iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004916

UUCD1 version

UUC-AnC-00866

Ensembl Protein ID

ENSACAP00000017276.2

UniProt Accession

G1KU39; G1KU39_ANOCA

Protein Name

Uncharacterized protein

Gene Name

RNF222

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000017555.2	ENSACAT00000017616.2	ENSACAP00000017276.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.40e-08	33.5	13	64

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplv....lpCgHvfhadCl.qkw..pglknssskefrCPlCr 46
           C++C+e+f+  p+v    l+CgH+f++dCl +++         +++ +CP+Cr
   Q: 13   CPVCYEPFQS-PKVsrrmLSCGHTFCHDCLvKCLlvSRDEGRLQNTLTCPVCR 64
           ********88.776344477**********75558755556689999*****8 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

PSKDGSTTTS SECPVCYEPF QSPKVSRRML SCGHTFCHDC LVKCLLVSRD EGRLQNTLTC 60
PVCRFVTFLC RKRARWLPKS ALNPPALELP LSPSSLPCGV TLSPSNTLVV PGHFLAPFHG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCAGCAAAG ATGGTTCTAC CACCACCTCA TCAGAATGCC CTGTGTGTTA CGAGCCGTTT 60
CAGTCTCCAA AGGTCTCACG TCGGATGCTG AGCTGTGGGC ACACCTTTTG CCATGACTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0033768--C:SUMO-targeted ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0033234--P:negative regulation of protein sumoylation
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001331	Ailuropoda melanoleuca	60.94	9.00e-21	92.00
IUUC-Apl-003509	Anas platyrhynchos	48.79	1.00e-42	166.00
IUUC-Bta-013443	Bos taurus	43.62	2.00e-21	95.50
IUUC-Cja-019637	Callithrix jacchus	37.74	2.00e-23	101.00
IUUC-Cfa-020737	Canis familiaris	41.61	3.00e-24	104.00
IUUC-Cpo-022224	Cavia porcellus	38.93	9.00e-22	96.30
IUUC-Csa-024175	Chlorocebus sabaeus	40.52	3.00e-25	108.00
IUUC-Dre-028060	Danio rerio	30.77	9.00e-17	79.70
IUUC-Dno-030024	Dasypus novemcinctus	41.06	3.00e-22	97.80
IUUC-Dor-030936	Dipodomys ordii	41.89	2.00e-24	105.00
IUUC-Eca-033759	Equus caballus	39.10	1.00e-26	112.00
IUUC-Fal-037142	Ficedula albicollis	46.34	4.00e-36	144.00
IUUC-Gmo-039196	Gadus morhua	32.68	4.00e-14	71.20
IUUC-Gga-041189	Gallus gallus	46.82	4.00e-38	150.00
IUUC-Gac-041497	Gasterosteus aculeatus	38.95	2.00e-16	78.20
IUUC-Ggo-045020	Gorilla gorilla	41.18	1.00e-25	108.00
IUUC-Hsa-046317	Homo sapiens	39.07	3.00e-23	101.00
IUUC-Itr-048656	Ictidomys tridecemlineatus	39.46	5.00e-25	107.00
IUUC-Lch-049885	Latimeria chalumnae	46.74	4.00e-19	87.80
IUUC-Laf-053457	Loxodonta africana	43.62	6.00e-27	113.00
IUUC-Mcc-054653	Macaca mulatta	39.35	5.00e-24	103.00
IUUC-Mga-059753	Meleagris gallopavo	46.07	1.00e-37	149.00
IUUC-Mdo-062993	Monodelphis domestica	36.70	6.00e-28	117.00
IUUC-Mmu-063225	Mus musculus	39.46	7.00e-24	103.00
IUUC-Mpu-066299	Mustela putorius furo	41.50	4.00e-24	104.00
IUUC-Mlu-066988	Myotis lucifugus	41.33	2.00e-22	98.60
IUUC-Nle-069011	Nomascus leucogenys	39.87	2.00e-24	105.00
IUUC-Opr-070258	Ochotona princeps	41.29	4.00e-22	97.40
IUUC-Ont-071886	Oreochromis niloticus	32.34	7.00e-17	80.10
IUUC-Ocu-074282	Oryctolagus cuniculus	41.33	2.00e-23	102.00
IUUC-Oga-088403	Otolemur garnettii	41.06	2.00e-23	101.00
IUUC-Oar-089665	Ovis aries	57.14	5.00e-11	58.50
IUUC-Ptr-090580	Pan troglodytes	39.07	3.00e-23	101.00
IUUC-Pan-092447	Papio anubis	40.00	1.00e-24	105.00
IUUC-Psi-093673	Pelodiscus sinensis	52.40	4.00e-55	207.00
IUUC-Pfo-096933	Poecilia formosa	35.12	4.00e-18	84.30
IUUC-Pab-097867	Pongo abelii	39.07	4.00e-23	100.00
IUUC-Pva-102146	Pteropus vampyrus	40.14	4.00e-24	104.00
IUUC-Rno-105897	Rattus norvegicus	40.27	3.00e-24	104.00
IUUC-Sha-107282	Sarcophilus harrisii	39.32	2.00e-27	115.00
IUUC-Sar-113260	Sorex araneus	40.27	7.00e-25	106.00
IUUC-Ssc-115449	Sus scrofa	40.27	5.00e-21	94.00
IUUC-Tgu-117349	Taeniopygia guttata	43.85	2.00e-35	141.00
IUUC-Xtr-132180	Xenopus tropicalis	40.38	4.00e-23	100.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence