iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000008169.1	ENSAMET00000008953.1	ENSAMEP00000008590.1
ENSAMEG00000008169.1	ENSAMET00000008977.1	ENSAMEP00000008613.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-106	356.5	505	1338

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l++++ + ++  +ln++np ++kg+++k++ +l++elw++++k+v+p +l  +++k+a++f+g
   Q: 505  TGLSNLGNTCFMNSSIQCVSNTQPLTQYFISgRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNVAPLKLPWTIAKYAPRFNG 591
           7******************************9******************************************************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a++++ ++n+s+++dlF+gql+sq++c++c+++s+r++p
   Q: 592  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSD--GRPDWevaaeAWDNHLRRNRSIVVDLFHGQLRSQVRCKTCGHISVRFDP 676
           ********************************9999..6666666777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++ +++e                                                                      
   Q: 677  FNFLSLPLPMDSYMHLEitvikldgttpvryglrlnmdekytglkkqlsdlcglkseqillaevhgsniknfpqdnqkvrlsvsgfl 763
           *************9999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 764  cafeipipgspisasspiqtdfssspstngmftlttngdlprpifipngmpntvvpcgteknftngvvnghmpslpdnsftgyiiav 850
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 851  hrkmmrtelyflssqknrpslfgmplivpctvhtrkkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvqkdgns 937
           *************************************************************************************** PP
   S: 186  ...................................................................slqdcLesftkeeelegenk 205
                                                                              +l++cL++ft+eeel ++++
   Q: 938  cawcpwyrfcrgckidcgedrafignayiavdwdptalhlryqtsqervvdehesveqsrraqaepiNLDSCLRAFTSEEELGENEM 1024
           *************************************************************************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts........................ 267
           yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e +d s f++                         
   Q: 1025 YYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQFVNG--RWIKSQKIVKFPREsFDPSAFLVPrdpalcqrkpltpqgddlseprvp 1109
           ********************************99775..5569******************99999999999999999999999999 PP
   S: 268  ....................................................................................... 267
                                                                                                  
   Q: 1110 ggdvkkvdaqnsageedvllskspsslsaniisspkgspsstrksrtscpssknsspnssprtlgrskgrlrlpqigsknklssike 1196
           999999999999999999999999999999999888888888888888887777777777777777777777777777666666666 PP
   S: 268  ...............................................................peekqke................k 275
                                                                          +     +                k
   Q: 1197 nldaskengagqvceladalsrghmlggsqtelvtpqdhevalangflyeheacgngysngqlE-----NhseedstddqredvhvK 1278
           6666666666666666666666666666666666655555555555555555555555555550.....05555555566666667* PP
   S: 276  kkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
            +Y+L+a+ +HsG l++GHYv+y+kn + kW++++Ds+++e++ +e+ +   ++aY+lfY+++
   Q: 1279 PIYNLYAISCHSGILGGGHYVTYAKNPNSKWYCYNDSSCKELHPDEIDT---DSAYILFYEQQ 1338
           *************************************************...********985 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

SYFTGLFNAF DENRDNHIDF KEISCGLSAC CRGPLAERQK FCFKVFDVDR DGVLSRVELR 60
DMVVALSEVW KDNRTDDIPE LHTDLSGIVE GILNAHDTTK MGHLTLEDYQ IWSVKNVLAN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTACAGATG TAGAGCTGAA ACGACTGAAA GATGCCTTTA AAAGGACCTG TGGACTCTCA 60
TACTATATGG GCCAGCACTG CTTCATCAGG GAAGTGCTTG GGGATGGAGT GCCTCCAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003272	Anas platyrhynchos	82.36	0.00e+00	2298.00
IUUC-Aca-005057	Anolis carolinensis	81.99	0.00e+00	1897.00
IUUC-Ame-010781	Astyanax mexicanus	72.80	0.00e+00	2000.00
IUUC-Bta-013502	Bos taurus	93.00	0.00e+00	2514.00
IUUC-Cja-018754	Callithrix jacchus	96.57	0.00e+00	2615.00
IUUC-Cfa-020526	Canis familiaris	98.47	0.00e+00	2659.00
IUUC-Cpo-021568	Cavia porcellus	92.58	0.00e+00	2484.00
IUUC-Csa-023143	Chlorocebus sabaeus	96.57	0.00e+00	2601.00
IUUC-Cho-024603	Choloepus hoffmanni	65.04	7.00e-131	462.00
IUUC-Cin-025583	Ciona intestinalis	51.04	0.00e+00	1075.00
IUUC-Csv-026344	Ciona savignyi	46.76	0.00e+00	966.00
IUUC-Dre-028121	Danio rerio	74.58	0.00e+00	1963.00
IUUC-Dno-029911	Dasypus novemcinctus	95.13	0.00e+00	2595.00
IUUC-Dor-030608	Dipodomys ordii	67.56	0.00e+00	682.00
IUUC-Dme-032094	Drosophila melanogaster	44.83	6.00e-122	432.00
IUUC-Ete-032639	Echinops telfairi	94.41	0.00e+00	1590.00
IUUC-Eca-034253	Equus caballus	97.37	0.00e+00	2649.00
IUUC-Eeu-035084	Erinaceus europaeus	81.00	0.00e+00	1231.00
IUUC-Fca-035474	Felis catus	97.64	0.00e+00	2535.00
IUUC-Fal-036985	Ficedula albicollis	83.65	0.00e+00	2261.00
IUUC-Gmo-039568	Gadus morhua	79.48	0.00e+00	1722.00
IUUC-Gga-040509	Gallus gallus	81.80	0.00e+00	2298.00
IUUC-Gac-041757	Gasterosteus aculeatus	80.24	0.00e+00	1791.00
IUUC-Ggo-044956	Gorilla gorilla	86.15	0.00e+00	1368.00
IUUC-Hsa-046107	Homo sapiens	96.64	0.00e+00	2599.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	95.17	0.00e+00	1192.00
IUUC-Lch-050681	Latimeria chalumnae	75.99	0.00e+00	2046.00
IUUC-Loc-052474	Lepisosteus oculatus	75.86	0.00e+00	2065.00
IUUC-Laf-054273	Loxodonta africana	96.06	0.00e+00	2595.00
IUUC-Mcc-054718	Macaca mulatta	96.43	0.00e+00	2600.00
IUUC-Meu-056558	Macropus eugenii	70.47	0.00e+00	1050.00
IUUC-Mga-059892	Meleagris gallopavo	83.85	0.00e+00	2340.00
IUUC-Mmr-060866	Microcebus murinus	95.52	0.00e+00	2630.00
IUUC-Mdo-062607	Monodelphis domestica	91.55	0.00e+00	2516.00
IUUC-Mmu-063797	Mus musculus	94.60	0.00e+00	2614.00
IUUC-Mpu-066121	Mustela putorius furo	99.27	0.00e+00	2706.00
IUUC-Mlu-067581	Myotis lucifugus	95.57	0.00e+00	2638.00
IUUC-Nle-069916	Nomascus leucogenys	94.46	0.00e+00	2524.00
IUUC-Opr-071073	Ochotona princeps	89.23	0.00e+00	876.00
IUUC-Ont-071310	Oreochromis niloticus	81.03	0.00e+00	1755.00
IUUC-Oan-073356	Ornithorhynchus anatinus	89.73	0.00e+00	2458.00
IUUC-Ocu-074216	Oryctolagus cuniculus	95.48	0.00e+00	2580.00
IUUC-Ola-087434	Oryzias latipes	73.59	0.00e+00	1907.00
IUUC-Oga-089034	Otolemur garnettii	95.78	0.00e+00	2608.00
IUUC-Oar-090369	Ovis aries	97.23	0.00e+00	2694.00
IUUC-Ptr-090605	Pan troglodytes	96.72	0.00e+00	2603.00
IUUC-Pan-092381	Papio anubis	96.43	0.00e+00	2600.00
IUUC-Psi-093819	Pelodiscus sinensis	85.92	0.00e+00	2387.00
IUUC-Pma-094480	Petromyzon marinus	62.42	0.00e+00	1253.00
IUUC-Pfo-096561	Poecilia formosa	79.54	0.00e+00	1720.00
IUUC-Pab-097643	Pongo abelii	96.57	0.00e+00	2596.00
IUUC-Pca-100944	Procavia capensis	77.58	0.00e+00	1025.00
IUUC-Pva-102732	Pteropus vampyrus	87.59	0.00e+00	2306.00
IUUC-Rno-105113	Rattus norvegicus	94.75	0.00e+00	2590.00
IUUC-Sha-107608	Sarcophilus harrisii	83.89	2.00e-176	611.00
IUUC-Sar-113201	Sorex araneus	84.46	0.00e+00	1705.00
IUUC-Ssc-115469	Sus scrofa	95.37	0.00e+00	666.00
IUUC-Tgu-117322	Taeniopygia guttata	83.48	0.00e+00	2329.00
IUUC-Tru-118705	Takifugu rubripes	67.34	0.00e+00	674.00
IUUC-Tsy-119433	Tarsius syrichta	82.12	0.00e+00	1449.00
IUUC-Tni-120631	Tetraodon nigroviridis	76.96	0.00e+00	1775.00
IUUC-Tbe-127553	Tupaia belangeri	86.06	0.00e+00	692.00
IUUC-Ttr-128260	Tursiops truncatus	95.99	0.00e+00	2646.00
IUUC-Vpa-130479	Vicugna pacos	91.47	0.00e+00	2434.00
IUUC-Xtr-132686	Xenopus tropicalis	82.40	0.00e+00	2212.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence