iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062511

Ensembl Protein ID

ENSMODP00000028701.1

UniProt Accession

F7DT27; F7DT27_MONDO

Protein Name

Uncharacterized protein

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000010600.3	ENSMODT00000030283.1	ENSMODP00000028701.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	9.70e-13	48.5	47	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk vLaasS ++++l  +        +  +++ d v+p vfr +l+F+Ytg+l
   Q: 47   CDVIIVVQNALFRAHKNVLAASSAYLKSLVVH-------DNLLNLDhDmVSPAVFRLVLDFIYTGRL 106
           9*****************************77.......4566677678****************98 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MTFSEADVSL NPGGSTGQTM LDAMEAPGHS RQLLLQLNSQ RTKGFLCDVI IVVQNALFRA 60
HKNVLAASSA YLKSLVVHDN LLNLDHDMVS PAVFRLVLDF IYTGRLADGA DGGAAAAAPG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTTTTT CTGAAGCGGA CGTTTCCCTG AACCCGGGTA ACTCCTGAGG CGGACATTTT 60
CCCCCGGAGC GGATTTAGTT TGGGAAATCC CCCGCCCGGG CCCCGACCCT TCTCTGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	82.27	2.00e-91	330.00
IUUC-Bta-013567	Bos taurus	84.16	7.00e-95	341.00
IUUC-Cja-019621	Callithrix jacchus	95.79	9.00e-45	171.00
IUUC-Cfa-020731	Canis familiaris	59.27	1.00e-133	470.00
IUUC-Cpo-021326	Cavia porcellus	59.12	2.00e-132	466.00
IUUC-Csa-023645	Chlorocebus sabaeus	57.82	5.00e-134	471.00
IUUC-Dno-028900	Dasypus novemcinctus	56.93	6.00e-137	481.00
IUUC-Fal-036980	Ficedula albicollis	62.01	2.00e-98	353.00
IUUC-Gga-040708	Gallus gallus	57.62	1.00e-165	576.00
IUUC-Ggo-044591	Gorilla gorilla	84.16	7.00e-96	344.00
IUUC-Hsa-046769	Homo sapiens	57.82	2.00e-133	469.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	56.66	1.00e-133	470.00
IUUC-Lch-049412	Latimeria chalumnae	54.09	2.00e-167	582.00
IUUC-Laf-053358	Loxodonta africana	84.16	2.00e-95	343.00
IUUC-Mcc-054981	Macaca mulatta	57.82	1.00e-127	450.00
IUUC-Meu-056181	Macropus eugenii	79.91	6.00e-129	454.00
IUUC-Mga-059592	Meleagris gallopavo	73.56	1.00e-91	330.00
IUUC-Mmr-061560	Microcebus murinus	55.86	8.00e-131	461.00
IUUC-Mmu-064258	Mus musculus	58.58	1.00e-133	471.00
IUUC-Mpu-065911	Mustela putorius furo	58.81	5.00e-129	454.00
IUUC-Mlu-067575	Myotis lucifugus	80.31	1.00e-84	307.00
IUUC-Ola-086584	Oryzias latipes	60.00	4.00e-81	295.00
IUUC-Oga-088774	Otolemur garnettii	59.12	4.00e-147	514.00
IUUC-Ptr-090491	Pan troglodytes	84.16	2.00e-96	346.00
IUUC-Pab-098488	Pongo abelii	84.16	8.00e-96	344.00
IUUC-Pca-100667	Procavia capensis	83.71	1.00e-96	347.00
IUUC-Pva-102421	Pteropus vampyrus	83.26	8.00e-97	348.00
IUUC-Rno-105528	Rattus norvegicus	54.79	1.00e-134	473.00
IUUC-Sar-113478	Sorex araneus	83.71	8.00e-96	344.00
IUUC-Ssc-115420	Sus scrofa	83.26	8.00e-97	348.00
IUUC-Tgu-116642	Taeniopygia guttata	58.12	5.00e-164	571.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence