iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069515

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01034822

Gene Name

GNB5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000006486.2	ENSNLET00000008274.2	ENSNLEP00000007896.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.30e-43	142.7	190	230
UBD/Beta-Prp	9.50e-55	185.8	144	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllk 37
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++
   Q: 190  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCVQ 230
           8***********9644499********************98 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++  
   Q: 144  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCVQ-A 231
           567889999*********99***************************************9778************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 232  FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 320
           *******************************************5333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriW 249
           h++ v+ +r+sp+++ + sgs D ++r+W
   Q: 321  HENRVSTLRVSPDGTAFCSGSWDHTLRVW 349
           ***************************** PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MGLPPSAEHT SVLCQPKAQN LVLSKGTDYG LVFPVHQVAE RVEALGQFVM KTRRTLKGHG 60
NKVLCMDWCK DKRRIVSSSQ DGKVIVWDSF TTNKEHAVTM PCTWVMACAY APSGCAIACG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCTGC CTCCCTCTGC AGAGCATACG TCTGTGCTGT GCCAGCCCAA AGCCCAGAAC 60
CTGGTCCTTA GCAAGGGGAC TGACTATGGC CTTGTCTTTC CAGTGCACCA GGTGGCAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	99.68	0.00e+00	660.00
IUUC-Apl-003399	Anas platyrhynchos	99.04	0.00e+00	649.00
IUUC-Aca-004861	Anolis carolinensis	97.47	0.00e+00	653.00
IUUC-Ame-011851	Astyanax mexicanus	94.90	0.00e+00	636.00
IUUC-Bta-012438	Bos taurus	99.37	0.00e+00	660.00
IUUC-Cel-018408	Caenorhabditis elegans	66.35	1.00e-131	462.00
IUUC-Cja-019086	Callithrix jacchus	99.68	0.00e+00	656.00
IUUC-Cfa-021255	Canis familiaris	99.68	0.00e+00	654.00
IUUC-Cpo-021398	Cavia porcellus	98.42	0.00e+00	649.00
IUUC-Csa-023776	Chlorocebus sabaeus	99.68	0.00e+00	662.00
IUUC-Cin-025305	Ciona intestinalis	61.30	4.00e-123	434.00
IUUC-Csv-026058	Ciona savignyi	61.42	2.00e-122	431.00
IUUC-Dre-028572	Danio rerio	93.67	0.00e+00	634.00
IUUC-Dno-029958	Dasypus novemcinctus	87.33	4.00e-112	397.00
IUUC-Dor-031013	Dipodomys ordii	99.22	2.00e-152	531.00
IUUC-Dme-031889	Drosophila melanogaster	68.79	1.00e-137	482.00
IUUC-Eca-033977	Equus caballus	99.68	0.00e+00	659.00
IUUC-Eeu-035079	Erinaceus europaeus	99.37	0.00e+00	659.00
IUUC-Fca-035693	Felis catus	95.83	0.00e+00	665.00
IUUC-Fal-037345	Ficedula albicollis	98.10	0.00e+00	656.00
IUUC-Gmo-039222	Gadus morhua	93.67	0.00e+00	634.00
IUUC-Gga-040320	Gallus gallus	98.42	0.00e+00	658.00
IUUC-Gac-042644	Gasterosteus aculeatus	93.99	0.00e+00	636.00
IUUC-Ggo-044489	Gorilla gorilla	99.68	0.00e+00	659.00
IUUC-Hsa-046434	Homo sapiens	99.68	0.00e+00	661.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	94.30	2.00e-177	614.00
IUUC-Loc-052790	Lepisosteus oculatus	96.49	0.00e+00	640.00
IUUC-Laf-054255	Loxodonta africana	98.41	0.00e+00	647.00
IUUC-Mcc-055610	Macaca mulatta	99.68	0.00e+00	657.00
IUUC-Meu-056819	Macropus eugenii	96.79	3.00e-180	624.00
IUUC-Mga-059740	Meleagris gallopavo	97.81	0.00e+00	657.00
IUUC-Mmr-061221	Microcebus murinus	99.37	0.00e+00	659.00
IUUC-Mdo-062619	Monodelphis domestica	99.05	0.00e+00	660.00
IUUC-Mmu-064266	Mus musculus	99.37	0.00e+00	659.00
IUUC-Mpu-065766	Mustela putorius furo	99.34	0.00e+00	625.00
IUUC-Mlu-067221	Myotis lucifugus	96.88	0.00e+00	649.00
IUUC-Opr-070195	Ochotona princeps	88.92	3.00e-165	574.00
IUUC-Ont-071535	Oreochromis niloticus	84.18	8.00e-156	543.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.84	7.00e-107	379.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.67	0.00e+00	626.00
IUUC-Ola-086578	Oryzias latipes	94.60	0.00e+00	634.00
IUUC-Oga-089090	Otolemur garnettii	99.06	0.00e+00	655.00
IUUC-Oar-090017	Ovis aries	99.05	0.00e+00	652.00
IUUC-Ptr-091280	Pan troglodytes	99.68	0.00e+00	658.00
IUUC-Pan-092198	Papio anubis	98.86	0.00e+00	720.00
IUUC-Psi-093030	Pelodiscus sinensis	90.86	0.00e+00	655.00
IUUC-Pfo-097182	Poecilia formosa	94.30	0.00e+00	637.00
IUUC-Pab-098157	Pongo abelii	99.68	0.00e+00	662.00
IUUC-Pca-100988	Procavia capensis	72.87	5.00e-125	440.00
IUUC-Pva-102232	Pteropus vampyrus	100.00	7.00e-161	559.00
IUUC-Rno-105526	Rattus norvegicus	95.28	8.00e-180	622.00
IUUC-Sha-106754	Sarcophilus harrisii	99.05	0.00e+00	657.00
IUUC-Ssc-115390	Sus scrofa	99.05	0.00e+00	655.00
IUUC-Tgu-117377	Taeniopygia guttata	95.73	0.00e+00	654.00
IUUC-Tru-117938	Takifugu rubripes	94.30	0.00e+00	635.00
IUUC-Tsy-119392	Tarsius syrichta	84.91	3.00e-154	538.00
IUUC-Tni-119834	Tetraodon nigroviridis	77.22	7.00e-148	516.00
IUUC-Tbe-127469	Tupaia belangeri	96.85	0.00e+00	627.00
IUUC-Ttr-128252	Tursiops truncatus	98.73	0.00e+00	649.00
IUUC-Vpa-130173	Vicugna pacos	91.41	2.00e-137	481.00
IUUC-Xtr-131803	Xenopus tropicalis	97.15	0.00e+00	650.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence