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Tag Content
UUCD2 ID IUUC-Pab-098632
UUCD1 version UUC-PoA-01057
Ensembl Protein ID ENSPPYP00000022065.1
UniProt Accession H2PTN3; H2PTN3_PONAB
Genbank Protein ID ENSPPYP00000022065
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID ABGA01222784
Gene Name USP20
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000019686.1 ENSPPYT00000022973.1 ENSPPYP00000022065.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.60e-111 372.8 144 683
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tG+kNlgN+CYmN++LQ+Lsn+p+l++++le     +    ++++k +l+ks+qkl++e+w k++ ++v p++l + +k ++++f+gy+
   Q: 144  TGMKNLGNSCYMNAALQALSNCPPLTQFFLE-----CGGLVRTDKKPALCKSYQKLVSEVWhKKRPSYVVPTSLSHGIKLVNPMFRGYA 227
           7******************************.....999999*******************99999*********************** PP
   S: 89   qqDaqEflaflldqleeelkk.............eknkpkeeeeeedkselsde................................... 129
           qqD+qEfl++l+dql+eelk+             +++++++e++e d+s ++de                                   
   Q: 228  QQDTQEFLRCLMDQLHEELKEpvvatvalteardSDSSDTDEKREGDRSPSEDEflscdsssdrgegdgqgrgggssqaetellipdea 316
           *******************99886666665555555555555555555555555*********************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 317  sraisekermkdrkfswgqqrtnseqvdedadvdttmaalddqpaeaqppsprssspcrtpepdndahlcsssrpcspvhhheghakls 405
           ***************************************************************************************** PP
   S: 130  ..........................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke....... 185
                                     ++++k+++++s+isd+F+g++ s ++cl+cd+vs++ e+f+dlslp+pgke+ +k+       
   Q: 406  ssppraspvrmapsyvlkkaqvlsagSRRRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPIPGKEDLAKLhsaiyqn 494
           *****************************************************************************99888******* PP
   S: 186  ..........................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLil 232
                                                     +l+dcL++f++++el+g+n+y+ce+ckk+++ +k +k+ +lPe+L++
   Q: 495  vpakpgtcgdsyaaqgwlafiveyirrfvvsctpswfwgpvvTLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCI 583
           ***************************************************************************************** PP
   S: 233  hLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevke 319
           hLkRf  ++e + + kin++v+fple Ldl+pf+++++++q   ++Y+L++v++H+G+++sGHY+ay++n  +g+W++fdD++Vtev+e
   Q: 584  HLKRF--RHEVMYSFKINSHVSFPLEgLDLRPFLAKECTSQ--ITTYDLLSVICHHGTAGSGHYIAYCQNvINGQWYEFDDQYVTEVHE 668
           *****..9999***************************999..9**************************78999************** PP
   S: 320  eevleetgstaYvlfYkr 337
           + v++   +++YvlfY++
   Q: 669  TVVQN---AEGYVLFYRK 683
           *****...********98 PP
   
Organism Pongo abelii
Protein Sequence
(Fasta)
MGDSRDLCPH LDSIGEVTKE DLLLKSKGTC QSCGVTGPNL WACLQVACPY VGCGESFADH 60
STIHAQAKKH NLTVNLTTFR LWCYACEKEV FLEQRLAAPL LGSSKFSEQD SPPPSHPLKA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pab-098632|DUB,USP|Pongo abelii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TGAAATGCTC TGGTTCCTCC CCCAGGCTCC TTGCCAGAGG CCTCCACTCA CTCCAGACCC 60
CTGTAGCCCA TCGCTGTCAG GTGTCAACGA AAGATGCGAA TGCTGGCCGC TCCCTGTGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pab-098632|DUB,USP|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF06337--DUSP
PF00443--UCH
PF02148--zf-UBP
SMART

SM00695--DUSP
SM00290--ZnF_UBP
Gene Ontology

GO:0005813--C:centrosome
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002209 Ailuropoda melanoleuca 92.90 0.00e+00 1655.00
IUUC-Apl-003351 Anas platyrhynchos 86.18 0.00e+00 1556.00
IUUC-Aca-005077 Anolis carolinensis 76.49 0.00e+00 1115.00
IUUC-Ame-011777 Astyanax mexicanus 75.40 0.00e+00 1346.00
IUUC-Bta-013063 Bos taurus 93.55 0.00e+00 1659.00
IUUC-Cja-019868 Callithrix jacchus 96.94 0.00e+00 1760.00
IUUC-Cfa-020761 Canis familiaris 93.77 0.00e+00 1681.00
IUUC-Cpo-022267 Cavia porcellus 86.57 0.00e+00 1555.00
IUUC-Csa-024251 Chlorocebus sabaeus 98.47 0.00e+00 1782.00
IUUC-Cho-024483 Choloepus hoffmanni 95.75 2.00e-123 436.00
IUUC-Csv-025889 Ciona savignyi 43.71 2.00e-35 140.00
IUUC-Dre-028061 Danio rerio 74.44 0.00e+00 1221.00
IUUC-Dno-029423 Dasypus novemcinctus 95.30 0.00e+00 1710.00
IUUC-Dor-030877 Dipodomys ordii 91.17 0.00e+00 1087.00
IUUC-Dme-031837 Drosophila melanogaster 49.02 5.00e-137 481.00
IUUC-Ete-032802 Echinops telfairi 81.43 2.00e-133 470.00
IUUC-Eca-034283 Equus caballus 93.01 0.00e+00 1653.00
IUUC-Eeu-034620 Erinaceus europaeus 90.50 0.00e+00 1177.00
IUUC-Fca-036357 Felis catus 94.10 0.00e+00 1665.00
IUUC-Fal-037411 Ficedula albicollis 86.06 0.00e+00 1556.00
IUUC-Gga-041101 Gallus gallus 85.98 0.00e+00 1538.00
IUUC-Gac-041315 Gasterosteus aculeatus 73.85 0.00e+00 1322.00
IUUC-Ggo-045600 Gorilla gorilla 98.48 0.00e+00 1747.00
IUUC-Hsa-045825 Homo sapiens 99.12 0.00e+00 1763.00
IUUC-Itr-048549 Ictidomys tridecemlineatus 82.20 0.00e+00 1408.00
IUUC-Lch-050002 Latimeria chalumnae 75.62 0.00e+00 1322.00
IUUC-Loc-052574 Lepisosteus oculatus 77.67 0.00e+00 1415.00
IUUC-Laf-054428 Loxodonta africana 93.57 0.00e+00 1665.00
IUUC-Mcc-055736 Macaca mulatta 98.25 0.00e+00 1777.00
IUUC-Mga-059781 Meleagris gallopavo 85.45 0.00e+00 1535.00
IUUC-Mdo-063048 Monodelphis domestica 87.24 0.00e+00 1529.00
IUUC-Mmu-064079 Mus musculus 92.03 0.00e+00 1630.00
IUUC-Mpu-066616 Mustela putorius furo 92.58 0.00e+00 1697.00
IUUC-Mlu-067294 Myotis lucifugus 91.48 0.00e+00 1604.00
IUUC-Nle-070015 Nomascus leucogenys 98.69 0.00e+00 1718.00
IUUC-Opr-070328 Ochotona princeps 92.90 0.00e+00 1669.00
IUUC-Ont-071464 Oreochromis niloticus 74.29 0.00e+00 1312.00
IUUC-Oan-073259 Ornithorhynchus anatinus 79.25 0.00e+00 1312.00
IUUC-Ocu-074630 Oryctolagus cuniculus 91.04 0.00e+00 1590.00
IUUC-Ola-087240 Oryzias latipes 75.16 0.00e+00 1298.00
IUUC-Oga-088761 Otolemur garnettii 94.09 0.00e+00 1711.00
IUUC-Oar-089490 Ovis aries 88.18 0.00e+00 1490.00
IUUC-Ptr-091662 Pan troglodytes 99.12 0.00e+00 1761.00
IUUC-Pan-092199 Papio anubis 98.03 0.00e+00 1769.00
IUUC-Psi-093726 Pelodiscus sinensis 87.12 0.00e+00 1554.00
IUUC-Pma-094389 Petromyzon marinus 62.33 9.00e-100 356.00
IUUC-Pca-100614 Procavia capensis 86.00 0.00e+00 1286.00
IUUC-Pva-102922 Pteropus vampyrus 92.08 0.00e+00 975.00
IUUC-Rno-105215 Rattus norvegicus 91.69 0.00e+00 1630.00
IUUC-Sce-106176 Saccharomyces cerevisiae 32.60 2.00e-25 111.00
IUUC-Sha-106601 Sarcophilus harrisii 87.34 0.00e+00 1520.00
IUUC-Ssc-115533 Sus scrofa 91.68 0.00e+00 1628.00
IUUC-Tgu-117364 Taeniopygia guttata 86.34 0.00e+00 1531.00
IUUC-Tru-117770 Takifugu rubripes 72.85 0.00e+00 1290.00
IUUC-Tni-120001 Tetraodon nigroviridis 73.23 0.00e+00 1265.00
IUUC-Ttr-128732 Tursiops truncatus 94.10 0.00e+00 1670.00
IUUC-Xtr-132157 Xenopus tropicalis 76.78 0.00e+00 1362.00
Created Date 25-Jun-2017

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