iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054337

UUCD1 version

UUC-LoA-00251

Ensembl Protein ID

ENSLAFP00000005889.4

UniProt Accession

G3SZA5; G3SZA5_LOXAF

Protein Name

Uncharacterized protein

Gene Name

RABGEF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000007009.4	ENSLAFT00000007011.4	ENSLAFP00000005889.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/ZnF_A20	1.20e-17	63.9	13	47

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/ZnF_A20

   S: 1    dpskllCkkgCgfYGnpetngyCSkCyreelrrrr 35
           d+s+llCkkgCg+YGn +++g+CSkC+ree++r+r
   Q: 13   DQSELLCKKGCGYYGNSAWQGFCSKCWREEYHRAR 47
           79*******************************86 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSLKSERRGI HVDQSELLCK KGCGYYGNSA WQGFCSKCWR EEYHRARQKQ IQEDWELAER 60
LQREEEEAFA SSQSNQGAQS LTFSKFEEKK TNEKTRKVTT VKKFFSASSR VGSKKEIPEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCCTGA AGTCTGAACG CCGAGGAATT CACGTGGATC AGTCGGAGCT CCTATGCAAG 60
AAAGGATGTG GTTACTATGG CAACTCTGCG TGGCAGGGCT TCTGCTCCAA GTGCTGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003123--VPS9
IPR002653--Znf_A20

PROSITE

PS51205--VPS9
PS51036--ZF_A20

Pfam

PF02204--VPS9
PF01754--zf-A20

SMART

SM00167--VPS9
SM00259--ZnF_A20

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005730--C:nucleolus
GO:0003677--F:DNA binding
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0050728--P:negative regulation of inflammatory response
GO:1900165--P:negative regulation of interleukin-6 secretion
GO:1900235--P:negative regulation of Kit signaling pathway
GO:0002686--P:negative regulation of leukocyte migration
GO:0043305--P:negative regulation of mast cell degranulation
GO:0001933--P:negative regulation of protein phosphorylation
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0048261--P:negative regulation of receptor-mediated endocytosis
GO:0006612--P:protein targeting to membrane
GO:0060368--P:regulation of Fc receptor mediated stimulatory signaling pathway

KEGG

lav:100665060

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000198	Aegilops tauschii	29.96	4.00e-19	89.70
IUUC-Aml-001771	Ailuropoda melanoleuca	85.14	0.00e+00	726.00
IUUC-Atr-003154	Amborella trichopoda	35.39	4.00e-22	99.00
IUUC-Apl-004018	Anas platyrhynchos	89.63	0.00e+00	845.00
IUUC-Aca-005227	Anolis carolinensis	22.96	2.00e-08	54.30
IUUC-Aly-006138	Arabidopsis lyrata	34.39	2.00e-24	106.00
IUUC-Ath-006929	Arabidopsis thaliana	31.82	3.00e-25	109.00
IUUC-Ago-007776	Ashbya gossypii	29.17	5.00e-23	102.00
IUUC-Acl-008235	Aspergillus clavatus	30.42	5.00e-28	119.00
IUUC-Afl-008570	Aspergillus flavus	32.00	4.00e-31	129.00
IUUC-Afu-008815	Aspergillus fumigatus	30.42	2.00e-28	120.00
IUUC-Ani-009381	Aspergillus nidulans	30.24	2.00e-29	124.00
IUUC-Ang-009615	Aspergillus niger	30.82	2.00e-31	130.00
IUUC-Aor-010195	Aspergillus oryzae	32.00	2.00e-31	130.00
IUUC-Ate-010514	Aspergillus terreus	31.82	3.00e-30	127.00
IUUC-Ame-011365	Astyanax mexicanus	65.35	0.00e+00	661.00
IUUC-Bgr-012102	Blumeria graminis	29.54	3.00e-29	123.00
IUUC-Bta-013124	Bos taurus	95.11	0.00e+00	867.00
IUUC-Bci-013943	Botrytis cinerea	29.93	3.00e-29	123.00
IUUC-Bdi-014539	Brachypodium distachyon	36.11	1.00e-24	107.00
IUUC-Bol-016580	Brassica oleracea	34.40	6.00e-29	121.00
IUUC-Bra-017843	Brassica rapa	33.94	1.00e-28	120.00
IUUC-Cel-018199	Caenorhabditis elegans	34.10	9.00e-59	221.00
IUUC-Cja-019941	Callithrix jacchus	94.30	0.00e+00	861.00
IUUC-Cfa-020845	Canis familiaris	94.78	0.00e+00	791.00
IUUC-Cpo-022037	Cavia porcellus	94.50	0.00e+00	860.00
IUUC-Cre-022696	Chlamydomonas reinhardtii	31.47	5.00e-20	92.40
IUUC-Csa-023272	Chlorocebus sabaeus	93.89	0.00e+00	860.00
IUUC-Cho-025076	Choloepus hoffmanni	83.91	0.00e+00	734.00
IUUC-Cin-025400	Ciona intestinalis	45.62	1.00e-117	416.00
IUUC-Csv-025941	Ciona savignyi	38.07	1.00e-87	317.00
IUUC-Cgl-026725	Colletotrichum gloeosporioides	28.93	8.00e-27	115.00
IUUC-Cne-027057	Cryptococcus neoformans	31.42	2.00e-33	137.00
IUUC-Dre-028484	Danio rerio	70.50	0.00e+00	668.00
IUUC-Dno-028906	Dasypus novemcinctus	94.72	0.00e+00	849.00
IUUC-Dor-030124	Dipodomys ordii	84.69	0.00e+00	739.00
IUUC-Dse-031437	Dothistroma septosporum	28.52	4.00e-26	113.00
IUUC-Dme-031696	Drosophila melanogaster	32.43	8.00e-67	248.00
IUUC-Ete-032573	Echinops telfairi	91.96	0.00e+00	716.00
IUUC-Eca-033711	Equus caballus	95.32	0.00e+00	879.00
IUUC-Eeu-034459	Erinaceus europaeus	72.33	1.00e-76	281.00
IUUC-Fca-035447	Felis catus	92.87	0.00e+00	884.00
IUUC-Fal-036605	Ficedula albicollis	86.04	0.00e+00	783.00
IUUC-Fox-037967	Fusarium oxysporum	26.55	3.00e-18	87.00
IUUC-Fso-038110	Fusarium solani	29.83	1.00e-28	121.00
IUUC-Gmo-038785	Gadus morhua	66.01	0.00e+00	672.00
IUUC-Ggr-039760	Gaeumannomyces graminis	30.55	9.00e-27	115.00
IUUC-Gga-040584	Gallus gallus	90.04	0.00e+00	847.00
IUUC-Gac-042317	Gasterosteus aculeatus	62.85	2.00e-163	568.00
IUUC-Gma-044237	Glycine max	36.87	2.00e-25	110.00
IUUC-Ggo-044498	Gorilla gorilla	80.49	0.00e+00	707.00
IUUC-Hsa-046625	Homo sapiens	94.30	0.00e+00	862.00
IUUC-Hvu-047155	Hordeum vulgare	32.56	4.00e-25	109.00
IUUC-Itr-048753	Ictidomys tridecemlineatus	95.11	0.00e+00	873.00
IUUC-Kpa-049160	Komagataella pastoris	29.39	7.00e-25	108.00
IUUC-Lch-050529	Latimeria chalumnae	78.50	0.00e+00	865.00
IUUC-Lpe-051024	Leersia perrieri	30.54	6.00e-27	115.00
IUUC-Loc-052644	Lepisosteus oculatus	70.02	0.00e+00	665.00
IUUC-Lma-053102	Leptosphaeria maculans	31.62	4.00e-27	116.00
IUUC-Mcc-055659	Macaca mulatta	93.39	5.00e-173	600.00
IUUC-Meu-056084	Macropus eugenii	75.11	2.00e-93	336.00
IUUC-Mor-057255	Magnaporthe oryzae	29.45	2.00e-26	114.00
IUUC-Mpo-057454	Magnaporthe poae	30.55	9.00e-29	121.00
IUUC-Mtr-058098	Medicago truncatula	34.09	2.00e-29	123.00
IUUC-Mla-059068	Melampsora laricipopulina	32.21	1.00e-30	127.00
IUUC-Mga-059624	Meleagris gallopavo	76.78	0.00e+00	837.00
IUUC-Mvi-060282	Microbotryum violaceum	28.53	2.00e-25	111.00
IUUC-Mmr-061142	Microcebus murinus	95.93	0.00e+00	899.00
IUUC-Mdo-062289	Monodelphis domestica	91.45	0.00e+00	892.00
IUUC-Mmu-063961	Mus musculus	94.09	0.00e+00	858.00
IUUC-Mac-065188	Musa acuminata	32.68	1.00e-22	100.00
IUUC-Mpu-066291	Mustela putorius furo	94.51	0.00e+00	860.00
IUUC-Mlu-067431	Myotis lucifugus	90.45	0.00e+00	837.00
IUUC-Nfi-068422	Neosartorya fischeri	30.33	2.00e-29	124.00
IUUC-Ncr-068843	Neurospora crassa	29.54	2.00e-28	120.00
IUUC-Nle-069079	Nomascus leucogenys	94.50	0.00e+00	863.00
IUUC-Opr-070790	Ochotona princeps	94.44	6.00e-57	215.00
IUUC-Ont-071789	Oreochromis niloticus	69.39	2.00e-179	621.00
IUUC-Oan-072946	Ornithorhynchus anatinus	90.06	0.00e+00	828.00
IUUC-Ocu-073816	Oryctolagus cuniculus	95.33	0.00e+00	862.00
IUUC-Oba-075738	Oryza barthii	31.46	4.00e-16	79.30
IUUC-Obr-076355	Oryza brachyantha	36.26	4.00e-26	112.00
IUUC-Ogl-077592	Oryza glaberrima	28.74	1.00e-27	117.00
IUUC-Ogu-078197	Oryza glumaepatula	28.74	2.00e-27	116.00
IUUC-Oin-079629	Oryza indica	28.74	1.00e-27	117.00
IUUC-Olo-080317	Oryza longistaminata	28.74	2.00e-27	115.00
IUUC-Ome-081589	Oryza meridionalis	35.56	9.00e-25	108.00
IUUC-Oni-082700	Oryza nivara	31.46	3.00e-16	79.70
IUUC-Opu-083923	Oryza punctata	33.74	3.00e-21	95.10
IUUC-Oru-084318	Oryza rufipogon	31.46	3.00e-16	79.70
IUUC-Osa-086246	Oryza sativa	37.29	2.00e-06	43.50
IUUC-Ola-086730	Oryzias latipes	56.09	2.00e-149	521.00
IUUC-Olu-087719	Ostreococcus lucimarinus	33.90	2.00e-22	99.80
IUUC-Oga-088992	Otolemur garnettii	82.92	0.00e+00	884.00
IUUC-Oar-089789	Ovis aries	94.73	0.00e+00	859.00
IUUC-Ptr-091636	Pan troglodytes	94.30	0.00e+00	860.00
IUUC-Pan-092911	Papio anubis	94.09	0.00e+00	861.00
IUUC-Psi-093194	Pelodiscus sinensis	77.57	0.00e+00	835.00
IUUC-Pma-094212	Petromyzon marinus	49.09	4.00e-118	418.00
IUUC-Pno-094831	Phaeosphaeria nodorum	30.47	8.00e-28	119.00
IUUC-Ppa-095705	Physcomitrella patens	33.16	5.00e-28	119.00
IUUC-Pfo-096694	Poecilia formosa	65.02	3.00e-179	621.00
IUUC-Pab-097706	Pongo abelii	94.09	0.00e+00	859.00
IUUC-Pop-099891	Populus trichocarpa	31.84	5.00e-25	108.00
IUUC-Pca-100879	Procavia capensis	96.71	5.00e-103	367.00
IUUC-Ppe-101334	Prunus persica	30.31	5.00e-26	112.00
IUUC-Pva-103225	Pteropus vampyrus	79.80	0.00e+00	696.00
IUUC-Pgr-103564	Puccinia graminis	30.40	6.00e-30	125.00
IUUC-Ptt-103802	Puccinia triticina	30.23	1.00e-25	110.00
IUUC-Pte-104345	Pyrenophora teres	31.25	9.00e-28	119.00
IUUC-Pyt-104716	Pyrenophora triticirepentis	31.18	1.00e-28	121.00
IUUC-Rno-106101	Rattus norvegicus	93.89	0.00e+00	858.00
IUUC-Sce-106460	Saccharomyces cerevisiae	29.62	1.00e-23	103.00
IUUC-Sha-106919	Sarcophilus harrisii	77.39	0.00e+00	838.00
IUUC-Sja-107880	Schizosaccharomyces japonicus	32.17	1.00e-29	124.00
IUUC-Spo-108087	Schizosaccharomyces pombe	29.69	1.00e-27	117.00
IUUC-Ssl-108614	Sclerotinia sclerotiorum	28.93	4.00e-07	50.40
IUUC-Smo-108740	Selaginella moellendorffii	37.14	5.00e-28	118.00
IUUC-Sit-110678	Setaria italica	36.11	3.00e-25	109.00
IUUC-Sly-111526	Solanum lycopersicum	37.08	7.00e-25	108.00
IUUC-Stu-112494	Solanum tuberosum	37.08	4.00e-25	108.00
IUUC-Sar-112929	Sorex araneus	95.27	3.00e-159	555.00
IUUC-Sbi-114242	Sorghum bicolor	32.16	3.00e-27	115.00
IUUC-Sre-115224	Sporisorium reilianum	31.52	4.00e-29	123.00
IUUC-Ssc-115239	Sus scrofa	94.72	0.00e+00	861.00
IUUC-Tgu-117499	Taeniopygia guttata	87.78	0.00e+00	825.00
IUUC-Tru-118027	Takifugu rubripes	64.14	8.00e-142	496.00
IUUC-Tsy-119462	Tarsius syrichta	94.75	0.00e+00	861.00
IUUC-Tni-120855	Tetraodon nigroviridis	64.74	2.00e-175	608.00
IUUC-Tca-121213	Theobroma cacao	32.57	1.00e-24	107.00
IUUC-Tre-122186	Trichoderma reesei	31.08	8.00e-29	121.00
IUUC-Tvi-122541	Trichoderma virens	30.14	1.00e-28	121.00
IUUC-Tae-123631	Triticum aestivum	33.85	1.00e-26	114.00
IUUC-Tur-126572	Triticum urartu	37.22	4.00e-25	109.00
IUUC-Tme-127023	Tuber melanosporum	32.93	1.00e-31	131.00
IUUC-Tbe-127453	Tupaia belangeri	94.81	0.00e+00	759.00
IUUC-Ttr-128526	Tursiops truncatus	94.91	0.00e+00	864.00
IUUC-Uma-129660	Ustilago maydis	32.56	7.00e-30	126.00
IUUC-Vda-129737	Verticillium dahliae	28.52	1.00e-24	108.00
IUUC-Vpa-130505	Vicugna pacos	88.31	0.00e+00	693.00
IUUC-Vvi-131088	Vitis vinifera	35.96	2.00e-23	103.00
IUUC-Xtr-132799	Xenopus tropicalis	79.88	0.00e+00	754.00
IUUC-Xma-133345	Xiphophorus maculatus	66.01	2.00e-175	608.00
IUUC-Yli-134416	Yarrowia lipolytica	32.48	4.00e-32	132.00
IUUC-Zma-134750	Zea mays	35.56	9.00e-25	107.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence