iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093334

Ensembl Protein ID

ENSPSIP00000004243.1

UniProt Accession

K7F883; K7F883_PELSI

Genbank Protein ID

ENSPSIP00000004243

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01111542

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000003996.1	ENSPSIT00000004266.1	ENSPSIP00000004243.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.90e-24	84.9	404	475
E3 adaptor/Cullin RING/DCX/DWD	2.60e-42	141.0	96	130
UBD/Beta-Prp	1.10e-54	185.7	3	217

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p+eflCpI+ elM++Pv++++G++y+++++e w++++++++P+t+ pl++  l+Pn tl+  i++w+e+++
   Q: 404  IPDEFLCPITRELMKEPVIAADGYSYEKEAMENWISKKRRSSPMTNLPLHSLVLIPNRTLKMAINRWLETQQ 475
           8*******************************************************************9987 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H ++v+ ++f +d t+lvsG+ Dg+i +W++ + +
   Q: 96   HGSPVRVCRFsPDsTYLVSGAADGSIVLWNVQSLK 130
           99*********999****************98765 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgk..cvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
           kl+++l +h++ v+ + fs++   l+++s D+ti++++l+++   + + lkgh++ v ++ fspsg+ l+s s d t ++wd+++gq l
   Q: 3    KLIHTLVDHSDDVNYCAFSSS--CLASCSLDKTIRLYSLNNFIelPYSPLKGHTYAVHCCCFSPSGHILASCSTDGTTMLWDTHNGQTL 89
           789******************..9****************87512567899************************************** PP
   S: 130  eetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
             ++++h + v++ +++pd+ +lvsG++D+ + lW++++ kl r  +  +++s    +f++ng+ +v+gs  g++++wd +   c++  
   Q: 90   AVLKQPHGSPVRVCRFSPDSTYLVSGAADGSIVLWNVQSLKLYRSGSV-KDGSLVACAFSPNGNLFVTGSSCGDLTIWDDKMR-CLYNE 176
           999999***************************************987.99999999**********************9655.***** PP
   S: 219  nghtdnvksvrfs..........pnderlvsgssDgsiriW 249
           ++h+  v++ +fs          ++  r++s+++D++i++W
   Q: 177  KAHDLGVTCCDFSshtvsdgeqgSRYFRMASCGQDNQIKLW 217
           ****99999999988887776656667899999*******9 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MVKLIHTLVD HSDDVNYCAF SSSCLASCSL DKTIRLYSLN NFIELPYSPL KGHTYAVHCC 60
CFSPSGHILA SCSTDGTTML WDTHNGQTLA VLKQPHGSPV RVCRFSPDST YLVSGAADGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGCTCCCA CCCACCTGGC AGGCCACCCC TACTATCTCC TCCTCCTGGC AGGTTGACAG 60
GCGCCCCGCC CCTCCCATCC TCTCGCCAGC CAGCATCCTA AAAATAAATT GAGCTCAGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

