iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054255

UUCD1 version

UUC-LoA-00044

Ensembl Protein ID

ENSLAFP00000001227.3

UniProt Accession

G3SNL7; G3SNL7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000001471.3	ENSLAFT00000001471.3	ENSLAFP00000001227.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-40	134.6	279	315
UBD/Beta-Prp	3.20e-52	177.9	189	393

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           +H+++++++++ ++ + ++sGsdD t++++Dlr ++ 
   Q: 279  THESDINSVRYyPSgDAFASGSDDATCRLYDLRADRE 315
           5*********99666*****************99875 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh+++vl+l++ p  +g+++vsG+ d+ ++vwd+++gq ++  
   Q: 189  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHTADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQRVQ-A 276
           567889999*********99***************************************9778************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 277  FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESILFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 365
           *******************************************4333456778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiri 248
           h++ v+ +r+sp+++ + sgs D ++r+
   Q: 366  HENRVSTLRVSPDGTAFCSGSWDHTLRV 393
           ************************9986 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MCDQTFLVNV FGSCDKCLKQ RALRPVFKKS QQLSYCSICA EIMATDGLHE NETLAALKSE 60
AESLKGKLEE ERAKLHDVEL HQVAERVEAL GQFVMKTRRT LKGHGNKVLC MDWCKDKRRM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGACC AGACCTTTCT AGTTAACGTA TTTGGCTCCT GTGACAAGTG TTTAAAACAA 60
AGGGCTCTGA GGCCAGTTTT CAAGAAATCT CAACAACTCA GCTACTGTTC AATATGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	91.86	0.00e+00	753.00
IUUC-Apl-003399	Anas platyrhynchos	97.44	0.00e+00	642.00
IUUC-Aca-004861	Anolis carolinensis	91.86	0.00e+00	765.00
IUUC-Ame-011851	Astyanax mexicanus	91.17	0.00e+00	679.00
IUUC-Bta-012438	Bos taurus	98.29	0.00e+00	718.00
IUUC-Cel-018408	Caenorhabditis elegans	64.72	5.00e-137	480.00
IUUC-Cja-019086	Callithrix jacchus	97.96	0.00e+00	805.00
IUUC-Cfa-021255	Canis familiaris	95.93	0.00e+00	749.00
IUUC-Cpo-021398	Cavia porcellus	96.19	0.00e+00	786.00
IUUC-Csa-023776	Chlorocebus sabaeus	98.01	0.00e+00	717.00
IUUC-Cin-025305	Ciona intestinalis	57.42	1.00e-128	452.00
IUUC-Csv-026058	Ciona savignyi	57.81	2.00e-126	445.00
IUUC-Dre-028432	Danio rerio	83.97	0.00e+00	674.00
IUUC-Dno-029958	Dasypus novemcinctus	86.90	1.00e-146	511.00
IUUC-Dor-031013	Dipodomys ordii	98.43	3.00e-150	524.00
IUUC-Dme-031889	Drosophila melanogaster	67.54	1.00e-146	512.00
IUUC-Ete-033033	Echinops telfairi	68.88	3.00e-152	531.00
IUUC-Eca-033977	Equus caballus	92.11	0.00e+00	751.00
IUUC-Eeu-035079	Erinaceus europaeus	96.67	0.00e+00	784.00
IUUC-Fca-035693	Felis catus	90.89	0.00e+00	746.00
IUUC-Fal-037345	Ficedula albicollis	96.87	0.00e+00	713.00
IUUC-Gmo-039222	Gadus morhua	90.31	0.00e+00	648.00
IUUC-Gga-040320	Gallus gallus	96.87	0.00e+00	714.00
IUUC-Gac-042644	Gasterosteus aculeatus	90.60	0.00e+00	677.00
IUUC-Ggo-044489	Gorilla gorilla	93.92	0.00e+00	761.00
IUUC-Hsa-046434	Homo sapiens	97.96	0.00e+00	804.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	92.41	3.00e-174	603.00
IUUC-Loc-052790	Lepisosteus oculatus	89.29	0.00e+00	718.00
IUUC-Mcc-055610	Macaca mulatta	97.46	0.00e+00	800.00
IUUC-Meu-056819	Macropus eugenii	85.20	0.00e+00	685.00
IUUC-Mga-059740	Meleagris gallopavo	86.22	0.00e+00	705.00
IUUC-Mmr-061221	Microcebus murinus	97.71	0.00e+00	802.00
IUUC-Mdo-062619	Monodelphis domestica	96.58	0.00e+00	711.00
IUUC-Mmu-064266	Mus musculus	97.71	0.00e+00	803.00
IUUC-Mpu-065766	Mustela putorius furo	97.99	1.00e-177	615.00
IUUC-Mlu-067221	Myotis lucifugus	89.87	0.00e+00	734.00
IUUC-Nle-069515	Nomascus leucogenys	98.41	0.00e+00	647.00
IUUC-Opr-070195	Ochotona princeps	89.51	0.00e+00	716.00
IUUC-Ont-071535	Oreochromis niloticus	78.63	4.00e-172	597.00
IUUC-Oan-072899	Ornithorhynchus anatinus	96.22	5.00e-105	372.00
IUUC-Ocu-074666	Oryctolagus cuniculus	98.33	5.00e-178	616.00
IUUC-Ola-086578	Oryzias latipes	91.74	0.00e+00	644.00
IUUC-Oga-089090	Otolemur garnettii	97.47	0.00e+00	798.00
IUUC-Oar-090017	Ovis aries	91.07	0.00e+00	730.00
IUUC-Ptr-091280	Pan troglodytes	88.80	0.00e+00	712.00
IUUC-Pan-092198	Papio anubis	97.78	0.00e+00	647.00
IUUC-Psi-093030	Pelodiscus sinensis	84.50	0.00e+00	706.00
IUUC-Pma-094140	Petromyzon marinus	82.16	1.00e-103	368.00
IUUC-Pfo-097182	Poecilia formosa	91.45	0.00e+00	655.00
IUUC-Pab-098157	Pongo abelii	98.29	0.00e+00	721.00
IUUC-Pca-100988	Procavia capensis	77.35	3.00e-169	587.00
IUUC-Pva-102232	Pteropus vampyrus	85.71	3.00e-175	607.00
IUUC-Rno-105526	Rattus norvegicus	94.65	0.00e+00	687.00
IUUC-Sce-106298	Saccharomyces cerevisiae	34.95	8.00e-67	247.00
IUUC-Sha-106754	Sarcophilus harrisii	95.42	0.00e+00	744.00
IUUC-Ssc-115390	Sus scrofa	97.72	0.00e+00	801.00
IUUC-Tgu-117377	Taeniopygia guttata	86.70	0.00e+00	696.00
IUUC-Tru-117938	Takifugu rubripes	91.45	0.00e+00	644.00
IUUC-Tsy-119392	Tarsius syrichta	83.72	0.00e+00	651.00
IUUC-Tni-119834	Tetraodon nigroviridis	72.26	3.00e-165	574.00
IUUC-Tbe-127469	Tupaia belangeri	94.92	0.00e+00	720.00
IUUC-Ttr-128252	Tursiops truncatus	94.16	0.00e+00	759.00
IUUC-Vpa-130173	Vicugna pacos	79.76	1.00e-155	542.00
IUUC-Xtr-131803	Xenopus tropicalis	90.33	0.00e+00	717.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence