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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-045907
Ensembl Protein ID ENSP00000434513.1
UniProt Accession Q32P44; Q6ZQW7; Q8NA55; EMAL3_HUMAN
Genbank Protein ID BAC04073.1; BAC87566.1; AAI08281.1
Protein Name Echinoderm microtubule-associated protein-like 3
Genbank Nucleotide ID AK093146; AK128679; BC108280
Gene Name EML3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000149499.11 ENST00000439994.5 ENSP00000409611.1
ENSG00000149499.11 ENST00000394773.6 ENSP00000378254.2
ENSG00000149499.11 ENST00000394776.8 ENSP00000378256.4
ENSG00000149499.11 ENST00000278845.8 ENSP00000278845.4
ENSG00000149499.11 ENST00000529309.5 ENSP00000434513.1
ENSG00000149499.11 ENST00000494448.5 ENSP00000431752.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICHPM
DNA & RNA Element
UTRdbcircBaseCircNetmiRTarBase
microRNATRANSFACRepTarSomamiR
miRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProtPHOSIDA
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.20e-14 54.7 595 625
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gHtd+ ++l+  ++ ++++++++D ++ +WD
   Q: 595  GHTDELWGLCThPSqNRFLTCGHDRQLCLWD 625
           8********989777**************** PP
   
Organism Homo sapiens
Functional Description
(View)

Functional Description


     May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
 May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
Protein Sequence
(Fasta)
MDGAAGPGDG PAREALQSLS QRLRVQEQEM ELVKAALAEA LRLLRLQVPP SSLQGSGTPA 60
PPGDSLAAPP GLPPTCTPSL VSRGTQTETE VELKSSPGPP GLSNGPPAPQ GASEEPSGTQ 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045907|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCTCCGCGT CCGGCGCCTG TTTGTGCTGC GGCGCTGTGG CACCGGACGG CCCTGCCACC 60
CCACCCCCGG GAGCCGAGAG CGGCCCCGGG AGAGTCCGAG GGCCCGGGGG GGTCTGGAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045907|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF03451--HELP
PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005874--C:microtubule
GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding
KEGG hsa:256364
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002054 Ailuropoda melanoleuca 86.72 0.00e+00 1229.00
IUUC-Bta-012809 Bos taurus 92.99 0.00e+00 1198.00
IUUC-Cja-019497 Callithrix jacchus 99.35 0.00e+00 1313.00
IUUC-Cfa-020836 Canis familiaris 91.58 0.00e+00 1194.00
IUUC-Cpo-021285 Cavia porcellus 88.42 0.00e+00 1176.00
IUUC-Csa-023442 Chlorocebus sabaeus 98.96 0.00e+00 1306.00
IUUC-Cho-024509 Choloepus hoffmanni 88.40 1.00e-127 450.00
IUUC-Dno-029179 Dasypus novemcinctus 90.52 0.00e+00 1201.00
IUUC-Dor-030271 Dipodomys ordii 92.16 0.00e+00 1195.00
IUUC-Ete-033095 Echinops telfairi 83.44 0.00e+00 730.00
IUUC-Eca-033995 Equus caballus 94.74 0.00e+00 1233.00
IUUC-Eeu-034661 Erinaceus europaeus 88.02 2.00e-145 509.00
IUUC-Fca-036507 Felis catus 92.85 0.00e+00 1235.00
IUUC-Ggo-044578 Gorilla gorilla 99.83 0.00e+00 1137.00
IUUC-Itr-047963 Ictidomys tridecemlineatus 94.02 0.00e+00 1250.00
IUUC-Laf-054051 Loxodonta africana 92.70 0.00e+00 1311.00
IUUC-Mcc-055534 Macaca mulatta 98.68 0.00e+00 1402.00
IUUC-Meu-056318 Macropus eugenii 87.06 0.00e+00 994.00
IUUC-Mmr-060972 Microcebus murinus 90.27 0.00e+00 1339.00
IUUC-Mdo-062421 Monodelphis domestica 87.64 0.00e+00 1090.00
IUUC-Mmu-064240 Mus musculus 93.13 0.00e+00 1217.00
IUUC-Mpu-065950 Mustela putorius furo 94.16 0.00e+00 1211.00
IUUC-Mlu-067823 Myotis lucifugus 89.68 0.00e+00 1159.00
IUUC-Nle-069939 Nomascus leucogenys 98.57 0.00e+00 1300.00
IUUC-Opr-070593 Ochotona princeps 96.08 0.00e+00 1104.00
IUUC-Oan-073228 Ornithorhynchus anatinus 90.79 0.00e+00 1033.00
IUUC-Ocu-074660 Oryctolagus cuniculus 93.21 0.00e+00 1203.00
IUUC-Oga-088749 Otolemur garnettii 92.92 0.00e+00 1367.00
IUUC-Oar-090190 Ovis aries 92.21 0.00e+00 1231.00
IUUC-Pan-091858 Papio anubis 98.83 0.00e+00 1310.00
IUUC-Pab-098492 Pongo abelii 99.74 0.00e+00 1282.00
IUUC-Pca-100221 Procavia capensis 83.99 0.00e+00 1157.00
IUUC-Pva-103024 Pteropus vampyrus 92.64 0.00e+00 1199.00
IUUC-Rno-105563 Rattus norvegicus 92.74 0.00e+00 1293.00
IUUC-Sha-106886 Sarcophilus harrisii 90.22 0.00e+00 1040.00
IUUC-Ssc-116107 Sus scrofa 94.29 0.00e+00 1212.00
Created Date 25-Jun-2017

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