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Tag Content
UUCD2 ID IUUC-Dre-028422
UUCD1 version UUC-DaR-00286
Ensembl Protein ID ENSDARP00000006534.6
UniProt Accession E7F0K2; E7F0K2_DANRE
Genbank Protein ID ENSDARP00000006534
Protein Name Ring finger protein 19A, RBR E3 ubiquitin protein ligase
Genbank Nucleotide ID FP236813
Gene Name rnf19a
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000012040.7 ENSDART00000024193.7 ENSDARP00000006534.6
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RBR 6.30e-52 177.0 199 399
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RBR
   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++Cll+++ ++++ +++C+h+ C +Cl+qyl+++i+e++ ++iscp  ec+e++++++i+ +l ++ l+++ye+++l++++ ad++++w
   Q: 199  CPLCLLRHTRDRFPDIMTCHHRSCADCLRQYLRIEISESR-VNISCP--ECSERFNPHDIRMILNDRVLMEKYEEFMLRRWLVADPDCRW 285
           ****************************************.9*****..89*************************************** PP
   S: 91   cpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeek.......eeaeskelleanskkCpkCkvyi 171
           cpapdC ++v++  +a  +k ++ +++cg+efC++Ck+ wH++++C+++++++a++ + +       + ++++ ++++++k+Cp+C +yi
   Q: 286  CPAPDCGYAVIAFGCAscPKITCGRDGCGTEFCYHCKQLWHPNQTCDAARQQRAQSLRLRpfrssslSYSQESGAAADDIKPCPRCAAYI 375
           *************99988999999*********************************9999****9999999****************** PP
   S: 172  ek..negCnhmtCakCkaefCwlC 193
           +k  +++CnhmtCa C++efCwlC
   Q: 376  IKmnDGSCNHMTCAVCGCEFCWLC 399
           *997889***************** PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MKCFYADDLK DQVEIQPGDS KLTRVSQLEL PGSREQLAES SPPCLNTSRS PLKTLSPLPS 60
LSPPSPSSSS SPSLPVDTSQ SFGNHSASFG EMSLHQQQQG SERDLPSAAS SVSLPSVRKT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028422|E3,RBR|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCGCGAGAG TAGAGTTTGA ACTGATATGT GAGAAGCGAG CGAGACGGAT GCCAGTGAGT 60
CAGTACGAGC GAAAGAGCGA GCGGAGGACG GGACACACAG GACGGCCCGA CTTCAGCCCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028422|E3,RBR|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF01485--IBR
SMART

SM00647--IBR
SM00184--RING
Gene Ontology

GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
KEGG dre:557995
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001958 Ailuropoda melanoleuca 72.99 0.00e+00 912.00
IUUC-Apl-003427 Anas platyrhynchos 75.42 0.00e+00 917.00
IUUC-Aca-004252 Anolis carolinensis 75.15 0.00e+00 914.00
IUUC-Ame-011434 Astyanax mexicanus 83.88 0.00e+00 1049.00
IUUC-Bta-013558 Bos taurus 73.35 0.00e+00 916.00
IUUC-Cja-019070 Callithrix jacchus 73.38 0.00e+00 918.00
IUUC-Cfa-020286 Canis familiaris 72.87 0.00e+00 909.00
IUUC-Cpo-022015 Cavia porcellus 74.33 0.00e+00 925.00
IUUC-Csa-023975 Chlorocebus sabaeus 73.91 0.00e+00 907.00
IUUC-Cho-024442 Choloepus hoffmanni 60.84 0.00e+00 724.00
IUUC-Dno-029018 Dasypus novemcinctus 73.65 0.00e+00 894.00
IUUC-Dor-030548 Dipodomys ordii 68.72 2.00e-113 403.00
IUUC-Eca-034249 Equus caballus 73.67 0.00e+00 917.00
IUUC-Eeu-035298 Erinaceus europaeus 82.73 0.00e+00 644.00
IUUC-Fca-035912 Felis catus 72.87 0.00e+00 910.00
IUUC-Fal-037488 Ficedula albicollis 73.76 0.00e+00 884.00
IUUC-Gmo-038893 Gadus morhua 82.87 0.00e+00 799.00
IUUC-Gga-040380 Gallus gallus 75.27 0.00e+00 902.00
IUUC-Gac-041421 Gasterosteus aculeatus 76.27 0.00e+00 839.00
IUUC-Ggo-044893 Gorilla gorilla 73.86 0.00e+00 920.00
IUUC-Hsa-046876 Homo sapiens 73.86 0.00e+00 921.00
IUUC-Itr-048257 Ictidomys tridecemlineatus 73.77 0.00e+00 916.00
IUUC-Lch-049774 Latimeria chalumnae 75.39 0.00e+00 944.00
IUUC-Loc-052040 Lepisosteus oculatus 76.45 0.00e+00 983.00
IUUC-Laf-053874 Loxodonta africana 73.73 0.00e+00 902.00
IUUC-Mcc-054817 Macaca mulatta 70.30 6.00e-59 220.00
IUUC-Mga-060175 Meleagris gallopavo 75.18 0.00e+00 915.00
IUUC-Mmr-060800 Microcebus murinus 74.03 0.00e+00 918.00
IUUC-Mdo-061827 Monodelphis domestica 72.89 0.00e+00 873.00
IUUC-Mmu-064134 Mus musculus 78.39 0.00e+00 895.00
IUUC-Mpu-066076 Mustela putorius furo 73.79 0.00e+00 909.00
IUUC-Mlu-068218 Myotis lucifugus 73.75 0.00e+00 892.00
IUUC-Nle-069707 Nomascus leucogenys 83.80 0.00e+00 846.00
IUUC-Opr-070977 Ochotona princeps 74.09 0.00e+00 934.00
IUUC-Ont-072373 Oreochromis niloticus 76.27 0.00e+00 881.00
IUUC-Oan-073376 Ornithorhynchus anatinus 91.67 1.00e-146 513.00
IUUC-Ocu-074878 Oryctolagus cuniculus 74.58 0.00e+00 909.00
IUUC-Ola-086472 Oryzias latipes 77.66 0.00e+00 871.00
IUUC-Oga-088377 Otolemur garnettii 74.33 0.00e+00 916.00
IUUC-Oar-089540 Ovis aries 73.11 0.00e+00 909.00
IUUC-Ptr-090613 Pan troglodytes 73.86 0.00e+00 921.00
IUUC-Pan-092879 Papio anubis 74.03 0.00e+00 906.00
IUUC-Psi-093201 Pelodiscus sinensis 74.16 0.00e+00 894.00
IUUC-Pma-094620 Petromyzon marinus 69.48 0.00e+00 773.00
IUUC-Pfo-096615 Poecilia formosa 76.31 0.00e+00 851.00
IUUC-Pca-100625 Procavia capensis 73.53 0.00e+00 894.00
IUUC-Rno-105998 Rattus norvegicus 74.40 0.00e+00 904.00
IUUC-Sha-107523 Sarcophilus harrisii 82.31 0.00e+00 817.00
IUUC-Sar-113089 Sorex araneus 70.46 0.00e+00 686.00
IUUC-Ssc-115471 Sus scrofa 73.65 0.00e+00 897.00
IUUC-Tgu-117080 Taeniopygia guttata 74.58 0.00e+00 900.00
IUUC-Tru-117547 Takifugu rubripes 78.78 0.00e+00 842.00
IUUC-Tsy-119143 Tarsius syrichta 72.12 0.00e+00 899.00
IUUC-Tni-119693 Tetraodon nigroviridis 75.00 0.00e+00 864.00
IUUC-Ttr-129175 Tursiops truncatus 72.75 0.00e+00 901.00
IUUC-Vpa-130594 Vicugna pacos 67.34 0.00e+00 835.00
IUUC-Xtr-132579 Xenopus tropicalis 75.92 0.00e+00 959.00
Created Date 25-Jun-2017

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