pss:102462608

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	78.78	0.00e+00	774.00
IUUC-Apl-003529	Anas platyrhynchos	81.09	0.00e+00	803.00
IUUC-Aca-004257	Anolis carolinensis	75.31	0.00e+00	741.00
IUUC-Ame-011357	Astyanax mexicanus	51.24	5.00e-111	394.00
IUUC-Bta-013032	Bos taurus	76.31	0.00e+00	752.00
IUUC-Cja-018743	Callithrix jacchus	77.73	0.00e+00	764.00
IUUC-Cfa-021197	Canis familiaris	77.73	0.00e+00	768.00
IUUC-Cpo-022279	Cavia porcellus	78.15	0.00e+00	768.00
IUUC-Csa-023954	Chlorocebus sabaeus	78.78	0.00e+00	771.00
IUUC-Cho-025083	Choloepus hoffmanni	64.81	3.00e-137	481.00
IUUC-Cin-025786	Ciona intestinalis	35.21	3.00e-79	288.00
IUUC-Dre-028087	Danio rerio	55.92	1.00e-138	485.00
IUUC-Dno-028919	Dasypus novemcinctus	79.41	0.00e+00	781.00
IUUC-Dor-031112	Dipodomys ordii	75.63	0.00e+00	741.00
IUUC-Ete-032405	Echinops telfairi	76.32	1.00e-157	548.00
IUUC-Eca-033254	Equus caballus	77.73	0.00e+00	771.00
IUUC-Eeu-034545	Erinaceus europaeus	73.74	0.00e+00	707.00
IUUC-Fca-035482	Felis catus	79.41	0.00e+00	776.00
IUUC-Fal-036976	Ficedula albicollis	65.22	1.00e-170	592.00
IUUC-Gmo-039213	Gadus morhua	54.03	1.00e-131	462.00
IUUC-Gga-040561	Gallus gallus	77.59	0.00e+00	771.00
IUUC-Gac-041471	Gasterosteus aculeatus	57.42	6.00e-135	473.00
IUUC-Ggo-045503	Gorilla gorilla	78.36	0.00e+00	767.00
IUUC-Hsa-045910	Homo sapiens	78.57	0.00e+00	769.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	78.25	2.00e-173	600.00
IUUC-Loc-052307	Lepisosteus oculatus	57.87	1.00e-163	568.00
IUUC-Laf-053587	Loxodonta africana	78.57	0.00e+00	762.00
IUUC-Mcc-055679	Macaca mulatta	78.57	0.00e+00	769.00
IUUC-Meu-055962	Macropus eugenii	67.44	4.00e-174	603.00
IUUC-Mga-059652	Meleagris gallopavo	77.78	0.00e+00	770.00
IUUC-Mmr-060943	Microcebus murinus	76.36	0.00e+00	740.00
IUUC-Mdo-062592	Monodelphis domestica	78.29	0.00e+00	765.00
IUUC-Mmu-063577	Mus musculus	74.37	0.00e+00	717.00
IUUC-Mpu-066422	Mustela putorius furo	79.41	0.00e+00	777.00
IUUC-Mlu-067250	Myotis lucifugus	77.10	0.00e+00	754.00
IUUC-Nle-069517	Nomascus leucogenys	78.36	0.00e+00	769.00
IUUC-Opr-070776	Ochotona princeps	78.15	0.00e+00	756.00
IUUC-Ont-071821	Oreochromis niloticus	57.38	1.00e-146	512.00
IUUC-Oan-073706	Ornithorhynchus anatinus	81.68	0.00e+00	805.00
IUUC-Ocu-074766	Oryctolagus cuniculus	70.62	0.00e+00	665.00
IUUC-Ola-086531	Oryzias latipes	56.05	9.00e-142	496.00
IUUC-Oga-088388	Otolemur garnettii	76.89	0.00e+00	758.00
IUUC-Oar-089748	Ovis aries	77.15	0.00e+00	754.00
IUUC-Ptr-090616	Pan troglodytes	78.01	0.00e+00	759.00
IUUC-Pan-091769	Papio anubis	77.55	6.00e-160	556.00
IUUC-Pma-094383	Petromyzon marinus	49.71	2.00e-128	452.00
IUUC-Pfo-096801	Poecilia formosa	54.24	2.00e-138	485.00
IUUC-Pab-098139	Pongo abelii	76.80	2.00e-180	624.00
IUUC-Pca-100523	Procavia capensis	67.44	0.00e+00	635.00
IUUC-Pva-102286	Pteropus vampyrus	77.94	0.00e+00	753.00
IUUC-Rno-104831	Rattus norvegicus	74.37	0.00e+00	721.00
IUUC-Sha-107499	Sarcophilus harrisii	79.62	0.00e+00	786.00
IUUC-Sar-113389	Sorex araneus	74.79	0.00e+00	718.00
IUUC-Tgu-116769	Taeniopygia guttata	77.52	0.00e+00	766.00
IUUC-Tru-117674	Takifugu rubripes	49.80	1.00e-134	472.00
IUUC-Tsy-119595	Tarsius syrichta	67.88	3.00e-155	540.00
IUUC-Tni-119850	Tetraodon nigroviridis	54.24	6.00e-138	483.00
IUUC-Tbe-127938	Tupaia belangeri	71.38	3.00e-125	441.00
IUUC-Ttr-128193	Tursiops truncatus	78.07	0.00e+00	664.00
IUUC-Vpa-130275	Vicugna pacos	78.57	0.00e+00	764.00
IUUC-Xtr-131982	Xenopus tropicalis	64.58	4.00e-174	603.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence