iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-091868

Ensembl Protein ID

ENSPANP00000018063.1

UniProt Accession

A0A096NYA1; A0A096NYA1_PAPAN

Genbank Protein ID

ENSPANP00000018063

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01078068

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000008372.1	ENSPANT00000012677.1	ENSPANP00000018063.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-29	99.8	554	583
UBD/Beta-Prp	6.70e-46	156.9	333	618

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 8    claf.sd.tllvsGsdDgtikvWDlrtgvll 36
           ++ f +d  + ++Gs+Dg++++WD++tg+l+
   Q: 554  AV-FsPDrSYALAGSYDGVLYIWDVDTGKLE 583
           33.599999*******************986 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v f p++sllatg++d+ i +w+v    l   ++l+g  + +t+v+f+p+g   + +   +++++w +   +   tl+gh
   Q: 333  DAHLSEVNAVRFGPNSSLLATGGADRLIHLWNVVGSRLevNQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSGH 421
           789999****************************9999888999****************888888889******************** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl   +c++ t ++ +    c  v + + +++sG++D+++r+Wd++   + +      +++
   Q: 422  KDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSR-TINVLS---YCNDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIP--VQGR 504
           ************************************9.666655...4555555556*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgec.....vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sls+++++ +l+s+s+d+t+k+ dl+ +++      + +++ +d++k   fsp+  + + gs Dg+++iWd+++g+l + lq+++ +
   Q: 505  VTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIrqvfrADGFKCGSDWTK-AVFSPDRSYALAGSYDGVLYIWDVDTGKLESRLQGPHCT 592
           ****************************888833334444555556666.8899*********************************77 PP
   S: 267  visvavlsfgdnvlvlgsedskvniw 292
            +   +++++++++v++++  kv +w
   Q: 593  AVNAVAWCYSGSHVVSVDQGRKVVLW 618
           7777778************99**999 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MAGPGVPGAP VARWKRHIVW QLRLRDRTQK ALFLELVPAY NHLLEKAELL DKFSKKLQPE 60
PNSVTPTTHQ GPWEESGLDS DQVPSLATLR VKWQEEEEGL RLVCGEMAYQ VVEKSVALGA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGGGC CCGGCGTCCC CGGCGCCCCC GTAGCCCGAT GGAAACGCCA CATTGTGTGG 60
CAGCTGCGTC TTCGGGACCG TACGCAAAAG GCGCTCTTCC TGGAGCTGGT GCCGGCCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	69.87	0.00e+00	788.00
IUUC-Atr-003073	Amborella trichopoda	31.42	4.00e-27	115.00
IUUC-Ame-011152	Astyanax mexicanus	41.71	8.00e-120	424.00
IUUC-Bta-013118	Bos taurus	85.14	0.00e+00	948.00
IUUC-Cja-020002	Callithrix jacchus	90.32	0.00e+00	1013.00
IUUC-Cfa-020878	Canis familiaris	82.87	0.00e+00	937.00
IUUC-Cpo-022476	Cavia porcellus	83.28	0.00e+00	929.00
IUUC-Csa-024134	Chlorocebus sabaeus	97.91	0.00e+00	1095.00
IUUC-Cho-024853	Choloepus hoffmanni	71.21	0.00e+00	643.00
IUUC-Dre-027949	Danio rerio	42.05	2.00e-130	459.00
IUUC-Dno-029683	Dasypus novemcinctus	84.88	0.00e+00	800.00
IUUC-Dor-030897	Dipodomys ordii	77.99	0.00e+00	936.00
IUUC-Ete-032957	Echinops telfairi	92.83	4.00e-131	461.00
IUUC-Eca-033303	Equus caballus	89.81	1.00e-163	568.00
IUUC-Eeu-035336	Erinaceus europaeus	73.70	6.00e-153	534.00
IUUC-Fca-036232	Felis catus	85.81	0.00e+00	1012.00
IUUC-Gmo-038880	Gadus morhua	50.35	4.00e-71	262.00
IUUC-Ggo-045130	Gorilla gorilla	97.27	0.00e+00	739.00
IUUC-Hsa-046359	Homo sapiens	95.88	0.00e+00	1015.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	86.39	0.00e+00	979.00
IUUC-Lch-050669	Latimeria chalumnae	54.52	6.00e-96	343.00
IUUC-Loc-052789	Lepisosteus oculatus	43.34	7.00e-117	414.00
IUUC-Laf-053699	Loxodonta africana	84.96	0.00e+00	945.00
IUUC-Mcc-055657	Macaca mulatta	93.05	0.00e+00	981.00
IUUC-Meu-056639	Macropus eugenii	49.22	2.00e-113	402.00
IUUC-Mmr-061314	Microcebus murinus	80.55	0.00e+00	861.00
IUUC-Mdo-061841	Monodelphis domestica	63.55	0.00e+00	706.00
IUUC-Mmu-064065	Mus musculus	82.87	0.00e+00	949.00
IUUC-Mpu-066742	Mustela putorius furo	83.84	0.00e+00	914.00
IUUC-Mlu-067019	Myotis lucifugus	88.34	0.00e+00	681.00
IUUC-Nle-069037	Nomascus leucogenys	96.05	0.00e+00	1067.00
IUUC-Opr-071039	Ochotona princeps	81.42	0.00e+00	906.00
IUUC-Oan-073431	Ornithorhynchus anatinus	71.60	1.00e-138	486.00
IUUC-Ocu-074772	Oryctolagus cuniculus	84.42	0.00e+00	846.00
IUUC-Ola-086964	Oryzias latipes	52.96	3.00e-83	301.00
IUUC-Oga-088188	Otolemur garnettii	86.27	0.00e+00	926.00
IUUC-Oar-090231	Ovis aries	79.38	0.00e+00	922.00
IUUC-Ptr-091434	Pan troglodytes	93.57	0.00e+00	971.00
IUUC-Psi-093652	Pelodiscus sinensis	64.04	2.00e-167	581.00
IUUC-Pab-097776	Pongo abelii	94.73	0.00e+00	979.00
IUUC-Pca-100220	Procavia capensis	65.59	0.00e+00	629.00
IUUC-Pva-103135	Pteropus vampyrus	86.66	0.00e+00	886.00
IUUC-Rno-105529	Rattus norvegicus	81.38	0.00e+00	982.00
IUUC-Sha-107062	Sarcophilus harrisii	64.01	0.00e+00	736.00
IUUC-Sar-113109	Sorex araneus	66.75	3.00e-136	478.00
IUUC-Ssc-115271	Sus scrofa	86.15	0.00e+00	927.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence