sinensis	88.80	3.00e-109	387.00
IUUC-Pfo-097531	Poecilia formosa	58.10	1.00e-73	269.00
IUUC-Pab-098253	Pongo abelii	85.71	3.00e-104	371.00
IUUC-Pva-102753	Pteropus vampyrus	83.33	4.00e-86	311.00
IUUC-Rno-105964	Rattus norvegicus	90.83	1.00e-82	298.00
IUUC-Sha-107270	Sarcophilus harrisii	89.19	2.00e-108	385.00
IUUC-Tgu-116822	Taeniopygia guttata	87.64	8.00e-108	382.00
IUUC-Tni-119980	Tetraodon nigroviridis	57.09	2.00e-66	245.00
IUUC-Tvi-122341	Trichoderma virens	62.50	3.00e-16	77.40
IUUC-Ttr-128672	Tursiops truncatus	94.95	5.00e-94	337.00
IUUC-Xtr-132200	Xenopus tropicalis	80.69	5.00e-97	347.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence