iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021326

Ensembl Protein ID

ENSCPOP00000015556.1

UniProt Accession

H0VXX5; H0VXX5_CAVPO

Genbank Protein ID

ENSCPOP00000015556

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02033268

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000020382.1	ENSCPOT00000022396.1	ENSCPOP00000015556.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.30e-12	47.8	123	182

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk vLaasS ++++l  +        +  +++ d v+p vfr +l+F+Ytg+l
   Q: 123  CDVIIVVQNALFRAHKNVLAASSAYLKSLVVH-------DNLLNLDhDmVSPAVFRLVLDFIYTGRL 182
           9*****************************77.......4566677678****************98 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

AGGRSQPCRT ERRAAARWRH SCSSARLLGP LQIRVCGKRS GAETRPGRGE DGPAGQTDRG 60
PGGRRAAQRS HPPWIRRQPG PGLPTCPPGE CAGQTMLDTM EAPGHSRQLL LQLNNQRTKG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGGAGGGA GGTCGCAGCC CTGCCGCACA GAGCGCCGCG CAGCCGCAAG GTGGCGCCAT 60
AGTTGCAGCA GCGCCCGCCT GCTTGGGCCG CTCCAGATAA GAGTGTGTGG AAAGCGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	88.70	4.00e-150	524.00
IUUC-Aca-004680	Anolis carolinensis	77.01	2.00e-69	256.00
IUUC-Ame-010967	Astyanax mexicanus	60.24	1.00e-92	333.00
IUUC-Bta-013567	Bos taurus	91.86	2.00e-161	563.00
IUUC-Cja-019621	Callithrix jacchus	92.59	3.00e-60	223.00
IUUC-Cfa-020731	Canis familiaris	91.68	0.00e+00	887.00
IUUC-Csa-023645	Chlorocebus sabaeus	92.09	0.00e+00	864.00
IUUC-Dre-028027	Danio rerio	57.31	9.00e-94	338.00
IUUC-Dno-028900	Dasypus novemcinctus	89.56	0.00e+00	914.00
IUUC-Fal-036980	Ficedula albicollis	63.73	5.00e-118	418.00
IUUC-Gga-040708	Gallus gallus	59.51	0.00e+00	653.00
IUUC-Ggo-044591	Gorilla gorilla	93.20	4.00e-138	485.00
IUUC-Hsa-046769	Homo sapiens	92.37	0.00e+00	852.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	92.23	0.00e+00	1023.00
IUUC-Lch-049412	Latimeria chalumnae	55.57	0.00e+00	645.00
IUUC-Loc-051883	Lepisosteus oculatus	63.77	2.00e-97	349.00
IUUC-Laf-053358	Loxodonta africana	89.92	9.00e-165	573.00
IUUC-Mcc-054981	Macaca mulatta	92.02	0.00e+00	848.00
IUUC-Meu-056181	Macropus eugenii	69.92	2.00e-108	385.00
IUUC-Mga-059592	Meleagris gallopavo	74.48	3.00e-107	382.00
IUUC-Mmr-061560	Microcebus murinus	92.72	0.00e+00	855.00
IUUC-Mdo-062511	Monodelphis domestica	81.45	9.00e-91	327.00
IUUC-Mmu-064258	Mus musculus	90.12	0.00e+00	978.00
IUUC-Mpu-065911	Mustela putorius furo	91.60	0.00e+00	872.00
IUUC-Mlu-067575	Myotis lucifugus	76.55	3.00e-133	468.00
IUUC-Ont-072493	Oreochromis niloticus	65.55	7.00e-81	295.00
IUUC-Ola-086584	Oryzias latipes	62.01	5.00e-89	322.00
IUUC-Oga-088774	Otolemur garnettii	90.43	0.00e+00	922.00
IUUC-Ptr-090491	Pan troglodytes	94.40	3.00e-121	428.00
IUUC-Pma-094179	Petromyzon marinus	70.51	4.00e-31	125.00
IUUC-Pfo-096282	Poecilia formosa	57.40	2.00e-88	320.00
IUUC-Pab-098488	Pongo abelii	91.29	5.00e-171	594.00
IUUC-Pca-100667	Procavia capensis	92.61	4.00e-144	505.00
IUUC-Pva-102421	Pteropus vampyrus	92.09	0.00e+00	862.00
IUUC-Rno-105528	Rattus norvegicus	89.47	0.00e+00	822.00
IUUC-Sar-113478	Sorex araneus	98.34	1.00e-118	420.00
IUUC-Ssc-115420	Sus scrofa	92.59	0.00e+00	869.00
IUUC-Tgu-116642	Taeniopygia guttata	60.74	0.00e+00	648.00
IUUC-Tru-118583	Takifugu rubripes	62.06	7.00e-85	308.00
IUUC-Xtr-132210	Xenopus tropicalis	59.58	0.00e+00	674.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence