iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048440

Ensembl Protein ID

ENSSTOP00000019167.1

UniProt Accession

I3N471; I3N471_ICTTR

Genbank Protein ID

ENSSTOP00000019167

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AGTP01004016

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000026920.1	ENSSTOT00000023101.1	ENSSTOP00000019167.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.40e-09	36.8	166	213

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 166  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 213
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

EILKELDEYY EKFKRETDGA QKRRVLHCIQ RALIRSQELG DEKIQIVSQM VELVENRTRQ 60
VDSHVELFET HQEINDTTGN SGKAGQDKSK NETITQAEKP NNKRSRRQRN NENRENASNN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAATCCTGA AGGAATTGGA CGAATATTAC GAGAAATTTA AACGAGAGAC AGATGGTGCC 60
CAGAAACGCC GAGTGTTACA CTGCATCCAG AGAGCCCTGA TTCGGAGCCA GGAACTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	96.58	1.00e-107	382.00
IUUC-Apl-003910	Anas platyrhynchos	95.71	4.00e-104	370.00
IUUC-Aca-004874	Anolis carolinensis	95.73	4.00e-104	370.00
IUUC-Ame-011262	Astyanax mexicanus	69.39	9.00e-77	279.00
IUUC-Bta-013507	Bos taurus	91.03	1.00e-95	341.00
IUUC-Cja-018925	Callithrix jacchus	91.03	4.00e-100	357.00
IUUC-Cfa-020947	Canis familiaris	96.15	2.00e-106	377.00
IUUC-Cpo-022286	Cavia porcellus	94.87	7.00e-104	369.00
IUUC-Csa-023825	Chlorocebus sabaeus	90.60	2.00e-99	355.00
IUUC-Cho-024577	Choloepus hoffmanni	97.00	2.00e-105	374.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	5.00e-16	78.60
IUUC-Dno-029834	Dasypus novemcinctus	97.44	2.00e-107	381.00
IUUC-Dor-030315	Dipodomys ordii	91.45	6.00e-112	397.00
IUUC-Ete-032408	Echinops telfairi	94.42	2.00e-100	358.00
IUUC-Eca-034244	Equus caballus	95.73	9.00e-107	379.00
IUUC-Fca-035391	Felis catus	94.50	4.00e-98	350.00
IUUC-Fal-036838	Ficedula albicollis	94.87	8.00e-104	369.00
IUUC-Fox-037925	Fusarium oxysporum	64.71	1.00e-19	90.50
IUUC-Gga-040619	Gallus gallus	94.44	3.00e-103	367.00
IUUC-Gac-041996	Gasterosteus aculeatus	62.29	3.00e-75	274.00
IUUC-Ggo-045481	Gorilla gorilla	90.17	3.00e-99	355.00
IUUC-Hsa-046170	Homo sapiens	90.17	2.00e-99	355.00
IUUC-Lch-050397	Latimeria chalumnae	89.74	1.00e-98	352.00
IUUC-Loc-052038	Lepisosteus oculatus	81.28	4.00e-82	297.00
IUUC-Laf-054126	Loxodonta africana	97.44	7.00e-108	382.00
IUUC-Mcc-055031	Macaca mulatta	90.17	2.00e-99	355.00
IUUC-Meu-056248	Macropus eugenii	97.42	3.00e-105	374.00
IUUC-Mga-059217	Meleagris gallopavo	94.42	3.00e-102	363.00
IUUC-Mmr-061581	Microcebus murinus	96.15	2.00e-106	378.00
IUUC-Mdo-062452	Monodelphis domestica	97.01	5.00e-106	376.00
IUUC-Mmu-063412	Mus musculus	94.87	7.00e-105	372.00
IUUC-Mpu-066479	Mustela putorius furo	96.58	2.00e-107	381.00
IUUC-Mlu-067723	Myotis lucifugus	96.58	3.00e-107	380.00
IUUC-Nle-069122	Nomascus leucogenys	90.17	5.00e-99	353.00
IUUC-Opr-070835	Ochotona princeps	85.84	2.00e-87	315.00
IUUC-Ont-071606	Oreochromis niloticus	58.46	8.00e-70	256.00
IUUC-Oan-073023	Ornithorhynchus anatinus	93.59	3.00e-101	361.00
IUUC-Ocu-073779	Oryctolagus cuniculus	91.88	7.00e-97	346.00
IUUC-Ola-086891	Oryzias latipes	63.25	2.00e-76	278.00
IUUC-Oga-087954	Otolemur garnettii	95.30	8.00e-106	375.00
IUUC-Oar-090006	Ovis aries	91.45	1.00e-100	359.00
IUUC-Ptr-090589	Pan troglodytes	90.60	1.00e-99	355.00
IUUC-Pan-091896	Papio anubis	90.17	1.00e-99	356.00
IUUC-Psi-093266	Pelodiscus sinensis	95.73	8.00e-105	372.00
IUUC-Pma-094265	Petromyzon marinus	75.34	1.00e-33	135.00
IUUC-Pfo-097531	Poecilia formosa	59.53	3.00e-74	271.00
IUUC-Pab-098253	Pongo abelii	90.60	2.00e-99	354.00
IUUC-Pva-102753	Pteropus vampyrus	92.31	1.00e-95	342.00
IUUC-Rno-105964	Rattus norvegicus	94.02	1.00e-93	335.00
IUUC-Sha-107270	Sarcophilus harrisii	96.15	2.00e-104	371.00
IUUC-Tgu-116822	Taeniopygia guttata	95.30	4.00e-104	370.00
IUUC-Tni-119980	Tetraodon nigroviridis	59.77	5.00e-74	270.00
IUUC-Tvi-122341	Trichoderma virens	62.50	3.00e-16	77.00
IUUC-Ttr-128672	Tursiops truncatus	93.59	2.00e-103	368.00
IUUC-Xtr-132200	Xenopus tropicalis	85.04	5.00e-92	330.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence