iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Rno-105410

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

E3 ubiquitin-protein ligase MARCH7; Membrane-associated RING finger protein 7; Membrane-associated RING-CH protein VII; RING-type E3 ubiquitin transferase MARCH7

Genbank Nucleotide ID

BC083842

Gene Name

March7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000006241.7	ENSRNOT00000085563.1	ENSRNOP00000069062.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	86.46	0.00e+00	934.00	IUUC-Hsa-046883

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Functional Description
(View)

The RING-CH-type zinc finger domain is required for E3 ligase activity.

Protein Sequence
(Fasta)

MESKPSRIPR RISVQPSGSL SARMVSGNRG TSLNDSYHSR DSSFRLDSEY QSASASASAS 60
PYQSTWYSES EITQGARSRS QNQQRDHDSK RPKLSCTNCT STSAGRNIGS GLNTLSDSSW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCCAACGGC GGCGGCCACT TCTGCGCCGC ATCCGGAGGG GCGGCCGCCA TTGTGCTTCG 60
TCGCCGACTT CTCTGCTCGT AGCCCGAGGA CCGAGCCCAG CGAGGAAGGG GGCGGCGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51292--ZF_RING_CH

Pfam

PF12906--RINGv

SMART

SM00744--RINGv

Gene Ontology

GO:0016740--F:transferase activity
GO:0008270--F:zinc ion binding
GO:0042130--P:negative regulation of T cell proliferation
GO:0016567--P:protein ubiquitination
GO:0002643--P:regulation of tolerance induction

KEGG

rno:311059

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003999	Anas platyrhynchos	63.78	2.00e-177	615.00
IUUC-Aca-005296	Anolis carolinensis	60.22	2.00e-150	526.00
IUUC-Ame-011193	Astyanax mexicanus	49.45	1.00e-64	241.00
IUUC-Bta-013333	Bos taurus	81.49	0.00e+00	932.00
IUUC-Bra-017315	Brassica rapa	28.57	5.00e-08	52.40
IUUC-Cja-019610	Callithrix jacchus	85.26	0.00e+00	850.00
IUUC-Cfa-021250	Canis familiaris	85.57	0.00e+00	889.00
IUUC-Cpo-022016	Cavia porcellus	83.61	0.00e+00	775.00
IUUC-Csa-023420	Chlorocebus sabaeus	86.09	0.00e+00	857.00
IUUC-Dre-027865	Danio rerio	49.02	2.00e-60	226.00
IUUC-Dno-030094	Dasypus novemcinctus	84.99	0.00e+00	926.00
IUUC-Dor-030822	Dipodomys ordii	77.99	0.00e+00	872.00
IUUC-Ete-032649	Echinops telfairi	84.96	0.00e+00	924.00
IUUC-Eca-033241	Equus caballus	83.63	0.00e+00	887.00
IUUC-Eeu-035188	Erinaceus europaeus	77.84	3.00e-172	598.00
IUUC-Fca-035415	Felis catus	85.13	0.00e+00	881.00
IUUC-Fal-036666	Ficedula albicollis	56.91	3.00e-170	592.00
IUUC-Gac-041953	Gasterosteus aculeatus	41.37	3.00e-49	189.00
IUUC-Gma-043479	Glycine max	25.64	4.00e-07	49.70
IUUC-Ggo-045544	Gorilla gorilla	85.55	0.00e+00	820.00
IUUC-Hsa-046883	Homo sapiens	85.69	0.00e+00	825.00
IUUC-Itr-047989	Ictidomys tridecemlineatus	85.62	0.00e+00	722.00
IUUC-Lch-050154	Latimeria chalumnae	60.14	8.00e-39	155.00
IUUC-Loc-051840	Lepisosteus oculatus	68.06	2.00e-75	277.00
IUUC-Laf-054541	Loxodonta africana	83.91	0.00e+00	858.00
IUUC-Mcc-054882	Macaca mulatta	85.99	0.00e+00	817.00
IUUC-Mtr-058438	Medicago truncatula	29.41	3.00e-08	53.50
IUUC-Mga-059356	Meleagris gallopavo	61.85	2.00e-168	586.00
IUUC-Mmr-060788	Microcebus murinus	86.13	0.00e+00	882.00
IUUC-Mdo-062794	Monodelphis domestica	76.21	0.00e+00	752.00
IUUC-Mmu-063335	Mus musculus	91.50	0.00e+00	996.00
IUUC-Mpu-066830	Mustela putorius furo	86.30	0.00e+00	889.00
IUUC-Mlu-067138	Myotis lucifugus	83.33	0.00e+00	899.00
IUUC-Nle-069584	Nomascus leucogenys	85.23	0.00e+00	828.00
IUUC-Opr-070434	Ochotona princeps	79.75	4.00e-110	392.00
IUUC-Ont-072653	Oreochromis niloticus	42.90	4.00e-51	196.00
IUUC-Ocu-074137	Oryctolagus cuniculus	85.13	0.00e+00	889.00
IUUC-Oga-088502	Otolemur garnettii	84.38	0.00e+00	867.00
IUUC-Oar-090338	Ovis aries	80.72	0.00e+00	920.00
IUUC-Ptr-090675	Pan troglodytes	85.84	0.00e+00	826.00
IUUC-Pan-092888	Papio anubis	85.84	0.00e+00	816.00
IUUC-Psi-094028	Pelodiscus sinensis	66.57	0.00e+00	637.00
IUUC-Pfo-096417	Poecilia formosa	44.14	7.00e-56	212.00
IUUC-Pab-097652	Pongo abelii	85.84	0.00e+00	823.00
IUUC-Pca-100973	Procavia capensis	75.18	2.00e-120	426.00
IUUC-Pva-103013	Pteropus vampyrus	81.61	0.00e+00	849.00
IUUC-Sha-107373	Sarcophilus harrisii	73.58	0.00e+00	740.00
IUUC-Sar-113462	Sorex araneus	78.00	0.00e+00	827.00
IUUC-Tgu-116487	Taeniopygia guttata	62.87	1.00e-176	613.00
IUUC-Tru-118111	Takifugu rubripes	60.69	2.00e-51	196.00
IUUC-Tni-120549	Tetraodon nigroviridis	60.71	6.00e-49	188.00
IUUC-Tbe-127282	Tupaia belangeri	76.54	0.00e+00	741.00
IUUC-Ttr-129177	Tursiops truncatus	80.15	0.00e+00	837.00
IUUC-Vpa-130101	Vicugna pacos	80.88	0.00e+00	754.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence