iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020396

Ensembl Protein ID

ENSCAFP00000001753.3

UniProt Accession

E2RGK6; E2RGK6_CANLF

Genbank Protein ID

ENSCAFP00000001753

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03008256

Gene Name

PACSIN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000001221.3	ENSCAFT00000001902.3	ENSCAFP00000001753.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.90e-15	55.9	389	444

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v++lydy++q++deL++k+Gd ++ +  ee ++gW++g + ++g+ Gl P+n+ve +
   Q: 389  RVRALYDYDGQEQDELSFKAGDELTKL-GEEDEQGWCRG-RLDSGQLGLYPANYVEAI 444
           699************************.***********.59*************975 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MSGSYDEASL APEETTDSFW EVGNYKRTVK RIDDGHRLCN DLMNCVQERA KIEKAYAQQL 60
TDWAKRWRQL IEKGPQYGSL ERAWGAIMTE ADKVSELHQE VKNNLLNEDL EKVKNWQKDA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGGAGAGG AGGGGCCGTC ACTCAGGGCG CGCGCACCCC GTCCACGCAC CCTCTCGTCC 60
CAGAAGACGC AGGGTAGGGG AGGCCAGCAA CCGACAGACG GACGGTCAGA CAGGGCCAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028518--PACSIN1
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0030137--C:COPI-coated vesicle
GO:0005768--C:endosome
GO:0043209--C:myelin sheath
GO:0032587--C:ruffle membrane
GO:0045202--C:synapse
GO:0005543--F:phospholipid binding
GO:0007015--P:actin filament organization
GO:0045806--P:negative regulation of endocytosis
GO:0048812--P:neuron projection morphogenesis
GO:0097320--P:plasma membrane tubulation
GO:0072657--P:protein localization to membrane
GO:0030100--P:regulation of endocytosis
GO:0048488--P:synaptic vesicle endocytosis

KEGG

cfa:608087

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001861	Ailuropoda melanoleuca	90.37	0.00e+00	795.00
IUUC-Apl-003667	Anas platyrhynchos	83.72	0.00e+00	698.00
IUUC-Aca-005229	Anolis carolinensis	81.39	0.00e+00	718.00
IUUC-Ame-011410	Astyanax mexicanus	74.44	2.00e-180	625.00
IUUC-Bta-013509	Bos taurus	95.95	0.00e+00	762.00
IUUC-Cja-019659	Callithrix jacchus	96.85	0.00e+00	827.00
IUUC-Cpo-022376	Cavia porcellus	96.17	0.00e+00	793.00
IUUC-Csa-023701	Chlorocebus sabaeus	97.07	0.00e+00	800.00
IUUC-Dre-027456	Danio rerio	74.94	0.00e+00	676.00
IUUC-Eca-033679	Equus caballus	91.95	0.00e+00	736.00
IUUC-Fca-036314	Felis catus	99.32	0.00e+00	818.00
IUUC-Fal-037300	Ficedula albicollis	84.75	0.00e+00	736.00
IUUC-Gmo-038571	Gadus morhua	68.81	2.00e-163	568.00
IUUC-Gga-040626	Gallus gallus	85.65	0.00e+00	694.00
IUUC-Gac-041445	Gasterosteus aculeatus	69.64	3.00e-168	584.00
IUUC-Ggo-045557	Gorilla gorilla	96.85	0.00e+00	798.00
IUUC-Hsa-045778	Homo sapiens	96.85	0.00e+00	798.00
IUUC-Itr-048856	Ictidomys tridecemlineatus	97.07	0.00e+00	801.00
IUUC-Lch-050070	Latimeria chalumnae	71.69	0.00e+00	672.00
IUUC-Loc-051764	Lepisosteus oculatus	79.64	0.00e+00	697.00
IUUC-Laf-054465	Loxodonta africana	95.96	0.00e+00	807.00
IUUC-Mcc-055324	Macaca mulatta	96.85	0.00e+00	801.00
IUUC-Meu-056348	Macropus eugenii	90.54	0.00e+00	746.00
IUUC-Mga-059285	Meleagris gallopavo	85.68	0.00e+00	680.00
IUUC-Mmr-061367	Microcebus murinus	97.07	0.00e+00	757.00
IUUC-Mdo-062432	Monodelphis domestica	58.17	8.00e-140	489.00
IUUC-Mmu-064347	Mus musculus	95.27	0.00e+00	825.00
IUUC-Mpu-066864	Mustela putorius furo	99.55	0.00e+00	817.00
IUUC-Nle-070027	Nomascus leucogenys	96.70	0.00e+00	754.00
IUUC-Ont-072188	Oreochromis niloticus	72.71	0.00e+00	641.00
IUUC-Ocu-074297	Oryctolagus cuniculus	95.95	0.00e+00	767.00
IUUC-Ola-087188	Oryzias latipes	72.26	9.00e-162	563.00
IUUC-Oga-088856	Otolemur garnettii	97.30	0.00e+00	779.00
IUUC-Oar-090278	Ovis aries	88.06	0.00e+00	657.00
IUUC-Pan-092056	Papio anubis	97.07	0.00e+00	800.00
IUUC-Pfo-097528	Poecilia formosa	70.02	1.00e-157	549.00
IUUC-Pab-098202	Pongo abelii	96.85	0.00e+00	799.00
IUUC-Pca-100881	Procavia capensis	95.72	0.00e+00	786.00
IUUC-Pva-102181	Pteropus vampyrus	97.30	0.00e+00	802.00
IUUC-Rno-105295	Rattus norvegicus	92.34	0.00e+00	768.00
IUUC-Sha-107163	Sarcophilus harrisii	76.87	0.00e+00	660.00
IUUC-Ssc-115685	Sus scrofa	97.07	0.00e+00	800.00
IUUC-Tgu-116524	Taeniopygia guttata	78.03	0.00e+00	649.00
IUUC-Tru-118248	Takifugu rubripes	70.09	4.00e-154	537.00
IUUC-Tni-120717	Tetraodon nigroviridis	70.47	4.00e-158	550.00
IUUC-Ttr-129069	Tursiops truncatus	97.16	0.00e+00	756.00
IUUC-Xtr-132759	Xenopus tropicalis	70.92	0.00e+00	647.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence