iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ola-087366

Ensembl Protein ID

ENSORLP00000018026.1

UniProt Accession

H2MHC1; H2MHC1_ORYLA

Genbank Protein ID

ENSORLP00000018026

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

BAAF04031885

Gene Name

CSK (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000014381.1	ENSORLT00000018027.1	ENSORLP00000018026.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.60e-10	40.4	13	67

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            + + y+++ +n+ +L + kGdv+++i   + d +W ++ ++++g++G +P+n+v+k
   Q: 13   ECVAKYNFQTANEQDLPFCKGDVLTII-GVTRDPNWYRA-RNTTGREGTIPANYVQK 67
           68999**********************.***********.6**************87 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MSGIHAPWTS GTECVAKYNF QTANEQDLPF CKGDVLTIIG VTRDPNWYRA RNTTGREGTI 60
PANYVQKREG VKSGGKLSLM PWFHGKITRE QAERLLYPPE TGLFLVREST NYPGDYTLCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCTCGCAG ACGAGCGCCA CACACGCAAA CATCCACACA TATGCAGTCA GAGTGGAGAC 60
AACCGTCAAC GCAGAGCCAC GTTTGGGATC GTTCGGTATC GACGCTGCAA ACCCCGGACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0060027--P:convergent extension involved in gastrulation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004391	Anolis carolinensis	85.65	0.00e+00	791.00
IUUC-Fal-037215	Ficedula albicollis	87.07	0.00e+00	793.00
IUUC-Gmo-039103	Gadus morhua	94.00	0.00e+00	827.00
IUUC-Loc-052586	Lepisosteus oculatus	93.38	0.00e+00	837.00
IUUC-Meu-056387	Macropus eugenii	84.56	0.00e+00	794.00
IUUC-Mdo-061871	Monodelphis domestica	84.12	0.00e+00	793.00
IUUC-Oga-087928	Otolemur garnettii	85.01	0.00e+00	804.00
IUUC-Sha-106987	Sarcophilus harrisii	84.56	0.00e+00	795.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence